Best cbd oil for.l nueropathic pain

Best CBD Oil for Pain: Top 10 Brands & Buyer’s Guide

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For many people, daily aches and pains are just accepted as part of everyday life, but what if this doesn’t have to be your reality? While there are over-the-counter and prescription painkillers to help with sore joints or tired muscles, there are also all-natural options that are worth considering.

CBD, also known as cannabidiol, has become one of the most popular plant-based alternative treatment options for pain. But, starting a new supplement without knowing how it may impact you can be scary. For some, knowing that CBD is related to the cannabis plant can be pretty disconcerting.

While you may be apprehensive about using CBD for pain management, the fact is that there are hundreds of safe, effective CBD products on the market. Because there are so many products to do from, we’ve done all of the research for you so that you can focus on figuring out which high quality CBD product you want to try.

When selecting the best CBD oils for pain, here are some of the factors we considered

1. Look at what the experts and consumers have to say about a product. More often than not, you’ll get the best information about a product by looking at what CBD experts, researchers, and long-time consumers are saying. These are trusted, unbiased voices that can steer you in the right direction when choosing a CBD oil.

2. We analyzed more than 5,000 user reviews on brand websites along with social media, including Facebook, Instagram, and open forums like blogs and Reddit.

3. Reviewed our readers’ opinions, reading more than 8,000 email subscribers through a survey, which polled readers’ views on specific products.

4. Studied brand websites to confirm the veracity of important information. We looked at how transparent a brand is, along with farming practices, extraction methods, and other details.

5. Tested more than 15 products from some of the most recommended CBD oil brands. This allowed us to personally experience the efficacy, potency, safety, and value of these products.

Top 10 CBD Oils For Pain

When rating the top ten products, there are several factors that we considered to ensure that each product is effective, safe, and offered a worthwhile value.

Factors that Helped Choose the Best CBD Oil Brands

Hemp can be grown in almost any climate, which means that companies can technically source hemp from anywhere around the globe. But, a quality CBD oil will only be made with CBD sourced from plants that are grown in the U.S. or EU. These places have regulated farming practices, which means the plants are grown with high levels of quality control. These hemp plants are typically grown without pesticides and herbicides, and are GMO-free.

There are three different types of CBD extracts that can be used in an oil-based product. The first is CBD isolate, which contains pure CBD. The second type of broad spectrum CBD, which contains other compounds such as cannabinoids, terpenes, flavonoids, fatty acids, and other plant-based material. What broad spectrum CBD doesn’t contain is THC.

But, in the third type of extract, which is full spectrum CBD, there is a trace amount of THC. All legal CBD oil products must contain less than 0.3% by weight. So while THC is present, it won’t make you feel high or overly euphoric. It’s just enough to encourage the entourage effect, which enhances the effects that CBD has on the body.

The more potent the CBD is, the more efficient and effective it will be. Most CBD oils denote in milligrams how much CBD a dosage contains. What’s nice about CBD oil is that users can adjust the dosage as needed, just by simply taking more or less drops.

While a higher potency CBD will give you a bigger boost, low to mid potency oils offer more flexibility in adjusting dosage as needed. Low to mid potency oils are best for new users, as taking too much CBD can cause unintended side effects.

A product that’s available in many different sizes also offers another effective way to adjust the dosage as needed. You’ll find that many brands offer a variety of sizes, including 15mL, 30mL, and even 60mL options.

Flavor and aroma all play a part in the overall experience of taking CBD oil. The more enjoyable tasting a product is, the better experience you’re likely to have. It’s also much easier to take something consistently if you like the taste.

In the CBD oil world, you may have to dabble in some trial and error to figure out what you prefer. Strong flavors can cause headaches, but mildly flavored oils will still have a bitter, hempy flavor that many people simply don’t like.

The good news is that there are all sorts of flavors that brands use when making CBD oil more palatable. Whether you like fruity flavors, dessert flavors, or something in between, you’re sure to find one that you and your taste buds enjoy.

When looking at flavored CBD oils, pay close attention to how the product is flavored. Natural and organic flavorings are safer.

Ingredients are important, no matter if you’re buying a food supplement or a wellness product. The combination of ingredients used in a product influences many factors, including the quality of experience as well as the effects on the body. Ideally, you’ll want to only use CBD oils that are made with natural and organic ingredients, as they have better, safer effects on overall health. Avoid artificial chemicals as much as possible.

A brand can say and market anything they want about their product. The only way to confirm what CBD oil contains is through lab testing. Transparent brands will send their products off for testing by an independent, third party lab. These labs test for quality, safety, potency, and contents.

Being able to know exactly what a CBD oil contains invokes trust and peace of mind for consumers, especially those who are new to using CBD products.

A brand’s value is based on its customer satisfaction. The more happier customers a company has, the more reputable they are in the industry. While not everyone will be 100% satisfied with a product 100% of the time, you can often get a good idea of a company’s reputation by browning its customer reviews.

Look for products that have mostly 5-star reviews, as this means that customers were pleased with the performance, quality, and safety of the CBD oil.

There are still a lot of unknowns in regards to CBD. This is why it’s so important for companies to be open, honest, and transparent about their business practices. A brand that values transparency will welcome discussions and customer reviews.

Transparent CBD manufacturers will also provide information about farming practices, manufacturing, extraction and test results.

Customer service is the backbone of any successful, trustworthy company. Brands not only have to offer high quality products, they must also have a solid team of customer service experts who are available to answer questions and assist in any ways needed.

Shipping, Return & Refund Policies

The CBD industry is competitive, so it’s important to find a company that offers customer-focused shipping, return, and refund policies. Many brands offer rewards programs as well as discounts. This is great PR for the company and it also improves the customers’ overall experience and satisfaction.

Most people shopping for CBD oil are doing so online. This is why website experience is so important. Brands should have a website that is easy to navigate, informational, and usable on all devices and platforms.

Customers shouldn’t have to click through dozens of pages to find the information they need. A quality website should be well mapped out and offer a balance between text and imagery. The idea is to create an experience that is good enough to entice a customer to make a purchase now and again in the future.

1. Penguin CBD

Rated the #1 CBD brand by Rolling Stone, Penguin CBD sells CBD oil along with other CBD-infused products that are made with high-quality broad-spectrum CBD extract. The brand has been mentioned in other notable sources, including Merry Jane, Healthline, and Maxim.

Penguin CBD claims to be obsessed over creating high quality CBD that uses nothing but the highest quality ingredients. Their impressive lab results prove this to be absolutely true. Their dedication to providing trusted, safe, and effective products is also evident when reading customer reviews and other information on the company’s website.

All hemp plants are grown in Oregon using rich soil and safe, sensible regulations. They are also cultivated using organic practices and contain no pesticides.

So why the name Penguin CBD? Penguins waddle on and keep calm. They dive into life and live pretty simply. They find warmth among friends, work together to face challenges, and keep their cool, even under immense pressure. The owners of Penguin CBD believe that their products help people to embrace a simple, calm penguin lifestyle by restoring balance back to the mind and body.

Product & Brand Highlights

● Refined broad spectrum CBD

● Green Scientific Labs

● Infinite Chemicals Analysis

● Free 2-5 business day shipping

Return & Refund Policies

● Full refunds are available within 30 days of purchase if you are unsatisfied with the product for any reason.

