How long does cbd oil effects last for dogs

How Long CBD Stays In Dog’s System: How Long To Work & See Results?

These are three of the most common questions dog parents have about CBD for dogs. First off, the answers are not as straightforward as you might think. Several variables affect how fast or slow dogs absorb CBD and how well it works once it’s inside your dog’s body.

This post breaks down everything you need to know about CBD’s interaction once it’s in your dog’s system. From how long it lasts, factors affecting working effectiveness, and how results vary depending on certain variables. Let’s get started!

What Is CBD?

CBD has become extremely popular nowadays. But, the term CBD gets thrown around by people without knowing much about it.

According to Grand View Research, the global CBD market size was valued at $2.8 billion in 2020 and is expected to expand to $13.4 billion from 2021 to 20281. CBD is here to stay. So what is it?

CBD is short for cannabidiol. It is the second most prevalent of the active ingredients of cannabis (marijuana).

It is derived directly from the hemp plant, which is a cousin of the marijuana plant. While CBD is a component of marijuana, by itself, it does not cause a “high.” According to a report from the World Health Organization, “In humans and animals, CBD exhibits no effects indicative of any abuse or dependence potential… to date, there is no evidence of public health-related problems associated with the use of pure CBD.” 2,3

Many people have used CBD products for their pets because of their anti-inflammatory properties, cardiac benefits, anti-nausea effects, appetite stimulation, anti-anxiety impact, and even possible anti-cancer benefits 4 .

How Is CBD Absorbed By Dogs?

As more people use CBD products for their dogs, it’s important to understand how pets absorb them.

Below are some common delivery methods for dogs, they are absorbed, and which CBD product type has the fastest absorption rate.

  • Tinctures (oils): These are often referred to as CBD oils for dogs. They usually come in a bottle with dropper and are typically administred orally by placing a dose under your pet’s tongue, into their throat, or on their favorite food. When given sublingually (under the tongue), it’s absorbed through your pet’s mucosa. CBD oils have the fastest rate of absoprtionand efficacy because the oil enters the bloodstream directly when applied orally.
  • Treats: Just like humans who want to take CBD in the tastiest way possible, pets love CBD treat too. Because CBD treats have to be digested in the stomach and liver, this prolongs the time of absorption and the time it takes for CBD to have an active effect. In other words, CBD treats take longer to absorb and experience results than the oil method.
  • Topicals: Some of the most popular categories of CBD products for pets are topicals (i.e, pet CBD shampoos, sprays, balms). Topicas are absorbed it through their skin. But, contrary to other CBD oil and treats, CBD topicals does not penetrate deep enough into the skin to pass through blood-brain barriers and enter the bloodstream. However, it does provide localized effects when applied through topical means since it absorbs through the pores and hair (fur), working with the CB2 receptors underneath the skin and hair follicles. 19

How Long CBD Takes To Enter A Dog’s Bloodstream

Generally speaking, CBD is absorbed into the human bloodstream within 20 minutes to 2 hours, depending on the method of delivery7. Other factors like the dosage, type of CBD, consistency, dog size, and quality can also play a role in how quickly your pet begins to feel the benefits of CBD.

With that being said, keep in mind that how long it takes for CBD to work will vary dramatically between oils, treats, and topicals.

This brings us to our next question. You are probably wondering which CBD product provides the fastest results.

How Long Does It Take For CBD to Work On Dogs?

How long it takes for CBD to work on dogs depends on the type of CBD product and the treated condition.

According to Honest Paws (a well-known pet CBD oil manufacturer), how long until CBD Dog Treats work will depend on factors such as type of health condition, breed, and body weight. CBD edibles are absorbed through the stomach and could take between 45-90 minutes to work. CBD oil that has been administered sublingually (under the tongue) will take 20-60 minutes to kick in. CBD topicals (creams, shampoos) take about the same time as oils to take effect.

