Charlotte’s web cbd oil for stress

Clinical Trial Shows Charlotte’s Web Hemp Extract’s Positive Effects on Stress, Sleep and Well Being

DENVER, Feb. 8, 2022 /PRNewswire/ – (TSX:CWEB) (OTCQX:CWBHF) Charlotte’s Web Holdings, Inc. (“Charlotte’s Web” or the “Company”), the market leader in cannabidiol (CBD) hemp extract wellness products, shares the positive results from a randomized, controlled, clinical trial study which evaluated the effectiveness of hemp-derived CBD extracts. Charlotte’s Web participated in the Radicle ACES (Advancing CBD Education and Science) study, conducted by Radicle Science, an independent health tech company validating health and wellness products. As part of a larger study, hundreds of participants from across the US used Charlotte’s Web Original Formula for four weeks and were assessed for key health outcomes across five domains including general well-being, quality of life, sleep quality, feelings of daily stress or discomfort. Researchers conducted the study using standardized scientific methods and validated indices for measuring each outcome and tracked their progress repeatedly throughout the study.

As a hemp company driven by sound science, we were encouraged by the Radicle Science study.

Charlotte’s Web President of CW Labs’ Tim Orr

Independent third-party research and reporting on the efficacy of hemp wellness products help build long term consumer trust and is an ongoing commitment of Charlotte’s Web.

“We’re applying modern science to prove or predict the effectiveness of CBD products used by tens of millions of Americans every day,” said Jeff Chen, MD/MBA, Co-founder and CEO of Radicle Science. “Our objective is to deliver accurate, transparent, and actionable insights to help create trust and transparency for the CBD industry.”

People in the study regularly taking Charlotte’s Web Original Formula on average realized a distinct and palpable improvement in their quality of life and well-being. A majority of people also experienced clinically meaningful improvements across the other health domains studied including sleep quality and feelings of daily stress or discomfort as compared to the baseline, before they started taking Charlotte’s Web. People on average showed significant improvements as compared to the control group who did not take any hemp extract.

This clinical trial helps confirm the benefits of Charlotte’s Web full spectrum hemp extract. 64% of participants with symptoms of stress experienced clinically meaningful improvements in their stress after taking Charlotte’s Web Original Formula, versus only 22% of the control group. 60% of participants struggling with sleep issues experienced clinically meaningful improvements in sleep quality, versus only 15% of the control group. And participants who took Charlotte’s Web experienced a significant 74% improvement in their well-being assessed using the World Health Organization (WHO)-5 Well Being Index. The study also showed that Charlotte’s Web worked quickly with notable improvements on average occurring within the first week, and generally reported effect onset within four hours after using the product. The study is therefore helpful in addressing a common question around hemp CBD: “How long will it take to work?”

Charlotte’s Web and other responsible participants in the CBD industry continue prudent research investment to contribute data on the safety and efficacy of hemp. This increases the standard of trust and transparency for consumers, healthcare providers, and regulators.

Jacques Tortoroli, Chief Executive Officer of Charlotte’s Web

Our Original Formula remains as effective today as when it was first developed by the founding Stanley Brothers years ago and took the world by storm. Consistency from year to year and bottle to bottle is a core driver of the trust that Charlotte’s Web has earned.

“The rigor, large scale and intentional heterogeneity of our studies deliver the first ever scalable path to validate the health effects of health and wellness products,” said Pelin Thorogood, Co-founder and Executive Chair of Radicle Science. “We are proud to partner with industry leaders such as Charlotte’s Web to inform evidence-based decision making for consumers, brands, healthcare providers and regulators alike, increasing trust and transparency for the CBD industry.”

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About Radicle Science

Radicle Science is a transformative health tech B-corp offering the first ever scalable path to validate and predict the health effects of health and wellness products, transforming them into democratized precision solutions for ailments or enhancement of human function. Radicle Science leverages a proprietary data analytics platform and a virtual, direct-to-consumer (D2C) clinical trial model to deliver objective health outcome data across diverse populations and conditions, at a fraction of the cost and time of traditional methods. Our Radicle Vision is a future where affordable, accessible, consumer health products are trusted by patients, recommended by healthcare providers, reimbursed by insurance, and used as widely as pharmaceutical drugs. To learn more, please visit and follow their LinkedIn page and Twitter page.