● Bright and uplifting. Easy to use and navigate. Offers a ton of information, including a blog run by Penguin CBD.

2. FOCL’s CBD Drops

FOCL is a premium CBD brand based out of Los Angeles and Denver. The team at FOCL (short for Focus) is passionate about wellness and obsessed with producing plant-based products that actually work. Alongside their top-rated CBD Drops, FOCL also has premium CBD gummies and unique wellness formulas designed specifically for Focus, Sleep, Pain Relief and Immunity.

FOCL’s CBD Drops are ranked by Healthline as one of the best in the industry and get rave reviews from loyal customers for taste and quality. Beyond great taste, we were very impressed with the organic ingredients, cannabinoid profile, and extensive third party testing of FOCL’s CBD Drops. It’s obvious that FOCL doesn’t cut corners and goes above and beyond to produce the best CBD oil possible.

If pain relief is what you’re looking for, FOCL CBD Drops deliver. We recommend the 2000mg drops for best results and value. We also love their powerful Relief Cream . Check out their Relief Bundle for best value.

Product and Brand Highlights

Hemp Source: Grown in the USA using organic and sustainable practices

Extract Type: Broad spectrum CBD in 2000mg and 1000mg strengths

Flavors:
Ingredients

· True Broad Spectrum CBD (test results show a robust profile of minor cannabinoids)

· Organic MCT Oil

· Organic natural flavors

Lab Results

· Published on website

Shipping Policy: Free shipping for orders $65+ and for all subscriptions

Return & Refund Policy: Full refund available within 60 days of receiving order

Website Experience: Easy to navigate by intended usage with tabs for Focus, Relief, Sleep, Gummies, and Drops.

3. Everest

Everest is a rising star in the CBD arena and a brand we’d recommend keeping an eye on in the future. If their first forays into CBD are any indication, they’re going to be a big name in the market soon.

Everest’s full spectrum CBD oil is an easy recommendation for those looking for relief from their aches and pain. Their formula delivers a 5:1 ratio of CBD to other cannabinoids. That includes a considerable 2mg of THC with every 1mL dose.

Their extracts are derived from hemp grown within the United States. They also undergo a rigorous amount of lab testing to ensure purity and that customers receive the promised amounts of cannabinoids. The results for each new batch can be viewed on their product pages.So far Everest’s products include their signature CBD oil and CBD gummies, as well as Delta 8 oil, gummies, and vape cartridges. It’s a well-rounded lineup for any cannabis enthusiasts out there.

Product & Brand Highlights

American grown hemp

Full spectrum CBD

Organic MCT Oil (Medium Chain Triglycerides)

Full Spectrum Hemp Extract

Green Scientific Labs

Free 3-5 business day shipping

Return & Refund Policies

Full refunds are available within 30 days of purchase if you are unsatisfied with the product for any reason.

Clear, pleasingly designed, and simple to navigate. Easy to find the product pages, as well as the policy pages.

4. R+R Medicinals

R+R Medicinals is quickly becoming one of the most trusted and popular CBD brands by proving one thing – they make the CBD that works. Using supercritical CO2 extraction on their proprietary Cherry strain of USDA Certified Organic hemp, they yield an unparalleled profile of cannabinoids, terpenes, and other phytonutrients in their products that translate into guaranteed performance. Their 1000mg Fresh Mint Tincture is their best seller and of incredible value for a Full-Spectrum product at $46.99 – that’s under 5-cents per mg!

R+R boasts impressive levels of CBD, CBG, CBC, CBN, CBL, and more in their products so you can truly feel the entourage effect. They also publish third party certificates of analysis on their site for every batch they make. In addition to being USDA Organic Certified, they are also US Hemp Authority Certified, and they have hundreds of 5-star ratings on Google, so you can take comfort in knowing they do things with the highest standards of safety and quality in mind.

They offer an array of products ranging from cream and gummies to dog chews and soft gels – all made with their Organic hemp as the input, so you can pick exactly the product you prefer. If you’re new to CBD, R+R Medicinals is a great place to start to get high performance CBD at a price that won’t break the bank.

Product & Brand Highlights

● USDA Organic, Colorado Outdoor-Grown Hemp

● Gummies: Peach, Strawberry, Apple

● USDA Organic Hemp Extract

● Organic MCT Oil from Coconut oil (product dependent)

● Organic Natural Mint Flavoring

● Free shipping on all U.S. orders

Return & Refund Policies

● 30-Day Guarantee on all Products

● Easy to navigate, clean and professional feel. Veteran discounts, subscription discounts, and an in-house customer service team that uses a texting contact mode.

5. Leaf Remedys

Leaf Remedys CBD oils are sub zero extracted from the highest quality organically grown Colorado hemp. The advantage of this extraction method is that a high-quality hemp plant can become a full spectrum extract without any further extractions resulting in a more preserved and purer Full Spectrum oil retaining all the natural cannabinoids and terpenes. High quality full spectrum extract is a much more promising therapeutic choice than an oil extracted using other extraction methods and chemical processing which results in a full spectrum oil more known as a distillate Full Spectrum that is not as effective as a true Full Spectrum like leaf remedys full spectrum. They also offer an Broad Spectrum oil for those with THC sensitivity or are worried about the small THC content in Full Spectrum oil due to employment reasons. The THC is removed from their Broad Spectrum oils with an organic process which preserves a lot of the cannabinoids and terpenes. Leaf Remedys is a brand dedicated to the cause and proud to offer an all-American product at a very fair price. Their oils are offered at 500mg, 1000mg, and 2000mg strengths. They also offer a 1000mg CBD gel, and 50mg Full Spectrum CBD Gummies which is one of the highest on the market.

· High quality Full and broad-spectrum oils

· Free shipping Anywhere in the united states

6. BATCH CBD

BATCH is more than worthy of a top spot on our Best CBD oil for Pain list. They are one of the few vertically integrated brands in the industry, and therefore can offer highly effective products for a great price. They even boost their oils with natural anti-inflammatory terpenes for enhanced results.

All products are made in house using their signature full-spectrum CBD extract and mixed with the finest organic ingredients. Customers often review BATCH’s tinctures as some of the best CBD oils available as they are known for their attention to detail with a focus on functional products. The only goal at BATCH is to make a product that works.

Based out of Milwaukee, WI, BATCH was started by three young founders while roommates at the University of Wisconsin. With background in Chemical Engineering and Business, the trio quickly elevated BATCH to one of the most reputable CBD oil brands in the industry. They believe the secret to their success is taking pride in being “Midwest nice” and giving every customer the personal attention they deserve.

Product & Brand Highlights

● Full-Spectrum hemp extracts

Full-Spectrum Hemp Extract

Organic MCT Coconut Oil

Organic Natural Flavor Oils

Natural Terpene Blend

● Desert Valley Testing

● Free shipping on all domestic orders (3-4 business days)

Return & Refund Policies

● 30-day satisfaction guarantee. BATCH will fully refund your order if not satisfied.

● Simple and easy navigation with a beautiful aesthetic. Offers supplemental education and outlines every detail of their extraction process.

7. Colorado Botanicals

Colorado Botanicals is a CBD company with an unrivaled dedication to quality and high standards. As a result, Observer crowned the brand as the #1 CBD company to buy from in 2021. The company’s founder established the brand in 2017 after searching for CBD for a loved one with cancer and realizing how difficult it was to find a reputable product. He created Colorado Botanicals to improve scientific transparency in the industry.

