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5 Severe Delta-8-THC Side Effects You Must Know

This year, delta-8 THC, a new marijuana relative, burst onto the national scene. It is an improved form of THC in the Marijuana family. It comes as a vape or an edible, and the state of trance is similar to a moderate form of traditional marijuana.

In terms of chemical structure—three carbon rings, a long tail, and several hangers-on—and psychological effects, delta-8 THC is similar to delta-9 THC, the critical active component in marijuana.

The way they originate is the main distinction. The raw marijuana plant contains delta-9. Delta-8, on the other hand, comes from hemp, a cannabis plant that has been cultivated to produce fiber, biofuel, and bioplastics without the psychotropic THC.

Delta-8-Tetrahydrocannabinol (or THC-8, Delta-8-THC) is popular with digital sellers because it avoids the laws that apply to its cousin, cannabinoid Delta-9-THC. It is possible to synthesize it from CBD oils, resulting in a high profit margin. Not to mention the intoxicating effects and how customers cannot get enough of it. Is THC-8, on the other hand, risk-free?

Even though Delta-8-THC originated in the early twentieth century, consumers, researchers, and regulators have only lately become aware of it. Surprisingly, there is hardly any awareness about its safety profile, particularly in vape pens and edibles. The research is on a small scale in most instances.

What is Delta-8-THC?

Delta-8 is a cannabis component that has grown in popularity due to its resemblance to delta-9 THC, the primary ingredient in cannabis that causes euphoria, happiness, sedation, symptom alleviation, and other effects. The majority of cannabis cultivars have high levels of THC. Chemical structures and terms are the only similarities between the two cannabinoids.

Delta-8 is an acronym for delta-8-tetrahydrocannabinol, which is also known as delta-8 THC. The effects of delta-8 THC are comparable to those of ordinary delta-9 THC, although they are significantly less powerful.

The legality of delta-8 is currently unclear. Hemp or cannabis may mix to make it. Hemp may now be cultivated and extracted legally across the United Areas, thanks to the 2018 agricultural bill, making delta-8 lawful in states where delta-9 THC is illegal—in some cases. Almost all Organic delta8 THC on the market today is made from hemp-derived marijuana, making it, at least in principle, part of a federally authorized supply chain.

People in places where THC is under ban want cannabis products, and delta-8 may be legal in their state, even though it is less potent than ordinary THC. To fulfill the gap between demand and supply, several hemp-based extractors are scaling up delta-8 production. It also is exported from the country to across the world.

5 Severe Side Effects of Delta 8 THC

Mouth dryness

One of the most prevalent adverse effects of smoking cannabis flower, whether Delta 8 or Delta 9, is cottonmouth or dry mouth. You will most likely feel parched as long as the Delta-8 molecule is present and active in your body. Many individuals drink a lot of water when taking Delta 8 to avoid this. However, a widespread misunderstanding is an occurrence of dehydration; this is not the case. It occurs as a result of the impact of enzymes on your salivary glands.

Dry eyes

It might not be a surprise to people who wear contact lenses. Consider how it feels to have left your eyes open for a minute. It includes continuously rubbing your eyes, trying to restore some moisture. However, like dry mouth, this lasts as long as Delta 8 is present in your system. This feeling of dry eyes will go away as the impact wears off.


Though Delta 8 alleviates paranoia and anxiety when consumed, consuming too much of it might make you feel jittery. Even though Delta 8 is said to have some of the psychotropic properties of Delta 9, ingesting large amounts of anything might create anxiety. When Delta 8 became legal, a uniform dose was also made available. However, if someone decides to go too far, they will almost certainly face negative consequences. Furthermore, because everybody is different, the effects of Delta 8 may vary from person to person. It is one of the reasons why Delta 8 must be under consumption in modest doses. It takes a bit for it to kick in, so the user should have an effective dose plan.

High-level trance state

Some individuals claim that Delta 8 gives them lightheadedness since it contains psychoactive chemicals, but they are not as potent as THC. It implies that anyone who has this experience is likely to become too concentrated on all of their ideas. On the other hand, they may find it hard to focus and start zoning out.

Inability to concentrate at work

It may be troublesome. However, it is dependent on when you consume Delta 8 . It is best to accomplish this in your spare time rather than while you are busy with work. Because Delta 8’s recognized effects are to relax you and give you a “high,” it is understandable that taking it during work hours might interfere with your productivity. Delta 8 may affect your cognitive and physical abilities, making it difficult to regain your attention.

Is It Legal?

Delta-8 THC is not technically prohibited, as we previously said. Here, we will look at some of the most complicated legal issues that surround this drug.

Several cannabis businesses openly market Delta-8 THC as a legitimate method to get high. That is technically correct, yet it is still a subject of contention for some. For one reason, it is not a prohibited drug. While Delta-9 THC comes under a blanket ban by federal and few state legislation, Delta-8 THC never comes under it. However, more to the point, many supporters will refer to the 2018 Farm Bill. This law made numerous industrial hemp products, including Delta 8, lawful on a nationwide basis.


