Best CBD Oil For Hormone Balance

Hormonal imbalances can happen when levels fluctuate from what’s normal for you. These essential compounds affect every cell in your body, meaning that even a minor hormonal imbalance can cause a ripple of undesirable effects. CBD is an active ingredient found in hemp and cannabis plants that could help with hormone imbalances. Endocrine disorders include thyroid disease, metabolic syndrome, diabetes, & more. Check out the best CBD oils for hormone balance. There are many factors that can lead to hormonal imbalance and it is important for people to look for a solution. Much more research is needed on CBD oil. Learn about some of the causes of hormonal imbalance and some of the potential remedies out there.

CBD oil and hormones: can cannabidiol restore hormonal imbalance?

We look at how CBD oil could help with hormone imbalances.

Crying spells, trouble sleeping, emotions all over the place, and to top it all off, you can’t fasten your favourite jeans? You could be experiencing the highs and lows of a hormone imbalance.

Hormonal imbalances can happen when levels fluctuate from what’s normal for you. These essential compounds affect every cell in your body, meaning that even a minor hormonal imbalance can cause a ripple of undesirable effects.

CBD is an active ingredient found in hemp and cannabis plants that could help with hormone imbalances. CBD products could restore harmony and balance to your hormones and ease the symptoms that are making you miserable.

Can CBD oil help with hormone imbalances, and if so, how does it work? We speak to cannabinoid specialist and scientific advisor to Dr Julie Moltke about the efficacy of CBD for hormone balancing.

But first, let’s have a little background on hormones:

Understanding hormones

Hormones are chemical messengers. The endocrine glands produce these molecules in microscopic amounts.

The major glands of the endocrine system are:

  • The hypothalamus, pituitary gland and pineal body in the brain
  • The adrenal glands above the kidneys
  • The ovaries or testicles in the groin
  • The thyroid and parathyroids at the front of the neck
  • The pancreas in the abdomen

Hormones enter the bloodstream and travel to specific receptor sites in the organs and tissues where they cause changes to take place.

Hormones are essential for every bodily process, including:

  • Growth
  • Metabolism
  • Reproduction and sexual function
  • Body temperature
  • Emotions

They may be small, but they’re mighty. A slight excess or deficiency of a particular hormone can lead to health issues.

What is a hormone imbalance?

Hormones fluctuate and shift naturally throughout the day, during menstrual cycles, pregnancy, puberty, and menopause. These changes are predictable and mean your body is functioning normally.

Other hormone imbalances can happen if one of the endocrine glands produces too little, too much, or even stops producing hormones entirely.

Certain health conditions can trigger hormone imbalances, including:

  • Tumours of the endocrine glands
  • Diabetes
  • Under or overactive thyroid disorders
  • Cushing’s syndrome
  • Addison’s disease

Other lifestyle or environmental factors can also influence your hormone balance, such as being overweight, stressed, taking steroids, and even consuming high-levels of soy products.

Hormone imbalance signs and symptoms

Both men and women can experience hormone imbalances. The symptoms you experience can vary greatly and depend on the glands and hormones affected. Symptoms associated with hormonal imbalances include:

✔️ Changes in blood pressure or heart rate

✔️ Weight loss or gain

✔️ Excessive sweating

✔️ Difficulty sleeping and fatigue

✔️ Blurred vision and headaches

There are medical studies and anecdotal evidence that indicate CBD could help alleviate the symptoms of a hormone imbalance. CBD has a range of proven health benefits, and research into its full spectrum of effects is ongoing.

CBD and the endocannabinoid system

The endocannabinoid system (ECS) is complex. Doctors still don’t fully understand how this cell-signalling system works but know it has three components: enzymes, endocannabinoids, and two types of receptors, CB1 and CB2.

Its primary function is to control how your body releases the neurotransmitters that affect nerve impulses. The ECS could also be involved in regulating:

  • Fertility and pregnancy
  • Sleep
  • Appetite
  • Mood
  • Memory
  • Sensations

CBD, or cannabidiol, is one of the main organic compounds found in the Cannabis sativa plant. The medicinal use of CBD oil is growing in popularity because it confers health benefits without a ‘high’. Taking CBD oil boosts your endocannabinoids so that the ECS can work more effectively.