The brand’s broad spectrum CBD products stand out from competitors in two distinct ways – preservation of terpenes and its proprietary extraction and purification process. When it comes to purification, most brands use high heat. This removes unwanted compounds from CBD, like waxes, chlorophyll, and fats, but it also burns off essential compounds like terpenes.

Terpenes are critical to CBD’s effectiveness. They have several health benefits, and when they’re combined with cannabinoids, those benefits (like the entourage effect) are much stronger. Colorado Botanicals uses a pharmaceutical chemical separation process, naturally retaining hemp-derived terpenes versus adding them in from other plants and diluting the CBD.

A lot of brands tout the effects of terpenes in their products, but Colorado Botanicals shows the proof. It conducts in-house lab testing with the same liquid chromatography equipment used by third-party labs and then sends every batch of its products to third-party labs for unbiased, independent testing. The brand posts that reporting on its website, showing the types of terpenes in its CBD and their quantities – an unprecedented level of transparency in the CBD industry.

Additionally, Colorado Botanicals uses organically grown hemp in its products and produces its full catalog in an ISO 9001:2015 facility that upholds the highest standards. And, the brand offers a variety of CBD oils for all needs, ranging in potency from 750mg to 3,000mg . In short, this is incredibly high-quality, responsibly made CBD for a great value.

Product & Brand Highlights

● Organically-grown Colorado Hemp

● Broad Spectrum CBD Extract

● MCT Oil (contains coconut)

● Broad-spectrum CBD extract

● Flavoring (if applicable)

● Free 3-5 day shipping over $50, $4-6 for orders under $50

● Priority and overnight options available

Returns & Refund Policy

● 60-day risk-free trial

● Prepaid shipping label provided to send products back (opened and unopened) for a full refund

Modern and user-friendly with access to a great deal of product information and third-party lab results. Intuitive, engaging, fast, and incredibly helpful in leading customers to the right product.

8. Verma Farms

Verma Farms is the gold standard of CBD. While this brand is also known for its overly delicious gummies, which are inspired by the Hawaiian islands, Verma Farms also sells award winning CBD oils. In fact, their CBD oil kit was ranked #1 by Forbes and Entrepreneur Media. With this, you can buy with confidence knowing that Verma Farms is a trusted and highlighted brand.

All Verma Farms CBD products are pure, powerful, and pesticide-free. Whether you’re looking for pain relief, better sleep, or overall rejuvenation, this company is sure to have just the product for you. The well-rounded CBD oils will boost your mind, body, and spirit, so that you can feel and be your best every day.

Verma Farms as a company is inspired by the island of Maui. According to the owners, this island felt pure and untapped, and because of that, Maui is now home to Verma Farms. The company strives to provide products that show just how pure and powerful nature really is.

The brand proudly uses organic, pesticide-free, and GMO-free cannabis plants. Verma Farms has an expansive line of CBD products, including tinctures, gummies, dried fruit, topicals, capsules, and even treats and oils for dogs.

Product & Brand Highlights

● Lemon Lime (Focus)

● CBD isolate (product dependent)

● Coconut oil (product dependent)

● Hemp oil (product dependent)

● Kosher-grade Vegetable Glycerin (product dependent)

● Free shipping on all U.S. orders

Return & Refund Policies

● Returns of unopened products are accepted within 30 days of purchase.

● Shipping costs are covered if return is due to company mistake.

● Uplifting yet soothing website. Easy to use. Use of graphics and animation creates an engaging experience.

9. Medterra

5:1 ratio of CBD to other beneficial cannabinoids

Contains CBD + THC, CBG, CBN, CBC, CBDV, and natural terpenes

Contains 2mg THC in each

U.S. Hemp Authority™ Certified & 3rd party lab tested

Available in 750mg, 1500mg & 3000mg strengths

Citrus and Chocolate Mint

30-day Money Back Guarantee

Each and every Medterra product begins with a simple seed grown in fertile American soil. Home grown, home harvested, and made to exceed the rigorous standards of the U.S. Hemp Authority™ and the Kentucky Department of Agricultural Industrial Hemp Pilot Program, Medterra’s True Full Spectrum CBD is made using a proprietary whole plant extraction process.

Their 5:1 ratio of CBD to other beneficial cannabinoids, flavonoids, and terpenes means that you’ll be receiving the full spectrum of benefits that the hemp plant provides.

Product & Brand Highlights

Hemp Source : American Grown

Extract Types: Full Spectrum Hemp Extract

Flavors: Citrus and Chocolate Mint

Organic Medium-Chain Triglyceride (MCT) Oil

Full Spectrum Hemp Extract Natural Flavors

Naturally occurring Cannabinoids: CBD, THC, CBG, CBN, CBC, CBDV, Natural Terpenes

Lab Results: Green Scientific Labs

U.S. shipping takes 2-3 business days

International shipping available

Free Shipping on subscription orders

Return & Refund Policies: 30-day money-back guarantee

10. Kiara Naturals

For those seeking a stronger solution designed specifically for Pain we highly recommend Kiara Naturals. A premium Swiss manufacturer known for its high potency and problem specific CBD remedies.

Kiara is a family-owned business that makes everything by hand, in small batches in Appenzellerland, Switzerland under strict GMP standards. Their products have been heavily adopted by Osteopaths, Chiropractors, Acupuncturists and Herbalists all over Europe due to their high-quality ingredients and certifications.

Their Full spectrum CBD oils ranges from 1000mg-3000mg and their Pain Tincture is formulated with full spectrum CBD and other strong plants from alternative medicine that work really well at addressing pain through multiple mechanisms.

Get 15% off using our exclusive code at checkout: discover15

Product & Brand Highlights

● Ultrasonic Full-Spectrum and pure hemp extracts

· Full-Spectrum Hemp Extract

· Organic MCT Coconut Oil

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● Free shipping on all US orders

Return & Refund Policies

● 60 day money back guarantee if it doesn’t work for you.

● Modern and really easy to use. Great educational articles and ingredients pictures and breakdowns.

Bonus: Sunday Scaries

Sunday Scaries CBD oil tincture is one of our top picks for pain management for numerous reasons. In addition to using a special broad spectrum blend of CBD oil, Sunday Scaries tincture also incorporates Vitamin D3, Vitamin B12 and coconut oil into its formulation.

Vitamin D3: According to the National Institute of Health , “recent interventional studies have shown promising effects of vitamin D supplementation on muscular pain”.

Vitamin B12: According to the National Library of Medicine , “B12 may be an additional tool to consider for pain treatment”

Coconut Oil: According to Healthline , “Human studies suggest that eating coconut oil may reduce markers of oxidative stress and inflammation.”

What’s more: Sunday Scaries has a 97% customer service rating, which is always handled in-house, by a member of their team. Plus Sunday Scaries offers an industry-best refund policy: 100% lifetime money back guarantee, so there’s no buying risk.

Still not convinced? Try Sunday Scaries cbd oil tincture , which Spy.com called the “Best Tasting CBD Oil” with Discover Magazine’s exclusive 20% off code: DSC20 .

