600 mg cbd oil dosage for humans

CBD Oil Strength: How to Choose the Right One for You

You’re ready to buy CBD oil, but there are a dozen different potencies available. 300 mg? 600 mg? 4000 mg!? Which one should you choose? Buying CBD oil shouldn’t be so confusing. With this guide, we’ll show you exactly what makes these potencies different, and give you the information you need to become an expert. We go over:

  • What the most common potencies/strengths are
  • Differentiate between low, medium, and high strength oils
  • How to determine the actual strength of your CBD oil
  • And how you can apply this to choosing the best potency for what you need it for.

We then get into the more advanced techniques of calculating the optimal CBD concentration for your weight and size.

The Problem With Buying CBD

When browsing different brands, you’ll come across a lot of different strengths (potencies). You’ll find ranges from 300 mg to 4000mg per bottle. With so many CBD options to choose from it can make you feel like you have no idea what you’re even looking at. The labels are confusing and oftentimes, don’t make any sense at all.

The good news is that you’re not alone. The web is full of people asking similar questions. What’s the best potency for MS, fibromyalgia, pain, anxiety… the list goes on.

There are so many factors involved with CBD potency it’s no wonder people are so confused. The condition you’re treating, the concentration of CBD, whether or not other cannabinoids and terpenes are also present, and how severe your symptoms are will all play a role in choosing how effective it’s going to be.

Regardless of your final choice, keep in mind that CBD is not an FDA-approved drug in the United States and as such, this article should not be taken as a clinical claim or a medical recommendation. If you feel uncertain about picking the right strength of CBD oil and measuring the optimal dosage, consult your physician before the purchase. Let’s get into it.

Common Strengths/Potencies of CBD Oil

First of all, let’s clear something up. CBD potency specifically refers to how strong it is. If a CBD extract is rated at 300mg, it’s going to be about half as strong (potent) as the same amount of a CBD extract rated at 600mg CBD.

But wait, there’s more. These potencies also rely on the actual size of the bottle! The total CBD listed in mg refers to the dose contained IN THE ENTIRE BOTTLE. If you have a smaller bottle, the potency will increase.

So 300 mg in a 15 mL bottle will be twice as potent as a 300 mg oil in a 30 mL bottle. Confused? We’ll clear this up in more detail later. Keep reading, you’ll be an expert by the time we get to the end.

Why Are There different CBD Potencies?

As we said, there are many different potencies, but most of the time, you’ll come across two or three main options to choose from.

Needless to say, if you need CBD for regular supplementation or use it to deal with mild conditions, you won’t need CBD oil in high amounts.

A stronger oil might even be overkill.

As of right now, the majority of CBD companies sell oil tinctures in three different potencies:

Each of these potencies can come in a 15, 30, 50, or 60mL bottle. These are by far the most common, but there are also more potent 2000 mg and 4000 mg CBD options available too.

Getting Started With CBD Oils

It’s recommended that new users start with a low potency CBD oil. Of course, everybody’s chemistry is different, and what will work for one person might very well fail to deliver the desired effects for another not work for another.

The main thing to remember is to start slow and observe your body’s reaction to CBD. This way, you’ll be able to see how much of the oil it actually takes to provide the relief you’re looking for. For example, you can start with a 1-3 mg dose, and increase it to a 3, 4, or 5 mg dose later if these aren’t working.

If you’re not sure what we mean with these doses, keep reading, we’ll get to that later.

How To Calculate The Strength Of CBD Oil

The most important thing to remember when you buy CBD oil is to keep in mind that the bottle size matters.

What does this mean? Well, let’s say we have a 600 mg CBD oil in a 15 mL bottle, and another 600 mg CBD oil in a 30 mL bottle, which one is stronger?

The trick is to remember that the total CBD is distributed equally into the entire contents of the bottle, so the larger bottle will be roughly half as potent as the smaller bottle.

Here’s how it works.

There’s a simple calculation you can make to determine the strength of CBD oil.

It goes like this:

[AMOUNT OF CBD IN MG] ÷ [BOTTLE SIZE IN ML] = STRENGTH IN MG/ML

  • Anything below 5 mg/mL (10%) is considered low strength.
  • Anything between 15 and 30 mg/mL (15-30%) is medium strength.
  • Anything between 30 and 60 (30-60%) is high strength.
  • Anything else (60+%) is considered ultra-high-strength or classified as a concentrate.