About Charlotte’s Web Original Formula™

In 2013, Colorado’s seven Stanley Brothers famously developed a unique CBD hemp extract to help a little girl (Charlotte Figi) in need, and changed global perceptions around the wellness benefits of hemp. Charlotte’s Web Original Formula™ full spectrum CBD hemp extract – first used by Charlotte Figi, the namesake of the Company – has been credited with supporting numerous wellness goals, improving lives, and launching a global CBD industry. The 2018 Farm Bill federally legalized hemp. Charlotte’s Web is the Worlds Most Trusted Hemp Extract™ and continues to lead the way for consumer access. Since its founding, Charlotte’s Web’s mission has been “To unleash the healing powers of botanicals with compassion and science, benefiting the planet and all who live upon it.”

About Charlotte’s Web Holdings, Inc.

Charlotte’s Web Holdings, Inc., a Certified B Corporation headquartered in Denver, is the market leader in innovative hemp extract wellness products under a family of brands which includes Charlotte’s Web™, CBD Medic™, CBD Clinic™, and Harmony Hemp™. Charlotte’s Web branded premium quality products start with proprietary hemp genetics that are 100-percent American farm grown and manufactured into hemp extracts containing naturally occurring phytocannabinoids including cannabidiol (“CBD”), CBC, CBG, terpenes, flavonoids, and other beneficial hemp compounds. The Company’s CW Labs R&D division, advances hemp science at two centers of excellence in Louisville, Colorado, and the Hauptmann Woodward Research Institute at the University at Buffalo, part of the State University of New York (SUNY) network. Charlotte’s Web product categories include full-spectrum hemp CBD oil tinctures (liquid products), CBD gummies (sleep, stress, exercise recovery), CBD capsules, CBD topical creams and lotions, as well as CBD pet products for dogs. Through its vertically integrated business model, Charlotte’s Web maintains stringent control over product quality and consistency. Charlotte’s Web products are distributed to more than 14,000 retail, over 8,000 health care practitioners, and online through the Company’s website at

Charlotte’s Web is a science-driven and a socially and environmentally conscious company. It is committed to using business as a force for good and a catalyst for innovation. Charlotte’s Web donates a portion of its pre-tax earnings to numerous charitable organizations in support of the greater good.

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This skeptic tried CBD to treat anxiety and became a believer

At a time when wellness trends come and go faster than you can say “Goop,” I tend to limit my interrogation of them to a passive observance of headlines. If I see a headline for Himalayan salt tequila shots, the most I’ll do is chuckle to myself—you won’t find me clicking into the article to learn more about Himalayan salt-rim wellness. When I started hearing about people using CBD oil to treat every condition under the sun—from acne to anxiety—I had my usual reaction, which is to glance and move on. But the CBD trend turned out to have some staying power, and I started learning more about it outside of clickbait headlines. Finally, I decided to try CBD to see if it could help with my anxiety issues. And after testing CBD, or cannabidiol, for a few weeks, I’m a convert, because using CBD for anxiety really did help me.

Part of the reason I don’t necessarily pay attention to passing fads, I think, is because I grew up in a small town in southern Oregon called Ashland, where people really do walk around wearing nothing but thongs and dreadlocks in the summertime. We didn’t necessarily come into contact with mainstream trends, even if people did try alternative medicines frequently. And as you can probably imagine, marijuana was also grown and consumed freely in the community.

In 2005, the state passed a law allowing medical marijuana cardholders to grow up to six mature marijuana plants and 18 immature plants on their properties, so it wasn’t uncommon to go to a friend’s garden and find a marijuana plant next to the tomatoes. While the rest of the country still largely treated marijuana as a highly criminalized gateway drug, Oregon was toking up. All of that to say that I’m in no way unfamiliar with the medicinal benefits of marijuana.

The same reason why I stopped smoking, ironically, was the same reason why I now feel passionately about the benefits of CBD.