Product & Brand Highlights

● USA grown hemp (outside Denver, CO)

Custom Formulated Broad Spectrum CBD

Broad Spectrum CBD Oil

Organic Coconut Oil

ACS Laboratory: Cannabis & Hemp Specialists

Free Shipping on Orders Over $59 & Subscriptions

Return & Refund Policies

100% Lifetime Money Back Guarantee

Bonus: WillowCBD

WillowCBD is a brand you should be aware of due to their attention to detail and high quality CBD products, including oils, gummies and creams. All of WillowCBD’s products are made using Colorado grown hemp and are totally pure and pesticide free.

By only using full-spectrum CBD their products can be used effectively for sleep, pain management, anxiety and rejuvenation. With a variety of CBD oil strengths and flavors available, WillowCBD is sure to have a variant that is right for you. Choose from 500mg, 1000mg or 2000mg strengths and natural, mint or citrus flavors. If you’re new to CBD we recommend trying out a few strengths and flavors to determine what works best for you.

Product & Brand Highlights

● Colorado grown hemp

● Full spectrum hemp oil

● 2-3 Business Day via USPS

Return & Refund Policies

● Returns of unopened products are accepted within 30 days of purchase.

Very easy to use and product pages contain a lot of information about the products, including ingredients, usage recommendations and customer reviews. WillowCBD also has an educational blog for those that are looking to learn more about hemp.

How Does CBD Help in Combating Different Kinds of Pain?

Chronic pain is a condition that impacts millions of people each year. In fact, according to a 2019 report released by the Centers for Disease Control and Prevention (CDC), around 20.4% of adults experienced chronic pain and 7.4 adults had chronic pain that limited life and/or work activities.

The report also found that chronic pain and high-impact chronic pain not only increased with age, but was highest among adults aged 65 and older.

With so many adults facing chronic pain, it’s no surprise that the use of over-the-counter pain medications, along with prescription pain medications, such as opioids, have increased over the last few years. In 2019, the CDC warned against the excessive prescribing of opioids in its Misapplication of the Guideline for Prescribing Opioids for Chronic Pain report.

Chronic pain can be caused by all sorts of underlying factors, including internal and external injury, infection, inflammation, and the degeneration of bones and muscles caused by daily wear and tear.

Because there are so many things that can cause pain, making it hard to pinpoint the true source, it’s only natural that people would turn to opioids for pain management. The problem is that these drugs are highly addictive and often lead to abuse and dependency.

Over the last few years, the U.S. has been plagued by an opioid epidemic. The fact is that opioids are misused, causing many to become addicted and dependent on the drugs.

Opioids are strong pain relievers. They work by making pain sensations, but they don’t solve the underlying cause of pain. This means that in order to keep pain at bay, patients must take these medications daily. Seizing use enables the pain to return.

This vicious cycle has created a major opioid crisis in the U.S. According to the Centers for Disease Control and Prevention , opioid overdoses kill millions of Americans each year. Here’s what the data from 1999 to 2017 shows:

● 1999-2017: More than 700,000 overdose deaths

● 2017: 68% of drug overdose deaths were linked to opioid abuse

● Opioid-related fatalities in 2017 were six time higher than those in 1999

● Each day around 130 Americans die from an opioid overdose

Back in the 90s, opioids were nothing more than a minor addiction problem that only seemed to pop up in certain regions. However, more than 20 years later, it has turned into a serious health crisis in America.

The good news is that CBD brings some hope to such a dark situation. CBD is not only safer and more effective than opioids, it carries no dependencies and actually treats the underlying cause of pain versus masking the symptoms. This ray of hope is sure to save countless lives.

The 2018 Farm Bill legalized all hemp-derivatives, making CBD and similar compounds legal at the federal level.

While many are still skeptical about the safety and efficacy of CBD oil, the use of this compound has only continued to grow. From critically ill patients to athletes, more and more people have turned to this natural alternative to safely manage their pain.

When talking about chronic pain, we aren’t just talking about sore feet from walking all day or a sore back from sleeping in a bad position. Chronic pain is debilitating and life-destroying. It can strip away one’s happiness, relationships, and hobbies.

In fact, chronic pain may be caused by or could be the symptom of a wide range of serious health conditions, including:

● Irritable bowel syndrome

● Headaches and migraines

● Neuropathic pain/nerve pain

● Lower back pain

● Osteoarthritis and rheumatoid arthritis

But whatever the cause or symptom, CBD may be able to effectively manage it. The best part is that CBD has no adverse or undesirable side effects. It contains no addictive properties, and it actually helps the body to minimize stress, inflammation, and other conditions that can influence pain.

CBD doesn’t work like opioids, which makes it a safer and more dependable option for those who live with chronic pain. Here’s how these two substances are vastly different.

● CBD is NOT addictive. The World Health Organization (WHO) released a full report that analyzed CBD and found that the compound doesn’t have any addictive properties. This means that it won’t lead to dependence. People can use it for months at a time without having to worry about getting hooked.

● CBD is NOT intoxicating . Unlike THC, the cannabinoid that causes a sense of being high and even hallucinations, CBD doesn’t have any psychotropic effects. This means you won’t feel overly euphoric or out of control after taking CBD oil.

● The body does NOT develop tolerance to CBD . This means that you can take the same dosage over and over again and still get the same results. In fact, some report that they need less CBD over time in order to maintain the same effects.

● Unlike THC, CBD does NOT directly act on the nerve receptors . When ingested, CBD works by indirectly hindering certain physiological functions. This is why the compound has little to no impact on the body’s chemical balance.

Even though some CBD oils use full spectrum CBD, which does contain trace amounts of THC, the amount is small and has very little effect on the body. Remember, all legal CBD oils must contain no more than 0.3% THC by weight. This small amount of THC is just enough for users to experience the entourage effect, which just heightens the effects and experience.

There are also products that are completely THC-free. If this is something you’re interested in, choose a CBD oil that uses CBD isolate or broad spectrum CBD. This way you don’t have to worry about any potential bad side effects.

The endocannabinoid system (EDC) plays a role in pain sensation. The system, which is spread throughout most of the body, receives and translates signals from cannabinoids. These signals can either tell the body to promote or hinder certain physiological functions, including hunger, sleep, immune response, and pain.

The ECS naturally produces endocannabinoids, which helps to manage all of these sensations and many others. When ingested, CBD plays an indirect role in the system and influences these sensations.

An endocannabinoid deficiency can result in physical issues, such as sleeplessness and pain. Because certain conditions can be caused by internal or external factors, endocannabinoids work within the body to overcome these symptoms to help us adapt. But when we lack certain endocannabinoids, pain and other issues can become intolerable. In this case, CBD can provide a much needed boost of cannabinoids, but without any psychoactive effects!

How CBD Interacts With The Body

No matter if you consume or inhale CBD, it works by traveling to the side of administration, and then makes its way into the bloodstream. Once absorbed, CBD is transported to the endocannabinoid system and interacts with many cannabinoid receptors, namely CB1 and CB2. CBD also interacts with non-cannabinoid receptors, including 5-HT1A, which is a serotonin receptor.

By attaching to these receptors, CBD influences the body’s reaction in inflammation, sleeplessness, pain, and other functions.

For topical application of CBD, it’s worth noting that CBD moves through the epidermal layer to reach the inner skin, muscle, and bone cells. Topical products don’t enter the bloodstream, which can benefit those who are taking certain medications that CBD may negatively interact with.

What the Science Says: Studies on CBD & Pain

While there’s still a lot to learn about CBD, there are several clinical trials and research studies that have found that the ECS and cannabinoids may play a crucial role in difficult to treat, chronic, and acute pain management.