Wondering how much CBD is in a serving of 300 mg (30 mL bottle)?

Let’s use this as an example. If you have a bottle with 30 mL of oil and advertises 300 mg of CBD, we can simply fill out the formula:[300 mg CBD] ÷ [30 mL Oil] = 10 mg/mL. This is like saying that 10% of the oil is pure CBD. It’s a 10% extract.

This means that every mL of oil you take will deliver exactly 10 mg worth of CBD. Here’s a simple equation:1 serving = 15 drops of oil = a 7.5 mg dose of CBDFor lots of people, though, even as little as 5-7 drops (about 3.5mg of Cannabidiol) can bring relief.

Let’s get into the concepts behind small (300mg), medium (600 mg), and large (1000mg) dose CBD products.

Low Potency CBD Oil (10% or Less CBD)

Most of the low potency CBD oil comes as 300mg in a 30mL bottle, which is a 10% potency. For a large number of people, this 300mg oil will be strong enough to support the endocannabinoid system and offer benefits to conditions like:

  • Mild-to-moderate anxiety [1]
  • Body aches and pains [2]
  • Mild headaches
  • Periodic insomnia
  • Mild to moderate stress

If you’re in the group of users who are particularly sensitive to CBD and other cannabinoids, you won’t require a strong oil to get the expected effects. The low-potency options are a good solution for people thinking of adding CBD oil to their supplementation plan. A single daily dose of CBD can boost immune health, improve homeostasis (balance), and shield you from a range of nervous and endocrine conditions.

Medium Potency CBD Oil (15-30% CBD)

This potency is a good option for those who are looking to elevate their intake of CBD further. Many people taking this dose found little or no benefit from the smaller dose. Typically, people use this dose for symptoms like:

  • Mild to moderate pain
  • Chronic inflammation
  • Digestive issues
  • Mild to moderate anxiety
  • Insomnia
  • Mild to moderate headaches

If you notice that you need to take large and/or multiple doses of the 300 mg (30 mL) version to get results, it’s time to upgrade to something stronger.

High Potency CBD Oil (30-60% CBD)

High-potency CBD oil isn’t for everyone. This is a therapeutic grade potency, used mainly for treating specific medical conditions. Conditions that often require high potency CBD oil Include:

  • Moderate to severe pain
  • Chronic inflammation
  • Cancers
  • Moderate to severe anxiety
  • Severe insomnia
  • Frequent migraine headaches
  • Multiple sclerosis
  • Epilepsy

If you notice that you need to take large and/or multiple doses of the medium-strength CBD oils, it’s time to upgrade.

Ultra-High Potency CBD Oil (>60%)

2000 mg of CBD in 30mL of oil will yield 66% CBD per mL. These products are thick and syrupy due to the high CBD concentration. They’re also referred to as concentrates because in order to make their manufacturers need to be extracted, and concentrated by removing other elements first. If you’re a first-time user, don’t start with high potency CBD oil.

Its effects are powerful and can have pharmaceutical-like effects in some people. They’re mostly used for serious medical conditions rather than for mild or even moderate levels of discomfort. It’s uncommon to find this potency in a bottle like the other options because it’s simply too thick. Instead, you can expect to find ultra-high potency products in a syringe application.

Unless your symptoms are serious, you likely won’t have to think about using this ultra-high-potency oil. Stick to the low or medium potency range instead.

Choosing Your CBD Dosage: Pro Tips

It’s time we elaborated on a few simple tricks to help you calculate your dosage and choose the right strength of your CBD oil. Let’s explore this in more detail.

1. Calculating Your Dosage Based On Your Body Mass

It’s the evergreen rule for measuring the doses of most substances. People with less body mass need less CBD to experience its benefits, while larger people will require higher amounts of Cannabidiol to produce the same results. Makes sense right?

A good rule of thumb is to take between 1 and 6 mg of CBD for every 10 pounds of body weight. So this would convert to:

  • 1mg/10lbs for low severity
  • 3mg/10lbs for medium severity
  • 6mg/10lbs for high severity

The calculation would be:

[BODYWEIGHT IN POUNDS] ÷ 10 x [DOSE ACCORDING TO SEVERITY] = DOSE IN MG

The low end is for fewer symptoms, the higher range is for more severe symptoms. Here’s a chart to help illustrate this:

Weight

a dose of 15 mg – 25 mg would be best for an individual who weighs 150 lbs, while a 200lb user will require somewhere between 20 mg and 33 mg to get started. The table below will help you estimate the dose and potency of your CBD oil: As mentioned, these are only general figures, and more likely than not, you will have to go through some trial-and-error before you reach the sweet spot.