Marijuana eventually started wreaking havoc on my mental health. In college, after I’d moved to the East Coast, had much less access to weed, and much lower quality weed (the rumors are true), I started finding myself having negative reactions to it. On the rare occasion when I did smoke, I felt paranoid and trapped in negative thoughts that sometimes scared me. Around the same time, I began to seriously struggle with depression and anxiety. To combat my anxiety, I started taking Lexapro, which I pair with various other practices to improve my mental health.

My anxiety doesn’t ever really leave me; it’s not the type of condition that comes and goes in waves. It’s more like a scale. I follow a mental health advocate and businesswoman named Jen Gotch on Instagram, and she uses the scale methodology to describe her depression/mood. If my level of anxiety were on a scale of 1 to 10, I’d say that most days I fall at a 4.8. On the best days, I’m probably around a 1.5, and on my worst days, which are rare, I can be a full-blown 10. What this means is that I get through my days using techniques that therapists, yoga instructors, and Oprah have taught me: deep breathing, taking a second to bring awareness to my body, calling my mom, staring at trees, and talking myself out of negative spirals.

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When I first took CBD a couple of weeks ago, I didn’t feel anything.

I took 28 mg of Charlotte’s Web extra strength hemp extract oil, which comes in a mint chocolate flavor. I was sitting on the couch and, like anyone who has ever taken an unfamiliar substance (legal or not), I felt a sense of excited anticipation while I waited to feel the effects of this magical oil that I’d heard so much about. Of course, my friends told me that you don’t feel high when you take CBD, but I thought that I might feel somewhat of a body high. I didn’t, so I asked my roommate and she gave me this sage advice: “Notice how you don’t feel.” I then scanned my body and realized that my stomach didn’t have that little flutter that I’m so accustomed to. Still, I wasn’t too impressed by that first trial or by CBD oil. Until I experimented more later.

The first time I felt the positive effects of CBD was on a day when my sketch comedy group had a show. I had woken up early to get into Manhattan (I live in Brooklyn), and the regular train I take wasn’t running—this isn’t a huge surprise for anyone who lives in N.Y.C.—but I also still had a long to-do list with stressful tasks, like memorize lines, pick up props, make sure everything goes smoothly. I took a dropper full of Charlotte’s Web’s maximum strength 60 mg CBD oil, but I didn’t instantly feel a change. It wasn’t until I was running around Midtown on the hunt for a flash drive with just 10 minutes until tech rehearsal that I really noticed a difference. My breathing wasn’t shallow, my shoulders weren’t locked up to my ears, and I was actually kind of having fun running down the street in Midtown.

Anyone who’s ever lived in New York can tell you that if you’re enjoying Midtown, you’re probably on drugs, and I kind of was, so that’s fair. But actually, CBD does not get you high.

Now that I’ve learned to use CBD in my daily life, I can attest that the hype is real. For me, anyway.

It’s likely not what you’d expect from anything that’s made from the plant that contains THC, so know that up front if you’re looking to try it yourself. I take CBD now on days when I can feel my anxiety edging towards a 6 or 7 on my scale, but it likely wouldn’t help much on days when I’m at an 8 through 10. But that’s perfect, because I feel like CBD helps me to cope with my anxiety better on normal days. I still take Lexapro, and I don’t think that CBD could necessarily replace that SSRI, but I do feel like it’s a little extra help on days when I need it. When my body feels more relaxed, my mind feels a little bit clearer; it doesn’t have to constantly notice the tension I feel while juggling 20 different self-sabotaging thoughts. It’s almost like CBD eliminates a factor in the anxiety equation, and if your body can relax, you have more bandwidth to deal with your mind’s thought spirals.

Science backs this up to some extent. A large-scale, long-term human clinical trial on the use of CBD to treat anxiety has not yet been conducted, but smaller short-term studies have shown positive effects. I will continue to take CBD oil, either one or two times a day (as the type I use suggests), and I am happy to announce that I’ve finally jumped on one train that L.A. wellness influencers endorse. If you’re curious about CBD for anxiety, talk to your doctor.