Here are some of the studies that are worth highlighting that show the amazing role that CBD plays in curbing pain while also minimizing its intensity.

● A 2018 animal model clinical trial , which was published in the Frontiers in Pharmacology , was able to prove that CBD is a great inhibitor of neuropathic, inflammatory, and cancer pain. In this study, pain was artificially or chemically induced in mice to stimulate the required conditions.

● A 2016 review of several randomized controlled trials, published in the Schmerz , determined that cannabinoids are a safe and well-tolerated substance for treating chronic pain. The review found that cannabinoids are effective in treating pain caused by rheumatic diseases, including back pain, fibromyalgia, rheumatoid arthritis, osteoarthritis, and others.

● A 2018 generalized study , published in Molecules , found that there is ample proof that shows that CBD will become part of future developments in pharmacological, pharmaceutical and technological sciences. The hope is that this will lead to new and better therapeutic options and administration methods for using natural and synthetically-derived cannabinoids for treating pain.

● A 2019 randomized controlled trial , titled Analgesic Effects of Pharmaceutical-Grade Cannabis in Chronic Pain Patients With Fibromyalgia, found that pharmaceutical-grade CBD, also known as medical marijuana, may be highly effective in reducing pain in the human body.

There is still a lot to learn about CBD, but thus far, dozens of studies and trials have shown that CBD oils and other CBD products may be effective in treating pain and inflammation for short and long-term relief.

In fact, CBD has become so widely used that the Mayo Clinic Proceedings has released the Clinicians’ Guide to Cannabidiol and Hemp Oils .

How to Use CBD Oil for Pain

When extracted from the hemp plant, the end result is oil-based CBD. But, CBD oil can be infused and made available in many different forms, including tinctures, vape liquids, edible oils, capsules, powders, isolate crystals, and more. CBD oil can even be transformed and added to topical products and even delicious edibles, such as gummy candies and chocolate.

For this guide, we’ve mostly focused on CBD oils and tinctures, which are used sublingually. This administration method allows CBD to be absorbed by the glands under the tongue. So how can you best use CBD oil for pain management?

Here are some options to consider:

This method of taking CBD oil can involve using a tincture or spray that is applied under the tongue. The sublingual glands are able to absorb CBD directly into the bloodstream. After putting the oil under your tongue, you’ll need to hold it there for 6-90 seconds, and then you swallow it. Most people gulp the oil down while drinking some water. Any CBD content that remains in the swallowed liquid is absorbed by the digestive system.

Capsules and edibles are a convenient way to consume CBD oil. What’s nice about this option is that you don’t have to taste the CBD at all. Gummies and other sweet products can be infused with CBD oil for a flavorful way to manage your pain. Some people even add CBD to their daily smoothies and consume it that way.

All of these methods work by the body absorbing CBD into the bloodstream after it’s been metabolized by the digestive system. With oral administration, the bioavailability is extremely reduced, which decreases the effectiveness.

Some CBD oils that can be taken sublingually can also be vaped. While this form of CBD offers one of the highest bioavailabilities, it isn’t a safe option for everyone. Those with lung or other pulmonary issues should avoid using vaporizers.

There are all sorts of topical products, such as lotions, balms, salves, and patches that have been infused with CBD oils. These products are directly applied to the surface of the skin where there is pain or inflammation.

CBD Dosage for Pain

Now that you know the many ways you take CBD, you may be wondering what the best dosage is so that you can experience the relief you need. However, there is no one-size-fits-all dose. The effects of CBD are relative, so not everyone will have the same experience. The efficacy and efficiency of CBD used for managing pain is dependent on many factors.

Some of the variables that impact the efficiency of CBD include:

● Severity of pain

● Where the pain is felt

● Body’s ability to absorb cannabinoids

● Specific chemical balances within the EDC

When using CBD to treat severe conditions like chronic pain, it can be difficult to pinpoint the right dosage. But, with some trial and error, you will eventually find your sweet spot.

To make things even more complicated, the Food and Drug Administration (FDA) has not approved the use or sale of CBD as a foodor drug. This makes it much harder to make dosage suggestions. So at this point, dosages are open for interpretation.

However, it is worth noting that the FDA has approved a prescription drug called Epidiolex, which contains a naturally sourced, purified form of CBD. This medication is used to treat seizures caused by rare forms of epilepsy, including Lennox-Gastaut Syndrome and Dravet Syndrome. These conditions are typically found in young patients.

Even then, people of all age ranges, including elderly people, have experienced tons of success using CBD oil for pain management and pain relief. And while there is no set in stone therapeutic dose for CBD, most people have found relief by using doses that range from 2.85 to 50 mg/kg/day .

If you’re new to taking CBD, it’s best to practice restraint and patience. Start with a low dose and then slowly increase it until you find your sweet spot. For those who take medications or have underlying health conditions, it’s best to consult with a doctor who has experience using cannabis-derived substances as treatment.

Lastly, if you are looking to improve your health and energy you need to look at sleep as well. There are lots of way to improve your sleep . According to studies better sleep can lead to better concentration, more energy, faster metabolism and lower inflammation. All in all, good sleep will help you get the most out of the products above and set you up for long-term success on your health journey.

Looking for the best CBD you can find? Check out our awards for the best CBD Gummies , best CBD Oi l, Best CBD Oil For Dogs , and Best CBD Oil for cats .

Best CBD Oil for Nerve Pain Reviewed in 2022

Neuropathy involves not only pain but also other pesky symptoms such as anxiety, nausea, and vomiting, as shown in studies on painful peripheral neuropathies. If nerve pain plagues every day of your life, things like muscle spasms, joint inflammation, and stiffness can become unbearable.

People who used up their conventional treatment options, but to no avail, have recently started switching to natural resources, such as CBD oil, for their nerve pain. According to recent studies, CBD may ease neuropathy and help individuals manage their symptoms in a safe and effective way.

These findings are promising for people with neuropathy, even though it’s too early to make definite statements. In this article, we’ll present the data from the current research on this subject on top of our industry overview, where we give our recommendations on the best CBD oil for neuropathy.

Best CBD Oils for Neuropathy

The quality of CBD oil is paramount for your results with neuropathy. Unfortunately, no two CBD oils are made the same; in fact, there’s a large degree of difference in quality between brands. There are many great companies committed to quality, but there’s an equal number of fly-by-night brands preying on uneducated customers.

Having been in the business for 7 years, we’ve tried a plethora of CBD oils from dozens of different brands. This year was even more demanding in terms of the tested products considering the continuously rising popularity of CBD.

We’ve selected the top 5 CBD oils for neuropathy from over 40 companies that offer CBD oil in three different types: full-spectrum, broad-spectrum, and isolate. Our ranking is based on the quality criteria such as hemp sourcing, extraction methods, third-party testing, and customer service.

1. Royal CBD (Best CBD Oil for Neuropathy)

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Product Details

Potency 250 mg –2500 mg
Available Flavors Natural, Berry, Mint, Vanilla
CBD per serving 8.3 mg – 83.3 mg

Why Royal CBD is the Best CBD Oil for Neuropathy

Royal CBD was launched in 2018 in California by a group of cannabis aficionados with a vision to elevate the quality standards and customer service on the market after collecting their own experiences from the customer’s side. This premium brand offers full-spectrum CBD oil sourced from organic hemp and extracted with supercritical CO2. This method of extraction allows even high-potency oils to maintain the plant’s original chemical profile due to lower temperatures.