Because Delta 8 is so new, there has not been enough study to determine the long-term effects it may have on you. The side effects we have mentioned are mainly short-term, and the customer will notice them within a few hours after ingesting Delta 8. Monitor your dose and eat according to the manufacturer’s recommendations. If you encounter any of the above-mentioned adverse effects, you should be patient and try not to be too concerned. They will only stay as long as you are high and then fade away.

The risk and benefits of Delta 8 products are balanced, and under controlled doses, it might well be the perfect alternative to other Marijuana products. Delta 8 can also cure the widespread opioid crisis in several states of the United States of America.


I have been smoking a Delta-8 pen before bed every night for about two weeks now and it has improved my sleep so much. However, last night I tried the gummies. They were 50mg each. I think if I had one I would have been fine. But I ate 3 before bed. I awoke in the middle of the night and the entire right side of my body was numb. I could barely walk to the bathroom. I started panicking that maybe I had a stroke or that a spider or something lethal had bitten me. This lasted for hours… I was scared if I fell asleep I might not wake up but I couldn’t even stand up or walk so there was no going to the ER. I have never had a physical feeling like that from any substance and I have been experimenting with drugs since I was a teen. I am relieved I’m absolutely fine today. Will likely continue to use delta because of its sleep aid however will only ever use in very small doses after my experience.

Nothing like cannabis. More like ACID or PCP. Horrible mental confusion (out of body feeling) extreme dry mouth, skin crawling nausea and alternating between hot flashes and chills. Blurred vision, double vision, extreme fatigue, awoke with crushing Vice grip headache with constipation (dried out) had to go leading to explosive diarrhea. This stuff is garbage and shouldn’t be legal. Just legalize cannabis already. Some people will eventually die on these Delta 8 concentrates. Don’t waste your money. Or risk a bad trip.

Never again I am at recovering math addict and I’m going to tell you the feeling I got off the Delta 8 was even worse from when I did math never again why I touch it

Absolutely horrible experience. Took 25 mg of delta 8 (hometown hero) for the first time 3 days ago and I still feel like shit. The feeling is not the same as weed. I monitored my heart rate with my watch while I was in the thick of it and my heart rate would oscillate from 55 all the way up to 124 repeatedly within minutes, up and down the entire time. The normal range is 64-79 bpm. I was also freezing the entire time and it was like 80° out. My tongue also went kind of numb. I tried it because I was wanting a mild energy boost, calming effect and help with focusing in the studio. Uh NO. I completely lost an entire day and most of the next. I became obsessed with like two songs and researching everything about them, but felt I couldn’t concentrate long enough on anything to be productive in the studio. It caused paranoia. It also made me feel nauseous. It stayed strong in my system from 4pm – 4am and I was afraid to fall asleep because I thought I would go into a coma. I woke up with immense vertigo. I hated the experience and I highly recommend anyone reading this to stick to natural weed. Three days later and I still have a hungover feeling, my heart rate doesn’t feel normal and I still have nausea and vertigo. Takongnlots of supplements and drinking lots of water hoping this lingering feeling will end. If you have ever experienced syncope, and know the feeling of when you know it’s coming, that’s sort of the state I’ve been for the last three days with constant cold flashes. I feel horrible to getting my partner to partake in it as well. He had an equally shitty experience.

I had a terrible reaction. It was my first time trying it and I thought I was buying a innocent cbd gummy for tooth pain because the guy sold it to my like candy, with no warning. I guess partly my fault for not reading the package better although if I had, I’d probably be dead because it said take 1-2 every 4hrs. Well after I took it I realized it was 50mg of Delta 8 and I honestly thought I was having a stroke. Not sure why my reaction was so bad but my whole body was numb for nearly 5hrs. I honestly thought I was going to die and had no health Insurance so didnt want to rush to emergency. I felt the need to do as much detoxing herbs as I could find to get the crap out of my system quickly or Im not sure I’d still be here. No more for me. I’ll just stick to my relaxation herbals like valarian etc. I’m in my late 50’s so maybe a younger, healthier person would have not had the same reaction as me but all I can say is “Good luck”.

The Potential Side Effects of CBD

Wendy Rose Gould is a lifestyle reporter with over a decade of experience covering health and wellness topics.

Verywell Mind articles are reviewed by board-certified physicians and mental healthcare professionals. Medical Reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research. Content is reviewed before publication and upon substantial updates. Learn more.

Steven Gans, MD is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital.

Verywell Mind content is rigorously reviewed by a team of qualified and experienced fact checkers. Fact checkers review articles for factual accuracy, relevance, and timeliness. We rely on the most current and reputable sources, which are cited in the text and listed at the bottom of each article. Content is fact checked after it has been edited and before publication. Learn more.

Karen Cilli is a fact-checker for Verywell Mind. She has an extensive background in research, with 33 years of experience as a reference librarian and educator.