Remember to be patient when giving your dog CBD. For some dogs, the effect of CBD oil kicks in quite quickly. For others, it can take a bit longer for the results to show. It’s also important to give your dog CBD regularly to see results.

How Long Does CBD Stay In A Dog’s system?

How long CBD stays in your dog’s systems largely depends on the CBD concentration being administered. However, other key factors also play a role. We cover those later in this section.

Before we get to the nitty-gritty, you must understand the term “half-life.” In simpler terms, the half-life is the time required for half of the drug to be metabolized and eliminated from the body. 14 For example, if the half-life of a given drug is 2 hours, then, we can estimate this drug will be out of your dog’s system in 4 hours.

So, what is the half-life of CBD oil for dogs?

A few studies can help us understand how long CBD lasts in a dog’s system. One study proved that CBD administered (45 and 90 mg doses) through an IV has a half-life of 9 hours. 16

Another study in 2019 showed that administering CBD, with a CBD concentration of 2mg to 10mg, resulted in a half-life of 4 hours. 20 Another study on the clinical efficacy of cannabidiol treatment in osteoarthritic dogs revealed the half-life of CBD was 4.2 hours. 17 This last study used a CBD concentration of 2 and 8 mg.

Based on the evidence, we can conclude that CBD has an average half-life of 4 hours when the CBD concentration is 2 to 10 mg. So, we can expect CBD to stay in your dog’s system for 8 hours based on that concentration.

However, that range doesn’t apply to every dog on CBD. The time CBD remains in your dog’s body will vastly be affected by the CBD concentration in your treats, oils, or topicals. A clear example of this is the study where they administered a CBD concentration of 45 to 90 mg through an IV (9-hour half-life). The larger concentration meant a longer half-life; hence the longer it would take for the CBD to be out of the body. In this case, it would probably take 18 hours to be out of the dog’s system.

To simplify this even further, if you administer 5mg of CBD oil to your dog. Based on the research above, it will take roughly 8 hours to be out of your dog’s system. If you administer 20mg, you would expect CBD to last longer than 8 hours.

CBD Oil Half-Life & Dosage In Dogs

Understanding the half-life of CBD is key for manufactures and dog owners because it helps them determine the correct dosages.

As a dog owner, you want to know when CBD is out of your dog’s system so you can safely administer the next dosage.

The Journal of Medical Chemistry explains, a short half-life “may require more frequent dosing to maintain desired exposures and avoid unnecessarily high peak concentrations.” 15 Why does this mean? Shorter half-lives mean the substance is out of the system a lot quicker and requires more frequent dosing to keep the effects going.

On the other hand, an overly long half-life can create a prolonged “accumulation and subsequent elimination,” This means a substance with a long half-life will typically last a lot more in the body, which may pose accumulation problems if frequent dosing occurs and/or affect interaction with other substances in the body.

Most pet owners advocate for an eight-hour dosage, which is a good rule of thumb because it aligns with what research indicates regarding CBD duration in your dog’s body.

However, when and how much CBD will depend on the purpose of your dog’s CBD treatment. To better understand the dosage and better assess how much CBD your dog really needs, read our CBD dosage for dogs guide.

Factors That Affect How Long CBD Stays In Your Dog’s System

Every dog and breed is different. The amount of time the CBD stays in your dog’s system depends on several elements.

Here are some factors that will determine how long CBD will stay in your dog’s body.

1. Method of Intake (CBD Type)

There are many ways to consume CBD. Each of these methods has a different result on how much and how quickly CBD gets absorbed into your bloodstream. 8 This is called bioavailability. Understanding this is key in figuring out which CBD product is best for your dog to see the fastest results, as each type of CBD product takes different amounts of time before starting working.

The quickest and most bioavailable way for dogs to feel the benefits of CBD is a sublingual oil or tincture, followed by ingestible products like treats or capsules, and then topicals 9 . Why is this?