How does CBD oil influence your hormones?

Research confirms a link between the endocannabinoid system and endocrine processes.

‘We know that the endocannabinoid system has a role in maintaining balance in the body. It makes sure our body is acting within a narrow range of operating conditions; so-called homeostasis.’ explains Dr Moltke.

‘The ECS is known to regulate stress, mood, memory, fertility, bone growth, pain, immune function, among other things. CBD interacts with the ECS and with many other receptors in the body.’

Dr Moltke goes on to explain, ‘We are still highly lacking human studies that show exactly how this manifests in our different hormonal systems.’

CBD can influence major hormones, including insulin, cortisol, and melatonin.

CBD oil and insulin levels

Your pancreas produces the essential hormone, insulin. An imbalance can cause not only diabetes, but heart disease, and obesity.

‘We have long known that marijuana consumption seems to be related to reduced blood sugar levels.’ says Dr Moltke. She goes on to outline that ‘clinical experience and studies are showing that when diabetic people use medicinal cannabis, they can reduce their diabetic medicine or insulin as cannabis lowers blood glucose.

Further research is required to fully understand the effect of CBD on insulin levels. ‘We do not, however, know how CBD alone affects blood sugar or insulin. It probably does not have a direct effect on these measures, but the anti-inflammatory properties can be extremely valuable for type 2 diabetics, as it is a condition associated with chronic inflammation in the whole body due to high blood sugar levels.’

CBD oil and cortisol

Stress is bad for our blood pressure, mental state, and overall health. Cortisol, along with adrenaline, is involved in managing your stress response.

Cortisol is essential for survival. It’s responsible for controlling our natural ‘flight or fight’ response. If you produce too much cortisol, you may suffer symptoms, including weight gain, mood swings, and increased anxiety.

‘One study clearly shows that CBD is able to lower cortisol levels, a hormone associated with chronic stress’ explains Dr Moltke.

CBD oil and melatonin

If you don’t get enough sleep, your health will suffer. Melatonin from your pineal gland is responsible for your circadian rhythm, in other words, when you sleep and wake, and for managing your energy levels. For most people, it’s highest at night and lowest in the morning.

The ECS is involved in your sleep pattern. One study reported that the ECS activated CB1 receptors which affect sleep stability, how quickly you fall asleep and increases the level of melatonin produced.

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CBD and hormone imbalances in women

CBD might be able to help with the symptoms of normal monthly hormone fluctuations and those that happen during puberty and menopause.

• Mood swings

Many women experience anxiety and depression as part of their menstrual cycle and during menopause. Oestrogen and progesterone affect levels of serotonin, the so-called happy chemical that influences mood.

Research shows that CBD activates serotonin receptors and that in animal models, it shows anti-anxiety and antidepressant effects.

• Bloating

During menstruation, the uterine contractions that occur throughout your cycle are more intense. This causes food transit through the digestive system to slow down, leading to constipation and bloating.

The drop in oestrogen and progesterone before your period can also cause water retention.

There are cannabinoid receptors in the digestive system, and research confirms that the ECS is involved in the physiological control of colonic motility. CBD could, therefore, help with bloating issues by increasing gut motility.

• Pain and cramps

Some women find the pain associated with menstruation debilitating, others merely uncomfortable. Studies have shown that CBD works to relieve pain and relax cramping muscles.

As progesterone declines, prostaglandins increase, peaking during menstruation. These chemicals cause inflammation, heightened sensitivity to pain, blood vessel constriction, and uterine contractions. Although necessary for a regular menstrual cycle, high levels of prostaglandins can lead to more painful or heavier periods.

An enzyme (COX-2) is responsible for prostaglandin production. CBD inhibits COX-2 and can lower the level of COX-2 that you produce, thereby reducing inflammation, pain, and cramps.

CBD is widely recognised as having muscle and vascular relaxing effects, which also lead to a decrease in painful period cramps.

The way that CBD and the ECS work are complicated and further research is needed, but there is some evidence to suggest that CBD could help with the symptoms of a hormone imbalance.