2. Start Low And Work Your Way Up Gradually

Let’s say you have a friend who weighs no more than 150 lbs and takes 50mg of CBD twice daily, which gets him/her satisfying results. Then, he looks at you and says: “hey, we’re approximately the same weight, take the same amount of CBD for yourself – it will work.”Well, not necessarily.

Like we mentioned, we all have different biochemistry. We also all have different patterns of medication use, supplements, and other substances, each of with could interact differently with your CBD [3]. Even if you know the approximate dosage based on your body mass, you’ll need to experiment to see how your body reacts to different concentrations of Cannabidiol. From here we can adjust the dose accordingly until you know exactly how it’s working.

3. Consult Your Doctor

As much as we love to guide people on different aspects of CBD, we’re not in a position to give you medical advice. The best way to know whether you need a low, medium, or high potency CBD oil is to make an appointment with an experienced physician who knows CBD and can provide you with a professional CBD dosage guideline for your case.

How To Dose CBD? (Product Guideline)

You don’t have to be an industry expert to notice that CBD oil is not the only way to consume Cannabidiol. With that being said, you’re probably wondering how to measure your CBD dosage if you’re taking capsules or vaping flowers/concentrates/e-liquids.Here’s what you need to know about dosing CBD with the most common products:

Measuring CBD Tincture Dosage

CBD tinctures are by far the most popular way of consuming CBD. It’s also pretty simple; all you have to do is fill the dropper, place a few drops beneath the tongue, then hold it there for up to 90 seconds, and swallow.

But the question is: how much CBD is actually in a dropper?

Typically, a dropper has enough space to hold 1 ml of liquid. For most droppers, this will be about 40 individual drops. If you know the volume of your CBD tincture, you can use an easy formula to figure out how much CBD is in the dropper:

[TOTAL CBD CONTENT/BOTTLE] ÷ [BOTTLE’S VOLUME (IN MILILITERS)] = MGS OF CBD IN A DROPPER

The first step is to do our calculation from above to determine how much CBD there is in mg/mL.

Here’s a reminder of the formula in case you forgot.

[AMOUNT OF CBD IN MG] ÷ [BOTTLE SIZE IN ML] = STRENGTH IN MG/ML

For example, let’s say you’ve just bought a 30ml CBD tincture that has 300 mg of CBD. [300 mg] ÷ [30 mL] = 10 mg/mL

If a dropper holds 1mL of liquid, you can see that you’re getting 10mg of CBD with every full dropper (around 40 drops).

So, if you need to take 5 mg of CBD, and a single dropper of that 300 mg tincture holds 10 mg, simply fill the dropper halfway; simple, right? (Since we know a mL is about 40 drops, we can also just count out 20 drops).

Here’s another example: Let’s say you have 600 mg CBD oil, in a 15 mL bottle. Let’s first find out the amount of mg/mL:[600 mg] ÷ [15 mL] = 40 mg/mL.

Great! Now let’s say we wanted a dose of 80 mg. We need to take 2 dropperfuls to get that dose since one full dropper will have 40 mg of CBD. Done! Although this is not a surefire method, it is still better than shooting blinds.

Measuring CBD Vape Dosage

CBD can be vaped in two ways: either with a CBD e-liquid or by using a CBD cartridge system. Both methods are pretty straightforward and enjoyable.

Just like with a tincture, using an e-liquid to vape CBD boils down to estimating how much CBD a dropper can hold. Once you figure this out, you know how much CBD you are loading into your device.

Most people vape their daily CBD dose throughout the day, so if you suddenly run out of CBD in your cartridge, it’s a sign that you should puff the vapor in slower intervals. A single tank can contain approximately 33.33 mg of CBD if you are using a 1000 mg bottle.

Thus, the tank should last you for the entire day, leaving some CBD for the next session until you have to refill your device. When vaping CBD, regular monitoring is of the essence. This way, you will be able to control your CBD intake more accurately.