  • Oils (tinctures):CBD oil avoids first-pass metabolism by going straight through the capillaries under your tongue. This makes it the most effective method of delivery for pets, which means they’ll feel it quicker.
  • Treats, Pills, and Capsules: Because CBD treats, pills, and capsules have to travel through your dog’s digestive system, they have what’s known as a first-pass metabolism. This means that it’ll take longer to feel the effects of the CBD, or in medical terms – the bioavailability rate.

2. CBD Quality & Type (Full Spectrum vs Broad Spectrum vs Isolate)

There are three main types of CBD that you’ll hear about.

  1. Full Spectrum CBD Oil: Full-spectrum CBD contains small amounts of all components of the cannabis plant. That means it can have trace amounts of tetrahydrocannabinol (THC). Federally legal full-spectrum products will always have less than 0.3 percent THC.

2. Broad Spectrum CBD Oil: This type of CBD does not contain THC. It does contain other components of the cannabis plant so that it won’t be 100-percent CBD alone. Consider it the middle child of the three CBD choices.

3. Isolate (CBD): This is a pure CBD product. Isolate contains no other compounds found in cannabis except for the CBD itself.

Many pet owners choose full-spectrum CBD because their pet may get what’s known as the entourage effect 10 . The entourage effect says when multiple components of cannabis work together, the benefits are substantially better. If you want to maximize the benefits of cannabis, full-spectrum CBD might be your best option.

3. Biology

Body Weight:

Like most cannabinoids, CBD is fat-soluble. Dogs who weigh more tend to have more fat cells in their body. This means that they’ll absorb and store CBD for longer periods of time in their body. Dogs with more fat cells in their body will most likely need more time to adjust. Another thing to think about is the higher your dog’s body mass, the longer it takes for CBD to work. 11


While a dog’s metabolism does include burning calories, it also affects how his body breaks down. 12 Metabolism can function at different rates depending on age, lifestyle, digestive system, and genetic composition. This is what we call a metabolic rate – and every dog has a different one.

If you have an active dog with a high metabolism, they’ll likely feel the effects come on faster; but it will also wear off more quickly. On the other hand, if they have a slow metabolism, you’ll notice that it takes longer to feel CBD coming on; and it will stay in their body for longer.

Endocannabinoid Balance

CBD is part of a unique set of compounds called cannabinoids. These compounds interact with a biological system found in almost all animals. It’s called the endocannabinoid system (ECS), and its cannabinoid receptors are found throughout the entire body. Research suggests that the ECS is responsible for many biological functions like mood, sleep, appetite, and pain response. 13

If your dog’s ECS is imbalanced, he could experience a large range of negative symptoms as a result. While this subject is still being researched, CBD could help to alleviate these symptoms by attaching to the receptors and rebalancing your pup’s system. The more the endocannabinoid system is imbalanced, the longer it will take to feel the effects.

4. Dosage & Potency

The amount of CBD your dog takes every day will affect how fast he feels the effects. In general, the more they are taking, the quicker they’ll feel it. So how much CBD should you give your dog? Choosing the right CBD dose for your dog can feel overwhelming. First off, each company’s dosing guidelines can vary widely because the concentration of CBD differs in the products they make. The dosage can also differ depending on the ailment you’re trying to treat. For example, higher doses are typically needed for more serious health conditions and lower doses for occasional anxiety or general well-being.

The best advice we can give you is to start small and ease into the manufacturer’s dosing guidelines for their specific products. Companies that formulate their own high-quality CBD typically give you detailed instructions on how to dose their various products.

5. Frequency & Consistency

For some dogs, the CBD benefits come right away. You may notice that they’re experiencing less stress or less pain after just one dose of CBD. Other owners may not notice any signs of improvement for a few weeks. If this happens to you, don’t give up and be patient!

Seeing positive results may come gradually. People can get impatient and give up after a few CBD doses because they think it doesn’t work. The key to getting the most benefits out of CBD is consistency! A consistent, daily dose can eventually restore balance to your pup’s ECS, and you’ll be glad you stuck with it.

How Long Do The Effects of CBD Last On Dogs? When Will I See Results?