Verywell / Alex Dos Diaz

Generally speaking, CBD is considered a safe substance when applied topically or taken orally. There are, however, some potential side effects to keep in mind when using this substance, the majority of which are mild.

Common Side Effects of CBD

The most comment side effects of CBD include drowsiness, gastrointestinal issues, dry mouth, reduced appetite, nausea, and interaction with other medications. Those are outlined in detail below.


Some common side effects when using CBD include drowsiness and sedation. This is also considered a benefit, but Dr. Jas Matharu-Daley, a physician and chief medical officer for a CBD brand, notes that the effects might be too strong if you’re also taking CBD with other sedating medications.

Gastrointestinal Issues

Some people may get diarrhea or liver problems [when using CBD]. This is dependent on the individual and their medical history, so monitoring is important,” says Dr. Matharu-Daley.

Dry Mouth

Also known as “cotton mouth,” CBD can potentially cause your mouth and eyes to feel very dry. Though this side effect is more likely to occur with THC, it can happen with CBD as well.

Can Interact With Other Medications

CBD might interfere with the other medications you take. Dr. Matharu-Daley says it’s important to talk to your doctor about whether CBD could affect your existing prescriptions.


In some cases, those who ingest CBD supplements might experience nausea, says Dr. Matharu-Daley. This depends on how sensitive the person is to CBD, as well as the amount they ingest.

Because CBD supplements come in so many different forms—such as oils, gummies, tinctures, and vapors—the amount that’s actually absorbed can vary drastically. This, combined with each person, will ultimately affect which (if any) CBD side effects you might experience.

What Is Cannabidiol (CBD)?

CBD—the abbreviation for cannabidiol, a substance that’s generally derived from the hemp plant—has skyrocketed in popularity over the last five years. In fact, according to research, “CBD” as a Google search term remained stable from 2004 to 2014 but has since ballooned by up to 605%.

CBD is one of the many chemical compounds that is found in the cannabis plant—referred to as cannabis sativa. There are two primary parts of the plant that humans use. One is THC, or Delta-9-Tetrahydrocannabinol, and the other is CBD. Though they’re from the same plant, THC and CBD are quite different from each other.

“CBD is not an intoxicating substance, whereas THC is a psychoactive that can get you high,” explains Dr. Jas Matharu-Daley, a physician and consultant for a brand that specializes in CBD production.

Are There Any Benefits Associated With Using CBD?

There are several reasons why someone might want to use CBD. The substance can be found in a multitude of products ranging from pain-relieving creams to edible tinctures to skincare. Research is still underway, but over the last few decades scientists have become more aware of how CBD might be beneficial when applied either topically or ingested.

“Since discovering the endocannabinoid system (ECS) in the body in the 1990s, CBD has been researched more extensively. The ECS is a central regulatory system restoring normal balance and homeostasis in a range of human physiologic systems throughout the body and brain and has cannabinoid receptors and chemicals in its function,” explains Dr. Matharu-Daley.

CBD benefits include the following:

  • CBD can have positive impact on the brain. In fact, Dr. Matharu-Daley says that the substance is legally prescribed in a specific medication for certain severe forms of epilepsy in children.
  • It has also been shown to have anti-inflammatory properties, which is why you often see CBD in topical products such as oils, creams, and lotions.
  • Some research points to CBD’s ability to relieve stress and anxiety.
  • It has been used as a nausea treatment in some countries.
  • CBD may potentially reduce pain symptoms.
  • It has antioxidant properties, which means it can help fight off free radical damages that leads to premature aging.
  • Regarding skincare, CBD may help reduce excessive oil production in those with very oily skin types.

Ultimately, the primary reasons why people use CBD is because it tends to have calming, relaxing, pain-reducing effects. It has been used to alleviate joint pain and nerve pain, reduce anxiety and stress, treat insomnia, improve migraines, and address nausea.

CBD Is Still an Unregulated Substance

It’s important to point out that CBD is not regulated by the FDA and therefore dosages might not be accurate. It’s also difficult to know what an appropriate dose is the first time you try a new product.

“If the CBD is from a reputable source and one that has been inspected by a third-party independent lab, the content of CBD is more reliable,” notes Dr. Matharu-Daley. “The CBD should be organically grown, free of pesticides and heavy metals, and not sourced in food which can affect absorption. Generally, CBD is safe and side effects are few at low doses.”

A Word From Verywell

CBD is technically an unregulated substance in the United States and therefore it ought to be used with caution. This is especially important for those taking additional medications and/or those with ongoing medical issues. That said, preliminary research on CBD and its benefits are promising in relation to helping with mild to moderate health concerns and it is generally considered a safe substance. Health professionals do not consider CBD a cure-all for serious medical issues, including cancer.

As with any sort of supplement, we recommend speaking to your medical doctor about whether using CBD makes sense for you. Your doctor can also recommend certain products that align with your needs and help ensure you get the correct dosage.