⚠️ It’s always a good idea to check with your doctor before starting supplementation with CBD. The FSA advises that people who are pregnant, breastfeeding or taking any medication not to consume CBD products. Unless under medical guidance, CBD intake should be limited to less than 70mg a day.

Last updated: 14-02-2020

Zia Sherrell Zia Sherrell is a digital health journalist and content creator with over a decade of experience covering diverse topics from public health to medical cannabis, nutrition, and biomedical science. Her mission is to empower and educate people by bringing health matters to life with engaging, evidence-based writing.When she’s not typing madly, Zia enjoys travelling and chasing after her dogs.

CBD for Endocrine Disorders: Can CBD Oil Balance Hormones?

CBD targets a regulatory system in the brain that controls the balance of hormones.

Learn how doctors are using CBD to help patients with endocrine disorders.

Article By

The endocrine system is responsible for controlling everything from energy metabolism to reproductive health.

If there are any issues with this system, it can produce a range of uncomfortable, and often serious side effects.

CBD oil may be able to help.

It offers a wide range of supportive effects to this system and may be exactly what you need to get your body back on track.

Here, we discuss how CBD and the endocannabinoid system play a pivotal role in the endocrine system, and how it’s used for treatment.

Let’s get into it.


Carlos G. Aguirre, M.D., Pediatric Neurologist

Updated on November 15, 2021

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What Are The Benefits of CBD For The Endocrine System?

CBD is just one of about 80 different cannabinoids found in the cannabis plant. There are dozens of confirmed health benefits of CBD — many of which are helpful in supporting the health of the endocrine system.

These compounds are considered cannabinoids because of their ability to interact with a system in our body known as the endocannabinoid system.

The endocannabinoid system plays an important role in the body by maintaining homeostasis. This is often referred to as the body’s balance. Interestingly, this is also what the endocrine system does.

CBD and other cannabinoids may restore balance to this system directly through the hypothalamus and pituitary but also on the endocrine organs themselves.

The benefits of CBD oil for endocrine function includes:

  • Supports insulin production
  • Promotes weight loss
  • Regulates metabolic function & blood sugar
  • Supports mitochondrial health
  • Regulates energy levels
  • Reduces cortisol secretion
  • Promotes digestive health

What Are Endocrine Disorders?

There’s a whole bunch of disorders that can result from a dysfunctional endocrine system. Some of them may seem unrelated to each other, but it’s important to note that the endocrine system is very widespread, and involves many different organs throughout the body, all working together.

Our endocrine system is very important for maintaining balance in the body. It regulates everything from energy metabolism to red blood cell production.

In healthy people, the endocrine system is in constant feedback with itself, turning on and off to keep our various body metrics at an even plane.

When the system falls out of balance, the system falls apart, and we suffer health problems, some of which are more severe than others.

  • Diabetes — poor insulin production or function leading to high blood sugar levels
  • Metabolic syndrome — involves dysfunctional sugar and fat metabolism
  • Fatty liver disease — a buildup of fatty acids in the liver
  • Osteoporosis — poor bone metabolism leading to low bone density
  • Hashimoto’s thyroiditis — an autoimmune disorder that attacks the thyroid gland
  • Cushing’s syndrome — an autoimmune disorder affecting the adrenal glands
  • Grave’s disease — an autoimmune disorder affecting the thyroid gland
  • Addison’s disease — involves poor adrenal gland function
  • Goiters — low iodine causing an enlargement of the thyroid gland
  • Hyperglycemia — high blood sugar levels
  • Hyperparathyroidism — excessive parathyroid function
  • Hypoglycemia — low blood sugar levels
  • Menopause — an age-related change in female hormone balance
  • Obesity — excess storage of sugars and fats
  • Polycystic ovarian syndrome (PCOS) — involves a combination of androgen and insulin dysfunction

What is The Endocrine System?

Before we start, we’ll get into a basic understanding of how the endocrine system works.

The endocrine system is made up of a team of various glands found throughout the body, working together to keep the body in balance (homeostasis).

These glands secrete hormones to communicate with the rest of the body.

You can think of the endocrine system as a company.

The CEO is the hypothalamus, found in the center of the brain. It looks at the organization as a whole and decides where to make changes in the plan to make sure the company—our body—stays on track.