It varies based on the same factors that influence how long CBD stays in your dog’s system.

Form, dosage, and body composition all play a role in determining how fast CBD kicks in, lasts and what effect it has on your pet.

There is no one answer to this question, as many dogs need CBD for different reasons. For instance, anxiety-related CBD oil typically takes anywhere from thirty to sixty minutes to start up and calm your dog. So results are almost immediate, you could say.

On the other hand, if your dog needs CBD for pain or inflammation-related issues, it may take up to 1 to 2 weeks to get constant, optimal results. For more serious conditions like cancer, arthritis, and chronic pain, you may start seeing results in 2 to 4 weeks.

The effect of CBD usually lasts and provides relief for up to 8 hours.

However, this number varies, as we explained in the section above. The effects are most noticeable during the first hours after absorption. After CBD has exited your dog’s system is time for another dose. Frequency and proper dosing are key for long-term results.

As we know, dogs can consume CBD sublingually or through food. These methods of consumption can very well affect how long your pet experiences relief from the CBD supplement. If you’re applying the oil directly to your dog’s mouth or gums, you should allow 20-60 minutes for it to begin working. When you drop CBD oil into your dog’s food, allow up to ninety minutes for it to begin to work.

Dogs That Should Not Consume CBD

CBD in dogs is known to be well tolerated. The biggest concern is any possible interaction between CBD and other medications 18 . CBD can affect the metabolizing of the other medications in your dog’s system. This can alter the effectiveness of these other drugs, either by enhancing their activity or hindering the desired activity. Studies with humans have shown that this interaction has impacted drug concentrations in the blood.

These medications are blood pressure medications, cholesterol medications, anxiety drugs, antihistamines, corticosteroids, and antibiotics. On the bright side, other medications can have an enhanced effect when combined with CBD. Anti-seizure medications may be more effective, for one. CBD may also give pain relief, allowing users to rely less on NSAIDs and opioids. Also, when CBD was combined with chemotherapy, cancer treatments were more effective. However, you should always address these issues with your vet before treating your pet or combining medications with CBD.

Frequently Asked Questions

Anywhere up to 8 hours.

CBD edibles are absorbed through the stomach and could take between 45-90 minutes to work.

CBD remains in your dog’s system for approximately 8 hours when the CBD concentration is between 2 to 10mg.

Anywhere from 2-4 weeks

CBD Effectiveness & Benefits

CBD drops for dogs or CBD dog treats can ease several conditions your pup may suffer from either occasionally or chronically, including anxiety, stress, moderate to severe pain, chronic inflammation, arthritis & joint pain, digestion problems, nausea, symptoms from cancer, and more.

To learn all about CBD oil for dogs, the benefits backed by science, and the best CBD oil product in the market, be sure to read our reviews of the best CBD oil for dogs and the best CBD dog treats.

How Long Does CBD Stay in a Dog’s System?

It’s important we as pet owners do everything we can to ensure our dogs have the happiest and healthiest lives possible. After all, a dog’s job is to play and provide companionship.

How often have we thought about how we can either maximize our dog’s quality of life, or help them maintain the quality of life they currently have? If there’s anything we can do to make our dogs happier and help them thrive, we’re definitely going to do it.

One thing that has been critical in providing better care for our dogs is the availability of better and more affordable pet care, and the increasing availability of total wellness products and supplements to help support our dogs’ overall health. Just like we as humans can benefit from creating a health stack that includes proper nutrition, diet, exercise, and supplements, your dog can benefit from these measures too.

When considering supplements for your dog, you should always speak with your veterinarian to determine if the supplement you’d like to give is appropriate for your dog.

All dogs are different, and each will react differently to different supplements. Speak to your veterinarian and voice your concerns, discuss other medications or treatment plans your dog may be undergoing, and the potential benefits of supplementation. These are all important aspects of deciding if you should give your dog a particular supplement.

What is CBD?