Measuring CBD Capsules Dosage

Now, if you’re wondering if there is a 100% accurate method to take CBD, the answer is a loud YES; these are CBD capsules. Because encapsulated CBD contains a fixed dose of the compound, they allow you to dose it precisely.

Let’s say your CBD dosage is 50 mg. In order to meet these numbers, simply buy a bottle of 25 mg capsules and take one piece twice daily; you will be good to go. Besides, what could be easier than swallowing a flavorless CBD capsule with water?

A Final Hit On CBD Strength And Potency

With the abundance of CBD-infused products and different strengths/potencies available on the market, choosing the right option for your situation can become challenging at the best of times. There’s a lot of information about dosing CBD out there, but without breaking this down into its smaller parts, you’re going to remain confused and frustrated forever.

We hope our guide on CBD potency will help you make the right decision when buying and measuring your CBD dosage. By practicing the calculations listed in this guide you can quickly become a wiz at dosing different strengths of CBD for yourself. If you have any questions regarding the dosage and available potencies, feel free to leave a comment below.

References:

  1. Bergamaschi M. M. et. al. Cannabidiol Reduces the Anxiety Induced by Simulated Public Speaking in Treatment-Naive Social Phobia Patients. Neuropsychopharmacology (2011); 36(6): 1219-1226. Published Online 2011 Feb 9.
  2. Reiman A., Welty M., and Perry Solomon. Cannabis as a Substitute for Opioid-Based Pain Medication: Patient Self-Report. Cannabis and Cannabinoid Research, Vol. 2, No. 1. Published Online in 1 Jun 2017.
  3. Rong C, Carmona NE, Lee YL, Ragguett RM, Pan Z, Rosenblat JD, Subramaniapillai M, Shekotikhina M, Almatham F, Alageel A, Mansur R, Ho RC, McIntyre RS. Drug-drug interactions as a result of co-administering Δ(9)-THC and CBD with other psychotropic agents. Expert Opin Drug Saf. 2018 Jan;17(1):51-54.
Nina Julia

Nina created CFAH.org following the birth of her second child. She was a science and math teacher for 6 years prior to becoming a parent — teaching in schools in White Plains, New York and later in Paterson, New Jersey.

Leave a comment Cancel reply

Your email address will not be published. Required fields are marked *

Save my name, email, and website in this browser for the next time I comment.

What Dosage of CBD Should You Take?

Kendra Cherry, MS, is an author and educational consultant focused on helping students learn about psychology.

Verywell Mind articles are reviewed by board-certified physicians and mental healthcare professionals. Medical Reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research. Content is reviewed before publication and upon substantial updates. Learn more.

John C. Umhau, MD, MPH, CPE is board-certified in addiction medicine and preventative medicine. He is the medical director at Alcohol Recovery Medicine. For over 20 years Dr. Umhau was a senior clinical investigator at the National Institute on Alcohol Abuse and Alcoholism of the National Institutes of Health (NIH).

Verywell / Madelyn Goodnight

CBD is available in a number of different formulations including creams, tablets, oils, and gummies. These can vary in terms of their ingredients as well as dosages, and there is not a great deal of research available on what dose might be beneficial or safe to treat certain conditions.

Cannabidiol (CBD) is the second most abundant cannabinoid found in marijuana. Unlike tetrahydrocannabinol (THC), CBD does not have psychoactive effects. Interest in the use of CBD for health purposes has grown tremendously in the last few years.

CBD is believed to have a range of positive physical and mental health effects. Because of this, it has become increasingly popular as a way to alleviate everything from anxiety to sleep disorders.

In order to determine if CBD is right for you, it is important to consider its potential benefits, side effects, and available research on safe dosages.

Possible Benefits

CBD is just one of hundreds of different compounds found in the cannabis plant. While cannabis has been used in holistic medicine for many years, only recently have researchers begun to explore some of the medicinal purposes for CBD and other cannabinoids.