Royal CBD oil comes in four different strengths, including 250 mg, 500 mg, 1000 mg, and 2500 mg. For potencies between 250 mg and 1000 mg, you can choose between three flavored options, such as Mint, Berry, or Vanilla. The strongest version (2500 mg) is only available in the natural flavor, as adding flavorings would negatively impact the potency of CBD.

Speaking of high-potency oils, the 2500 mg bottle is my favorite product from Royal CBD. The hemp aftertaste is surprisingly mild because the oil has been infused into food-grade coconut-derived MCT oil. This adds another benefit because MCT oil also enhances the absorption of CBD.

If you experience nerve pain — whether regularly or from time to time (like me) — this potency will probably be your go-to choice. It has a deeply relaxing effect and can reduce inflammation for quite a long time after ingestion. I take it under the tongue, wishing the extract around my mouth to increase the surface area for absorption and minimize the amount of oil that passes through the gut.

  • Sourced from non-GMO, Colorado-grown hemp
  • Extracted with supercritical CO2
  • Contains full-spectrum CBD
  • Available in 4 strengths and 3 flavored options
  • Up to 2500 mg of CBD per bottle
  • Lab-tested for potency and purity
  • 30-day money-back guarantee
  • Slightly more expensive than the competition
  • No vape products available

2. Gold Bee (Best Organic)

Product Details

Potency 300 mg – 2400 mg
Available Flavors Natural, Honey-Kiwi
CBD per serving 8.3 mg – 33.3 mg

About Gold Bee

Our second-best CBD oil for neuropathy comes from Nevada, but Gold Bee is a true maverick among other brands due to the unique honey flavor of its full-spectrum CBD oil, which the company produces from locally grown, non-GMO hemp.

The quality of ingredients — just as the honey flavor — are award-winning in my opinion. This CBD oil has a very natural flavor, with an actual honey aftertaste, which makes this product particularly enjoyable to use. There’s no tart, earthy taste that you can feel with the majority of CBD oils.

When it comes to easing nerve pain, I noticed similar results to what I got with Royal CBD, but due to the lack of high-potency oils in its lineup, Gold Bee is the runner-up in this compilation.

  • Made from US-grown organic hemp
  • Contains the full spectrum of cannabinoids and terpenes
  • Up to 33 mg CBD/mL
  • Good potency range for new users
  • Lab-tested for CBD content and purity
  • No high-potency oils
  • Honey is the only flavored option

3. CBDPure (Top Transparency)

Product Details

Potency 100 – 1000 mg
Available Flavors None
CBD per serving 3.3 mg – 33.3 mg

About CBDPure

CBDPure is one of the most reputable US brands that specialize in making low-potency CBD oil, although the company has lately expanded their line up with a 1000 mg strength. This is a nice nod towards users who want to save more money on their CBD oil but their dosage doesn’t exceed 30 mg CBD daily.

CBD pure is also one of the most transparent companies on the market. The guys at CBDPure explain every step of how their oils are made, and surprisingly for low-potency extracts, these products provide decent results when it comes to pain relief. The only reason CBDPure scores third place on this list is because of the higher prices. Some users may find these oils less affordable than other premium brands in the long run.

Want to try if CBDPure products will work for you? The brand has a 90-day money-back policy. You can return the product for a full refund within 90 days if you’re unsatisfied with the results.

  • Sourced from Colorado-grown organic hemp
  • Extracted with CO2
  • 4 strengths to choose from
  • Lab-tested for potency and purity
  • 90-day return policy
  • No high-potency oils
  • Only two forms of CBD available
  • Priced higher than competitors

4. Hemp Bombs (Best CBD Isolate)

Product Details

Potency 125 – 4000 mg
Available Flavors Natural, Acai Berry, Orange Creamsicle, Peppermint, Watermelon
CBD per Serving 4 – 133 mg/mL

About Hemp Bombs

When it comes to the best isolate-based CBD oil for nerve pain, Hemp Bombs offers the widest selection of products. The company has covered the entire potency range for CBD oils, offering up to 4000 mg of total CBD.

This oil is a good alternative for people with neuropathy who, for some reason, want to abstain from taking any THC in their product while getting a decent dose of CBD per serving. Full-spectrum products contain up to 0.3% THC; while this isn’t enough to get the user high, CBD isolate is completely free of THC. This trait is particularly important for CBD users who are regularly tested for drugs at work.

Because CBD isolate is made from 99% pure CBD, it has no aroma and flavor, which makes it more versatile thankful-spectrum extracts.

On the other hand, you won’t get the synergy from other cannabinoids and terpenes with CBD isolate, so this company may not have the best products if you want to benefit from whole-plant extracts in your supplementation.

  • Made from organic hemp
  • Extracted with CO2
  • THC-free
  • Third-party tested for potency and purity
  • Up to 4000 mg of total CBD
  • 5 potency options to choose from
  • Flavored with synthetic ingredients
  • No synergy from other cannabinoids and terpenes
  • Most people don’t need so much CBD oil in their routine.

5. CBDistillery (Most Affordable)

Product Details

Potency 250 mg – 5000 mg
Available Flavors None
Potency 8.33 – 166 mg/mL

About CBDistillery

CBDistillery is one of the most reputable companies in the American market. The company has been selling premium CBD oils for over 5 years, becoming one of the largest brands in the USA. Started by a group of Colorado natives with a mission to produce high-quality CBD products affordable for everyone, CBDistillery offers two types of hemp extracts: full-spectrum and broad-spectrum (pure oil). Similar to the full-spectrum CBD, broad-spectrum extracts contain CBD along with other non-intoxicating cannabinoids, but without any traces of THC. The THC is removed from the product after initial extraction.

The CBDistillery CBD oil comes in a wide range of concentrations, from 250 mg to a massive 5000 mg of CBD per bottle. The strongest version provides 166 mg of CBD per milliliter, which usually lasts for months.

As for the results, I was satisfied when it came to pain and irritation. I also noticed that my stomach was calmer than before taking this oil. However, there’s a reason why I’ve placed CBDistillery at the very bottom of this compilation. Unlike competitor brands, this one doesn’t use organic hemp plants.

So, CBDistillery may not sell the best CBD oils out there, but considering the price, these are hands down the best CBD oils for neuropathy in their range.

  • Available as full-spectrum or broad-spectrum CBD
  • 5 strengths to choose from
  • Up to 166.6 mg of CBD per mL
  • Third-party tested for CBD content and purity
  • Very affordable
  • Sourced from non-organic hemp
  • No flavored oils

What Causes Neuropathic Pain?

Neurons within the body carry signals to the brain, including pain signals. While this sensation is anything but pleasant, it has one important purpose — to prevent injuries. Once you place your foot on a hot surface, the painful sensation will warn your brain against the danger.

That’s how the process is supposed to work in healthy people. But with patients suffering from neuropathic pain, that nervous signaling system falls out of whack. In simple words, your brain receives pain signals, and you feel the pain, but there’s no obvious cause of that feeling. And because of this, it’s difficult to find an immediate remedy.