Just like the CEO of a company, the hypothalamus doesn’t make any of these changes itself. Rather, it delegates the roles to different departments, made up of other executive organs such as the pancreas, adrenal glands, thyroid, and others.

Each of these glands serves as the head of a particular department—Some control energy metabolism, growth, immune function, body temperature, or bone structure.

When the hypothalamus instructs, they then turn to their own teams of various hormones and neurotransmitters. It’s these workers that actually carry through the changes initiated by the hypothalamus.

This system is in constant feedback with itself, constantly checking to see how these changes are implemented, and what their effect produces.

The Endocrine Glands 101

There are 9 main endocrine glands in the body. Each one is considered an executive, with a particular area of specialization, all of which respond directly to the hypothalamus (the CEO).

Here, we’ll go into detail for each one, highlight some of the common endocrine disorders that can result, and how CBD and other cannabinoids are used to improve the function of these organs/glands.

1. Pineal Gland

The pineal gland is responsible for controlling sleepiness.

It gathers information from other areas of the brain that measure the visible light spectrum. It’s designed to react to changes in daylight from blue-light to red-light.

Red light waves are associated with early morning and late afternoon when the sun rises and sets. The angle of the sun shining through the atmosphere reflects the blue light waves, allowing the more penetrating red light waves to make it through.

This helps us recognize when we should feel sleepy at night.

Blue light only makes it through the atmosphere when the sun is directly facing us. This is the light we see during the day, which the pineal gland determines to be the time when we should be wide awake.

When the pineal gland only senses red light, it releases the sleep hormone melatonin. If this is interrupted with blue light, melatonin secretion slows down, making it difficult for us to fall asleep.

The effects of blue and red light waves are well-documented. large electronics manufacturers such as Apple have started incorporating this into their design. Many computer screens now have a blue-light filter to prevent the blue light from activating the pineal gland and affecting sleep when working into the evenings.

Side-Effects of Pineal Dysfunction:

2. Hypothalamus

The hypothalamus is the CEO of the endocrine system.

It’s responsible for controlling the majority of the endocrine system’s function by delegating to the organs what to do.

Functions Regulated by the Hypothalamus:

If there’s a problem with the hypothalamus, it can cause problems with any of the other parts of the endocrine systems.

Dysfunctions of the hypothalamus can result in the following conditions:

3. Pituitary Gland

If the hypothalamus is the CEO, then the pituitary gland is the vice president.

It listens to messages sent from the hypothalamus and carries this message to other endocrine glands through the secretion of hormones.

Pituitary Hormones Include:
  • Thyroid-stimulating hormone (TSH)
  • Luteinizing hormone (LH)
  • Follicle-stimulating hormone (FSH)
  • Prolactin (PRL)
  • Growth Hormone (GH)
  • Melanocyte-stimulating hormone (MSH)
  • Adrenocorticotropic hormone (ACTH)

If there’s an issue with the pituitary, it can cause problems at the organ level.

Side-Effects of Dysfunctional Pituitary Gland:

4. Thyroid Gland

The thyroid gland is responsible for controlling our metabolism.

The pituitary receives information from the hypothalamus, which it then forwards to the thyroid gland.

Using hormones, it directs the thyroid to either speed up or slow down.

In this way, the thyroid essentially controls how we use energy throughout the body.

The thyroid can increase metabolism to burn through more energy, generate more internal body heat, or burn excess fat.

It can also slow down to conserve energy and help us cool down in hot weather by avoiding excess heat production as a byproduct of metabolism.

There are two main issues that can arise with dysfunctional thyroid glands; hypothyroidism and hyperthyroidism.

In hypothyroidism, we don’t metabolize enough, everything slows down, and we become fatigued and tired. It also becomes easier to gain excess weight than to burn it.

In hyperthyroidism, we’re metabolizing too quickly. We can develop anxiety, insomnia, diarrhea, and heart palpitations as a result. It becomes easier to lose weight than to gain it with this condition.

5. Parathyroid Glands

The parathyroids are small glands that sit behind the thyroid. They control our calcium balance in the body and therefore play a significant role in maintaining blood pH homeostasis, calcium, phosphorus, and bone metabolism.