While further research is still needed, there is some evidence that CBD may have some beneficial mental health effects. These include:

  • Alleviating depression: Some research also indicates that CBD may be useful as a treatment for depression. Studies suggest that the cannabinoid might have an influence on how the brain responds to serotonin, a neurotransmitter that plays a key role in mood. People with depression sometimes have a low level of serotonin, so CBD may help the brain use available serotonin more effectively.
  • Improving sleep: While the reasons are not entirely understood and require further research, CBD also appears to have potential as a treatment for sleep problems. For example, one study found that people who took CBD also reported improvements in the quality of their sleep.
  • Reducing anxiety: Anxiety is one of the most common types of mental health conditions, affecting almost 20% of American adults each year. Research suggests that CBD may help alleviate acute symptoms of a number of anxiety-related conditions including generalized anxiety disorder, obsessive-compulsive disorder, and social anxiety disorder.

In addition to the mental health benefits, CBD may also have therapeutic benefits for a range of other conditions. The World Health Organization suggests that CBD may have beneficial effects in the treatment of:

  • Alzheimer’s disease
  • Arthritis
  • Cardiovascular disease
  • Diabetes
  • Infection
  • Inflammation
  • Multiple sclerosis
  • Nausea
  • Pain
  • Psychosis

It is important to remember that these benefits have not yet been conclusively proven. More research is needed to determine the role that CBD might play in the treatment of different disorders and health conditions.

Research

There have been a number of studies that suggest that CBD may have a number of different physical and mental health uses. However, more research is still needed to better understand the substance’s potential applications and possible long-term side effects.

A 2019 comprehensive review published in The Lancet Psychiatry looked at previously published studies. The review ultimately concluded that there was little evidence to support the use of CBD for mental health purposes and suggested that more research is needed in order to substantiate its use to treat symptoms of conditions such as anxiety, depression, and insomnia.

It is important to remember that this doesn’t mean that CBD isn’t effective. Many of the studies that were included in the review were small, had few participants, and were not randomized controlled trials.

This suggests that more research involving more participants and well-designed studies is needed in order to better understand if, how, and why CBD works.

While its effectiveness is still up for debate, one 2017 review found that it was a relatively safe option.   While it is important to remember that there is still a great deal we don’t yet know about CBD and its effects, it is something that you might opt to try to see if you experience any benefits.

How Much Should You Take?

The dosages used in research studies vary and there is no consensus on how much should be used for specific conditions. If you do decide to try CBD, it is also important to note that there is no universally agreed upon dose. Research also suggests that people may respond differently to various dosages, so the amount that is right for your needs might vary.

CBD Dosages

Some dosages that have been used in research studies for different conditions include:

  • Anxiety: 300 to 600 mg
  • Bowel disease: 10 mg per day
  • Cancer-related pain: 50 to 600 mg per day
  • Parkinson’s disease: 75 to 300 mg per day
  • Poor sleep: 25 mg per day
  • Psychosis: 600 mg per day

One 2020 review of studies found that participants showed improvements in anxiety levels after single doses of CBD ranging from 300 to 600 mg.   Such results indicate that the CBD may hold promise as a treatment to alleviate symptoms of acute anxiety.

It is important to remember that you should always talk to your doctor before using CBD if you have symptoms of a serious mental or physical health condition. CBD could potentially worsen symptoms or interact with other medications you are taking.

Looking at the dosage information for the CBD product that has been FDA approved can also be helpful. For Epidiolex, an FDA-approved cannabis-derived medication used to treat seizures in people with certain types of epilepsy, the starting dosage is 5 milligrams per kilogram of body weight. This dose can later be increased to 5 mg per kilogram of body weight twice a day.

Other CBD products are not FDA regulated and do not have officially recommended dosages. This can make it difficult to determine how much you might need, but there are some things you can consider that might help.

  • Assess your sensitivity to CBD: Your individual ability to tolerate CBD can also play a role in determining how much you need. If you are very sensitive to the effects of CBD, you should take a small dose. Some people may find that they are not as affected by the substance, so they may need to take a larger dose to notice any beneficial effects.
  • Consider individual factors: When you are trying to decide how much CBD to take, there are a number of factors you should consider. These include the formulation and concentration of the capsule, oil drops, or gummies you are taking, the symptoms you are treating, and your age, sex, weight, and overall health. Generally, people with heavier bodies need to take a little more to achieve the same effects. Men may need a larger dose, while older people may need less.
  • Consider the symptoms you’re treating: The symptoms you are trying to alleviate can also play a role in the CBD dosage you need to take to see results. In one study, participants who took 25mg of CBD each day had improved sleep quality, although the results were not consistent.   However, you might find that you need a lower or higher dose if you are treating another type of condition.
  • Try a dosage calculator: Researchers note that while the variety of dosing strategies and formulations make it difficult to determine efficacy, there are a number of online “dose-calculators” available online (such as mydosage.com) that are designed to help people choose the correct dose.   The accuracy of such calculators is difficult to assess, but it may be a good place to start.