What’s the matter with those wayward nerves? Most of the time, it’s the result of damage from a disease or physical injury, including:

  • Physical injuries: this is a very common cause of neuropathic pain, in which nerves get crushed, compressed, or severed.
  • Shingles: this condition is another cause of neuropathy, one that can transform into a painful disease called postherpetic neuralgia. This type of nerve pain can be particularly severe and immediate.
  • Cancer and other tumors: As they grow, tumors can constrict the surrounding nerves. Cancer cells can also grow out of the nerves on their own. Sometimes, chemotherapy or radiation can damage nerve cells too, resulting in neuropathic pain.
  • HIV: this autoimmune viral condition can lead to painful nerve damage. Nerve pain actually affects around one-third of HIV patients, and nerve within the hands and feed is one of the first symptoms that occur. Antiretroviral treatments can also lead to nerve damage that triggers pain.
  • Diabetes: if you have diabetes, you have a higher risk of suffering from nerve injury. At some point, consistently high levels of glucose accompanied by hypertension can damage the nerves.

These are just a few conditions that can cause nerve damage and lead to neuropathic pain. Others include vitamin deficiencies, hormone balances, constant exposure to stress, and more. In some rare cases, nerve pain can just occur without a reasonable explanation.

Experts on Neuropathic Pain and Its Prevalence

Nerve pain derives from the central or peripheral nervous system. These networks are made of the brain and spinal cord. The spinal cord runs down from the brain and through the center of the spine. The nerves stretching from the spinal cord and traveling throughout the limbs and head are the peripheral nervous system. All these structures work together, constantly exchanging signals about your body.

Dr. Suraj Muley, an esteemed neurologist and director of the neuromuscular division at Barrow Neurological Institute in Phoenix, there are several common points for patients with neuropathy. They usually include electric-like, shooting pain with an ice-cold sensation, sensitivity to touch, and feelings of numbness.

The nerves are important players for any kind of pain, as well as other types of sensations. According to Dr. Ryan Jacobs, a neuromuscular neurologist, pain messages are sent by the nerves. This often happens as a result of inflammation or injury that causes damage to body tissues such as skin, bones, or muscles. However, nerve pain refers to damage caused by an injury to the nerves on their own. He also added that in some cases, it can be damage to one significant nerve or a few minor ones that can contribute to a widespread nerve injury.

How Can You Determine the Cause of Neuropathic Pain?

Doctors first conduct an interview with their patients, asking about the symptoms, history of medical conditions, and running a short examination. A physician may check for such things as sensory loss using a pinprick on different parts of the body. If the patient doesn’t feel the impulse from the pinprick or other things, that could indicate neuropathy, as said by Dr. Eva Feldman, a professor of neurology at the University of Michigan.

Aside from the interview and initial examination, your doctor may recommend conducting additional testing, such as bloodwork, to gain a bigger picture of what’s the reason behind the neuropathic pain in your case. You may be asked to run a test called hemoglobin A1C to check your average blood sugar levels and exclude the possibility of diabetes. The doctor may also check if you have sufficient vitamin B12 levels; deficiencies in this vitamin can lead to nerve damage and numbness.

Treatment Options for Nerve Pain

Treating neuropathy is tricky due to its specific nature and the exact cause of the problem. When nerve pain is triggered by a condition such as HIV, diabetes, or cancer, tackling the underlying disease is undoubtedly the priority. However, this treatment won’t necessarily help with your neuropathic pain. Nerve pain may require a dedicated treatment, one that is different from the treatment for the disease that’s causing it.

Doctors typically use prescription painkillers depending on the type and severity of neuropathic pain. However, people can build a tolerance to the active ingredients in these medications, let alone the risk of addiction and several dangerous side effects, including lethal overdose.

Experts believe that 40 million Americans struggle with nerve pain. The impact of neuropathy on modern society is enormous, and for many of us, the potential side effects of pharmaceutical medications outweigh their benefits. It’s totally understandable that people have started to look for natural alternatives such as CBD oil.

Using CBD is an option for treating many types of pain. Studies have already highlighted a few mechanisms responsible for the versatility of CBD in mitigating pain signals. But can it help with neuropathic pain?

Why Some People Are Choosing CBD Oil for Neuropathy

Some forms of neuropathy can be easily treated and sometimes cured. If neuropathy is incurable, the treatment should aim at preventing further damage to the nerve and controlling symptoms.

CBD has been shown to have some therapeutic qualities that might assist patients with neuropathic pain and other symptoms linked to neuropathy such as suppression of the nerves like Carpal Tunnel Syndrome.

CBD vs Anxiety, Chronic Pain, and Vomiting

According to the American Chronic Pain Association, neuropathic pain is the type of chronic pain that occurs in the nerves in the peripheral nervous system due to injury or damage.

Anxiety, nausea, pain, and vomiting are telltale neuropathic symptoms, as noted by a study on painful peripheral neuropathies that was published in Current Neuropharmacology.

Research has shown that CBD may be useful in easing different types of chronic pain. Neuropathic pain falls into this category, but unlike other chronic pain conditions, neuropathy is particularly difficult to treat, according to the author of a paper on neuronal mechanisms of neuropathic pain.

On top of acting as a neuroprotectant, CBD also has some other therapeutic properties, including antiemetic and anxiolytic effects.

CBD vs Inflammation and Muscle Spasms

Neuropathy often results from chronic inflammation, such as in diabetes, which is the number one cause of neuropathic pain in the United States.

Neuropathy can also derive from autoimmune diseases, such as arthritis or lupus. Autoimmune diseases are linked to a higher risk of hypertension and cardiovascular problems.

CBD can inhibit inflammatory and neuropathic pain caused by autoimmune diseases. In a 2016 animal study published in the European Journal of Pain, topical application of CBD helped reduce pain and inflammation triggered by arthritis.

CBD’s remarkable anti-inflammatory effects were also demonstrated in vivo in a 2018 study published in the Journal of pharmacology and Experimental Therapeutics.

Moreover, CBD may help relieve muscle spasms, which is a common feature of nerve damage, often marked by uncontrolled and painful muscle twitches.

Sativex, a combined oral spray consisting of THC and CBD in a 1:1 ratio demonstrated high efficacy in helping with pain management in patients with neuropathic pain caused by nerve damage, peripheral neuropathic pain, rheumatoid arthritis, advanced pain, and spasticity from multiple sclerosis. The results were published in Neuropsychiatric Disease and Treatment.

Similar results were observed in a review of similar studies published in The Cochrane Database of Systematic Reviews in 2018.

The above review examined hundreds of studies on using cannabinoid-based medicines on neuropathic pain in adults. While not all of them turned out positive, there was significant evidence that cannabinoids could reduce nerve pain and other symptoms of this condition.

How Could CBD Oil Help With Neuropathy?

The endocannabinoid system (ECS) is essential for understanding how CBD works to relieve neuropathy. The health benefits of CBD and other cannabinoids result from their interaction with the body’s ECS, which is the major regulatory network in all mammals.

The ECS controls a wide range of biological processes, including immune response, sleep, mood, appetite, metabolism, memory, and pain sensation.

This system consists of two types of cannabinoid receptors — CB1 and CB2 — which are found in specific parts of the body.

CB1 receptors are mostly found in the brain and central nervous system, but there are some concentrations of these receptors in reproductive organs, lungs, liver, retina, and urinary tracts.

CB1 receptors are involved in-memory processing, pain sensation, mood, sleep, and motor regulation. Their activation is linked to neuroprotective responses, suggesting that the cannabinoids acting on CB1 receptors could help in the prevention and treatment of neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis.