A great supplement that is relatively new in terms of supplementation for canines is CBD. Cannabidiol, or “CBD,” is an all-natural chemical compound found in the leaves, flowers, and stems of the cannabis-sativa plant. The cannabis-sativa plant contains over one hundred of these cannabinoids, which can be taken to help support overall health and wellbeing, and support certain systems in our dog’s physiology.

CBD is typically extracted in an oil form, and this oil can be delivered in isolate, broad-spectrum, or full-spectrum formulas. Isolate oil delivers only CBD oil–no other plant parts are included, which is why isolate oil cannot deliver the “entourage effect.” The entourage effect refers to all compounds of the cannabis-sativa plant working together synergistically to provide the most benefit that the plant can offer. You can only find the entourage effect in a full-spectrum CBD oil.

To quell any fears you may have about CBD oil being intoxicating to your dog, you should know that CBD is a non-psychoactive cannabinoid. Unlike tetrahydrocannabinol, or “THC,” CBD does not get your dog “high” or make them feel impaired. In fact, for CBD to be legally distributed, it must contain less than .03% THC. It’s important that a trace amount of THC is included, however, so the entourage effect can be achieved.

How does CBD React with Your Dog’s Body?

CBD is generally well tolerated by canines, and very few side effects are reported from owners of dogs who are given CBD and CBD products.

CBD interacts with systems in your dog’s body that are responsible for things like mood, sleep, appetite, and memory. CBD is a great supplement to give your dog for:

  • Healthy GI function. CBD helps support happy tummies, so if your dog suffers from occasional gastric upset, CBD can help provide much needed temporary comfort and help maintain your dog’s natural gut flora.
  • Healthy brain function. CBD helps support cognitive function in dogs and gives them essential fatty acids that promote healthy brain function.
  • Joint and mobility support. We want our dogs as mobile and as happy as possible, for as long as possible. CBD supports joint and cartilage health which can help your dog maintain their mobility.
  • Temporary environmental stress alleviation. Dogs that are stressed by everyday environmental factors can benefit from CBD’s soothing benefits. CBD promotes calmness and relaxation for better emotional balance.

Factors that Affect How Long CBD Stays in a Dog’s Body

Every dog and breed is different, and the length of time that CBD will stay in your dog’s body depends upon many factors. As such, it can be difficult to determine how much CBD to give your dog and how frequently.

Here are some factors that will determine how long CBD will stay in your dog’s body.

  1. Weight
  2. Diet
  3. Activity level
  4. Your dog’s own biochemical makeup
  5. Frequency of CBD dosing

While it may seem as though getting the right amount of CBD into your dog is very complicated, it’s really just a matter of experimenting with the recommended dosing and developing a system that works well for your dog. You’ll know you’ve found the right amount when your dog responds positively to treatment.

You can give VETCBD’s CBD oil tincture directly to your dog, as our CBD oil is formulated with high-quality olive oil, which helps a dog’s body better absorb CBD quickly and with less breakdown in the first parts of digestion.

How Frequently Should You Give Your Dog CBD?

It’s first important to decide how much CBD you will give your dog.

For VETCBD’s hemp oil tincture , a dosage of .2mg of CBD per pound of bodyweight is a good median amount of CBD that is well tolerated and effective. However, achieving this dosage will depend on the delivery method of the CBD you choose.

You may need to dose your dog with CBD oil more than once daily, but determining how frequently your dog needs CBD will also depend on the factors listed above (i.e. weight, diet, activity level, etc.). The best option is to begin with a small dose and see how your dog responds to it. If your dog seems unaffected or non-responsive to the CBD treatment, consider a second dosage after 12 hours has passed since the first dose.

How Long Do the Effects of CBD Last?

When we discuss how long a supplement lasts in your dog’s body, we are referring to that supplement’s “half-life.” Half-life refers to the amount of time it takes for the concentration of the supplement to decrease by half the amount that was originally given.