Before you try CBD, discuss your plan with your doctor. They may be able to recommend a dose and help you better understand any potential risks, complications, side effects, or interactions you might experience.

Start With a Low Dose

Unless your doctor recommends a specific dose, start by taking 10 to 20 mg a day. Take this for a week to ensure that it is well-tolerated and that you don’t experience any unwanted effects or an allergic reaction.

If this dose does not have the desired effect, try increasing in increments of 5mg each week until the desired amount is reached.

In studies, amounts vary from as low as 20 milligrams per day to up to 1,500 milligrams (mg) per day. The World Health Organization reports that dosages in clinical research studies typically range between 100 and 800 milligrams per day.  

Is It Possible to Take Too Much?

So what is the maximum amount of CBD you should take? Researchers have found that 600 mg per day appears to be safe, but one study suggested that doses of up to 1,500 mg a day are safe and tolerated well.

However, it’s important to remember that research is still in its infancy and experts do not yet fully understand the potential long-term impacts of CBD usage. For that reason, you should always discuss your CBD use with your doctor.

Starting at a lower dose and working your way up to the amount you need may be the best ways to avoid taking too much.

How to Take CBD

The amount of CBD found in a product may depend on different factors, including the formulation and method of administration. CBD products are available in a number of different forms including oils, capsules, tablets, nasal sprays, and gummies.

One of the most popular ways to take CBD is as an oil. Such products are made by combining CBD with some type of carrier oil, such as coconut oil. Some more recently developed products include dietary supplements, foods, beverages, lotions, salves, and cosmetics.

The type of CBD product you choose may depend on what you are trying to treat. If you are looking for general mood improvements, a dietary supplement might be a good option.

If you are targeting specific symptoms of a condition, taking an oil, capsule, or gummy might be a better way to obtain a higher, more concentrated dose.

Topical applications may produce localized effects, but they are unlike to have any mental health benefits.

What Kind Should You Take?

It’s also important to remember that many products don’t contain just CBD on its own. There are three types of CBD available:

  • Isolate contains CBD and only CBD.
  • Broad-spectrum contains CBD and other cannabinoids, but not THC.
  • Full-spectrum contains CBD, THC, and other cannabinoids.

It may be helpful to take a broad-spectrum product since research suggests that CBD’s effects may be most beneficial when taken in conjunction with other cannabinoids, a phenomenon known as the entourage effect. CBD may also help mitigate some of the effects of THC.

Side Effects

While CBD is generally well-tolerated, this does not mean that you won’t experience any side effects.

Some of the most common side effects that people experience when taking CBD include:

  • Appetite changes
  • Diarrhea
  • Nausea
  • Dizziness
  • Stomach upset
  • Weight changes

Some recent research has generated concerns over the safety and potential long term effects of CBD. One study involved giving mice an equivalent of the maximum dose of the CBD medication Epidiolex, which is used to treat certain forms of epilepsy. The results indicated an increased risk for liver damage as well as concerns over its interaction with other medications.  

Safety

It is also important to remember that CBD products are not regulated by the U.S. Food and Drug Administration (FDA). Some manufacturers make unproven claims about the uses and efficacy of their products. There is also concern about the quality and safety of the products themselves.

One report by the Centers for Disease Control and Prevention (CDC) indicated that a number of people experienced negative unwanted side effects due to CBD products that contained synthetic CBD, although the products were not labeled as containing such ingredients.

Mislabeling appears to be a fairly common problem with CBD products. In one study, 70% of the CBD products that were sold online contained significantly more of the psychoactive ingredient THC than the label indicated.

Federal law prohibits the sale of products that contain more than 0.3% THC. States laws also vary, so you should always check with your state before buying CBD products online.

A Word From Verywell

If you do decide to take CBD to alleviate an acute or chronic condition, remember that the amount that you take will depend on a variety of factors. Finding the right dosage often takes some experimentation and adjustments. Starting with a low dose and then gradually increasing the amount you take until you achieve the desired effects is the best approach.