Just like the thyroid, there are two main issues that can result from dysfunctional parathyroids; hypoparathyroidism and hyperparathyroidism.

Hypoparathyroidism shifts the balance of calcium and phosphorous and can lead to long-term problems with the cardiovascular system and the nervous system. It causes calcium levels to drop and phosphorous levels to rise above healthy levels.

Hyperparathyroidism is a serious condition. It causes calcium levels to rise, resulting in osteoporosis, joint pain, kidney stones, and low immune function.

6. Thymus Gland

The thymus is the college for the immune system. It’s where immune cells such as T-lymphocytes go to mature.

The immune and blood cells are first made in the bone marrow, before traveling to the thymus where they are conditioned as trained assassins for the immune system.

Problems with the thymus can affect our immune function and are one of the main causes of autoimmune conditions such as myasthenia gravis and rheumatoid arthritis.

In these diseases, the immune cells are taught to attack the body instead of invading pathogens, leading to targeted joint or tissue damage in the body by our own immune cells.

7. Adrenals

The adrenal glands are responsible for everything from blood pressure to heart rate. Hormones produced by these glands include cortisol or cortisone. These hormones control our stress levels through the fight-or-flight response.

The adrenals also control our energy levels throughout the day and help regulate sexual function.

Problems of the adrenal glands include:

8. Pancreas

The pancreas is responsible for controlling our blood glucose levels through the hormones insulin and glucagon.

Insulin is important for moving sugars from the blood into the cells where they are used to power the cells. Glucagon is used to break down stored sugars to ensure the body has enough energy to function.

These two hormones require careful measurement and balance by the hypothalamus, or they can result in serious problems. Too much sugar can damage organs, while not enough sugar leaves us feeling tired, confused, and dizzy.

The pancreas is also responsible for producing many of the enzymes we use to break down our food.

Dysfunctions of the pancreas can lead to problems such as:

9. Testes & Ovaries

Last, but not least, we have the gonads. These are the sex organs of the human body.

They release hormones that control everything from growth habits, immune function, sexual health, and mood.

Both of these organs respond to hormones released by the pituitary to control their function.

Dysfunctional testes/ovaries can lead to conditions such as:

Men (Testes)
Women (Ovaries)

Common Treatments for Endocrine Disorders

Endocrine disorder treatment usually involves either inhibiting or promoting hormone production. While this sounds straightforward and relatively harmless, many adverse effects come with these drugs.

Treatments vary depending on the specific issue, but medications tend to fall into the following categories.

  • Pituitary and hypothalamic hormonedrugs (bromocriptine, lanreotide, somatropin, pasireotide)
  • Somatostatins (octreotide, lanreotide, vapreotide)
  • Dopamine and dopamine agonists (bromocriptine, cabergoline, pergolide)
  • Somatropin and somatropin agonists (mecasermin, pegvisomant)
  • Vasopressin and vasopressin agonists (desmopressin, tolvaptan, conivaptan)
  • Thyroid and antithyroid agents (teriparatide, levothyroxine sodium, potassium perchlorate, metimazole, thiamazole)
  • Insulin and noninsulin glucose lowering drugs (metformin, lispro, aspart, nateglinide)

Using CBD for Endocrine Disorders

CBD works directly through the CEO, the hypothalamus.

It acts as a business strategist, helping the hypothalamus do its job better than ever.

This has a trickle-down effect on the rest of the endocrine system organs, offering broad, but powerful benefits towards maintaining homeostasis in the body.

CBD May Be Able to Support Endocrine Disorders Such as:

Because of its ability to improve the function of the hypothalamus, rather than push it in one direction or another, it’s useful for restoring homeostasis overall.

This helps to repair conditions that involve dysfunction in both directions:

1. Metabolic Excess:
  • Hyperthyroid (Excess thyroid activity)
  • Hyperparathyroid (Excess parathyroid activity)
  • Hyperadrenalism (Excess adrenal activity)
2. Metabolic Deficiency:
  • Hypothyroidism (Deficient thyroid activity)
  • Hypoparathyroidism (Deficient functioning parathyroid activity)
  • Hypoadrenalism (Deficient adrenal activity)

Therefore using CBD oil for endocrine disorders is simple. Once you’ve found the right dose, you just keep taking the oil as conditions gradually improve.