When it comes to CB2 receptors, these are primarily located on the surface of the immune system cells and their associated structures. The activation of CB2 receptors is said to produce an anti-inflammatory response, minimizing damage to nerves and reducing pain.

The above qualities have been found to be potentially helpful for treating autoimmune conditions, such as Crohn’s disease, arthritis, inflammatory bowel syndrome, and chronic inflammatory demyelinating polyneuropathy (CIDP).

CBD doesn’t bind to any of the cannabinoid receptors; it does, however, act indirectly on them, causing similar actions as the substances that typically stimulate the receptor.

CBD also has more than 65 molecular targets. It can interact with other receptors in the body, such as the 5-HT1A serotonin receptor. Serotonin is a neurotransmitter that controls feelings of well-being and emotional stability. It can also modulate nausea, anxiety, and pain.

Pros & Cons of Using CBD Oil for Neuropathy

  • Can help with symptoms such as inflammation, anxiety, pain, nausea, vomiting, and muscle spasms
  • Non-addictive
  • Non-intoxicating
  • Has been recognized as safe by major health agencies including the WHO
  • Can be purchased without a prescription (locally and online)
  • Not approved as an official treatment by the FDA
  • Can interact with 70-80% of prescribed medications
  • Side effects include dry mouth, drowsiness, fatigue, and changes in appetite
  • Products sold online and in local stores are mostly unregulated

CBD vs Other Alternative Treatments for Nerve Pain

Alternative treatments for patients with neuropathy include the use of capsaicin, primrose oil, and amino acids.

Capsaicin is an analgesic compound found in hot peppers. A study examining the use of an 8% capsaicin dermal patch found that almost 71% of participants with cancer-related neuropathic pain experienced 90% relief.

Primrose oil may help ease neuropathic pain in people with diabetes, as stated by Mayo Clinic in an article regarding peripheral neuropathy diagnosis and treatment.

According to the same clinic, amino acids, such as acetyl-L-carnitine, may help people after chemotherapy as well as patients with diabetes.

Is there a way to combine the benefits of the above compounds with the analgesic effects of CBD?

Some CBD products come in the form of salves infused with capsaicin. In these CBD products, the capsaicin supports CBD’s natural pain-killing benefits to help with problematic spots on the body.

As for hemp oil, which is often added to CBD topicals, it’s an excellent source of essential fatty acids and amino acids. You can also look for topicals infused with primrose oil for enhanced anti-inflammatory effects.

How to Use CBD Oil for Neuropathy?

Figuring out how to use CBD oil for neuropathy can help you maximize your results. Sometimes, cream or gel maybe is your best option if you want to completely avoid ingesting the oil.

However, if you want to approach the problem from two different angles, we recommend that you use full-spectrum CBD drops as your primary means of CBD oil.

CBD oil should be applied under the tongue for approximately 60 seconds before swallowing. This method of administration ensures that the CBD absorbs into the bloodstream through sublingual capillaries, avoiding the first-pass effect in the liver.

Alternatively, you can take capsules or edibles if you have problems holding the oil in your tongue, but CBD taken orally takes more time to kick in. Capsules and edibles are a great option if you want to ease nerve pain in social settings, or when you need longer-lasting relief at the cost of delayed onset.

If you need something to help with localized pain, then a topical such as warming salve could provide some relief. Usually, people who take CBD for neuropathy combine the oil (or edibles) with topical products.

CBD Dosage for Neuropathic Pain

Everybody will react to CBD differently because we’re not made the same. You need to ask yourself a few questions.

How much pain am I in?

Is it chronic pain or does it just happen randomly throughout the day?

Do you want to take CBD oil to function better or take the nerve pain away entirely?

Other important considerations for CBD dosage include your weight, age, metabolism, overall health, and prior experience with CBD oil.

Customers usually take CBD oil as well as use a topical about 1–3 times a day. In order to find the right dose and strength for yourself, you’ll need to go through some trial and error, starting at the lower end of the recommended serving size, and slowly making your way up to the point where you experience a significant difference in your symptoms.

Safety and Side Effects of CBD Oil

CBD has a well-established safety profile. It can be taken under the tongue in doses of 300 mg – 1500 mg daily for up to several weeks. Dosage recommendations for prescribed cannabidiol (Epidiolex) range from 10 to 20 mg per kg regularly.

Some rumored side effects of CBD oil include dry mouth, dizziness, changes in appetite, and sedation resulting from a temporary drop in blood pressure. Signs of diarrhea have also been reported in some patients, but this is a very rare adverse reaction.

Final Thoughts on Using CBD Oil for Neuropathy

CBD has demonstrated the ability to reduce neuropathic pain in many studies. Not only that, but CBD can also help with other neuropathic symptoms, such as anxiety, nausea and vomiting, spasms, and inflammation.

As more studies are being conducted in this area, CBD may become the go-to treatment option for neuropathy in the future. However, CBD isn’t the only cannabinoid found in cannabis that can help alleviate neuropathy.

Full-spectrum CBD oil contains all phytonutrients naturally found in hemp, including terpenes, flavonoids, and trace cannabinoids. These compounds work together to amplify the health benefits of each cannabinoid, producing the “entourage effect.”

This is the best type of CBD for neuropathy. However, regardless of the product choice, make sure to check all marks on the quality checklist, including the source of hemp, extraction method, and third-party lab testing. If you don’t have the time to do your own research, you can use our recommendations from above.

Let us know in the comments if you use CBD oil for neuropathy — and how it works for you!

Nina Julia

Nina created CFAH.org following the birth of her second child. She was a science and math teacher for 6 years prior to becoming a parent — teaching in schools in White Plains, New York and later in Paterson, New Jersey.

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The Effectiveness of Topical Cannabidiol Oil in Symptomatic Relief of Peripheral Neuropathy of the Lower Extremities

Background: Peripheral neuropathy can significantly impact the quality of life for those who are affected, as therapies from the current treatment algorithm often fail to deliver adequate symptom relief. There has, however, been an increasing body of evidence for the use of cannabinoids in the treatment of chronic, noncancer pain. The efficacy of a topically delivered cannabidiol (CBD) oil in the management of neuropathic pain was examined in this four-week, randomized and placebocontrolled trial.

Methods: In total, 29 patients with symptomatic peripheral neuropathy were recruited and enrolled. 15 patients were randomized to the CBD group with the treatment product containing 250 mg CBD/3 fl. oz, and 14 patients were randomized to the placebo group. After four weeks, the placebo group was allowed to crossover into the treatment group. The Neuropathic Pain Scale (NPS) was administered biweekly to assess the mean change from baseline to the end of the treatment period.

Results: The study population included 62.1% males and 37.9% females with a mean age of 68 years. There was a statistically significant reduction in intense pain, sharp pain, cold and itchy sensations in the CBD group when compared to the placebo group. No adverse events were reported in this study.

Conclusion: Our findings demonstrate that the transdermal application of CBD oil can achieve significant improvement in pain and other disturbing sensations in patients with peripheral neuropathy. The treatment product was well tolerated and may provide a more effective alternative compared to other current therapies in the treatment of peripheral neuropathy.

Keywords: CBD; cannabis sativa; diabetic neuropathy; hemp; nerve pain; review..

Copyright© Bentham Science Publishers; For any queries, please email at [email protected]

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