The half-life of CBD in dogs is about four hours, which means CBD can be present in a dog’s system for twenty-four hours, but it may need to be present at a certain level to achieve desired benefits.

This means that even though you gave your dog 2mg of CBD in the morning, and you know it will be present in their system through evening, the amount of CBD present in their system by the end of day may not be enough to give them the desired amount of temporary comfort they need.

If you are giving your dog CBD oil as an overall addition to their health stack, they may only need one dose per day. Other dogs may need twice a day dosing, especially if being used to help promote relaxation. Again, it depends on your dog’s physiology and metabolic rates.


CBD oil is a great supplement for supporting your dog’s overall health and wellness and giving them comfort when they need it the most. CBD will remain in your dog’s system for up to twenty-four hours, but depending on the dosage amount, the severity of your dog’s symptoms, and his own physiology, your dog may need more or less than a full recommended daily dose of CBD.

It’s important to always speak to your dog’s veterinarian prior to starting any new supplementation routine, including CBD oil supplementation, to make sure it’s a good fit for your specific pup’s health profile.

How long does CBD oil last in dogs?

Now that you’ve discovered all of the wonderful benefits of CBD oil for dogs, naturally, you have questions that you need to be answered before you administer CBD dog treats to your canine. Perhaps some of the most common questions that pet parents have regarding CBD oil are: How long does the effect of CBD last in their dog? How much time does it take for CBD oil to begin working? It is important to know exactly how long CBD will last in your pet’s system so that you can ensure the maximum relief for your pet’s health condition. You can also find a lot regarding the use of cbd for dogs on this site.

Most of the research available regarding how cannabinoids are processed in the body is based on the human’s interaction with the substance. However, both humans and dogs have an endocannabinoid system that functions in a very similar manner to process CBD. You can navigate to this site for more information on the endocannabinoid system and how it processes CBD.

What Happens in Your Dog Body When CBD Is Administered?

As previously mentioned, both humans and dogs have what’s called an endocannabinoid system. It is a molecular system that balances and regulates several functions in the body including; immune response, metabolism, appetite, and mood just to name a few. The earliest research findings were revealed in the sixties when the ECS was initially discovered.

When a dog is administered a dose of CBD oil it has immediately linked to the endocannabinoid receptors. It can begin to fight off any infection and regulate different functions. In turn, it can alleviate any pain, anxiety, and seizures. Due to its never-ending benefits, many pet owners are turning to CBD for cats and dogs for their health related issues.

How Long Will CBD Last in Your System?

Traces of cannabinoid can last in the body for several weeks after CBD has been consumed and the effects of the super. Generally, it can take up to a week to pass through the dog’s body. However, how long CBD stays in a dog’s system depends on key factors like:

  • Bodyweight
  • Diet
  • The dose of CBD administered
  • Activity level
  • Unique chemical makeup

Also, how often you are administering CBD to your pet determines how long it stays in their system. For instance, for a single dose of CBD, it can stay in your dog’s system for up to three days. On the other hand, if you were giving your pet CBD daily it can take ten or more days for it to get out of your system.

How Long Can I Expect the Effects of CBD to Last?

Determining the perfect dose for your pet can take some time. Once you know how much CBD your dog needs to get relief from their symptoms it can take about thirty to forty-five minutes before they begin to feel the therapeutic effects. How long does it last?

For dogs with anxiety conditions, it can take at least sixty minutes before they feel calm. On the other hand, if your dog is dealing with joint pain or some other type of inflammatory pain condition, they will begin feeling some relief within 30-60 minutes.

CBD can be consumed sublingually or through food. These methods of consumption can very well affect how long your pet experiences relief from the CBD supplement. If you’re applying the oil directly to your dog’s mouth or gums you should allow 20-60 minutes for it to begin working. When you drop CBD oil into your dog’s food, allow up to ninety minutes for it to begin to work.

Generally, CBD can provide relief for six to eight hours. If you notice that the effects of the CBD are wearing off faster than usual you should increase the dosage to maintain the same results.