Of course, as with any other medical condition, it’s important that you’re taking other measures to treat the condition. There are some medications that interact with CBD; never combine them or stop taking any medication in substitution for CBD oil without first speaking with your doctor.

Many of these conditions are chronic in nature (long-term and self-sustaining). Therefore, it’s likely that it will take a few weeks to a few months before you start to see noticeable benefits from supplementing with CBD oil.

You’re essentially toning the hypothalamus when taking CBD oil. You won’t see immediate changes from the benefits of CBD oil for these conditions. In some cases, CBD will never fully eradicate the problem.

Patience is key.

You most likely didn’t get sick overnight, so you can’t expect to get better overnight either.

Finding the Right Dose of CBD Oil for Endocrine Disorders

Whenever trying CBD oil for the first time, it’s important to start small and increase the dose gradually.

Even though hemp-derived CBD oil is non-psychoactive, it affects everybody differently.

Some people need large doses, in the realm of 40mg per day, while others need very small doses, around 2 mg per day.

Finding the right dose takes trial and error.

You should start with a small dose and add 2 or 3 mg per day.

You’ll know you found the right dose when you start to feel symptoms disappear OR after you experience some side effects. When this happens, you’ve found your upper limit and should lower the dose to the last one that didn’t produce side effects.

Best Ways to Deal with Hormonal Imbalance

Whenever there is a conversation about women’s health, the term hormones is sure to come up. When men hear the phrase, women’s hormones , they likely think of PMS and periods. The question is; what do you think of when you see or hear that phrase? Hormones are one of many components that allow the body to function properly. They communicate when things are going well, and let you know when the proverbial you know what has hit the fan inside our bodies. While that last statement is true for both men and women, hormones can play an even more impactful role in how female bodies function.

Hormones are produced by our endocrine system which includes the pancreas, thyroid, ovaries and adrenals. There are a number of ways your endocrine system can come under attack, causing imbalances in your hormone levels or function. I’m a solutions oriented girl so when I hear, imbalance , I immediately think there’s an issue and it needs to be resolved.

“The Women in Balance Institute explains that hormonal fluctuations can occur naturally during puberty, menopause, and perimenopause, but they can also be caused by toxins or an unbalanced lifestyle. Common symptoms of hormonal imbalance include menstrual irregularity, weight gain, mood swings, vaginal atrophy, and hair loss.”

So, how do you know if your hormones are out of whack and whether you need something to help? First let’s talk about what to look for.

Fatigue, anxiety, sudden weight gain or difficulty losing weight, insomnia, skin or hair changes, PMS, and low sex drive are all things that point to a possible hormonal imbalance. All of these issues do not have to occur simultaneously, or at all. But, if you are experiencing one or more of these imbalances, we should be able to identify the culprit. Insomnia is an easily identified condition.

If you are having any of the above issues and you are beginning to suspect your hormones are betraying you, it is important that you contact your doctor and have a comprehensive evaluation of your hormone levels. While it is good to have solid answers as to why there’s a problem with our bodies, we have options that can help us fix these problems.

Studies have shown that CBD has successfully helped to regulate the secretion of cortisol, which is the stress activating hormone. If you can regulate and reduce the amount of stress hormone released in your body, you can reduce the negative impact of cortisol on your body. We also know that other components of hemp oil (which Sugar and Kush CBD products are derived from) contain compounds such as omega fatty acids which are also proven to regulate hormones.

It is important to realize that CBD oil and edibles are not cure all magic elixirs. CBD products should be used as a part of a healthy lifestyle that promotes health and wellness.

Sugar & Kush CBD Helpful Links

Find out how CBD with no THC can be safe for drug tests.

Using CBD oil for anxiety and the benefits of using CBD Oil for anxiety are popular topics of studies world-wide.

Using CBD oil for pain can be a safe and effective way to find relief of symptoms for women.

CBD edibles can be an effective CBD product for pain relief, especially with our popular recipes for CBD baked goods.

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