Is cbd oil effective for crohn’s

Best CBD Oil for Crohn’s Disease – May 2022

Can CBD oil help with Crohn’s disease, and if so, how?

  • Crohn’s disease is a prevalent inflammation of the digestive tract that is often recognized by symptoms of abdominal pain, severe diarrhea, malnutrition, fatigue, and weight loss. It is a common type of inflammatory bowel disease (IBD), affecting more than 3 million Americans in 2015 (1 ) .
  • Despite having no cure, doctors have developed therapies that may alleviate the symptoms of Crohn’s disease, allowing patients to function normally (2 ) .
  • One particularly promising treatment is CBD (cannabidiol), a compound from the Cannabis sativa plant that supposedly has several therapeutic applications (3 ) .
  • Several studies have shown that CBD can inhibit intestinal inflammation, provide pain relief, and improve the overall quality of life for patients with IBD (4-6 ) .
  • As with any medication, it is in the best interest of people to consult a doctor before incorporating CBD into their regimen.

Why Some People Are Turning to CBD for Crohn’s Disease

Crohn’s disease is an inflammation of the digestive tract characterized by severe diarrhea, abdominal pain, weight loss, malnutrition, and fatigue. It is one of the most common types of inflammatory bowel disease (IBD) that affects more than 3 million American adults in 2015 (7 ) .

The disease is often associated with a decreased quality of life and frequent complications that require hospitalization and, sometimes, surgical procedures. Although Crohn’s disease has no cure, there are several therapies available that may reduce its symptoms and allow patients to function well (8 ) .

CBD, also known as cannabidiol, may be a promising therapy for people with an IBD , such as Crohn’s disease. CBD is one of the primary compounds of the cannabis plant that, according to research, has several therapeutic applications (9 ) .

Researchers of a study in 2011 found that CBD might inhibit inflammation in the intestine of mice with ulcerative colitis, another common IBD. They also learned that the compound reduced intestinal damage by counteracting the inflammatory environment caused by the disease (10 ) .

Another study on rats with colitis has shown that CBD, together with THC (tetrahydrocannabinol), was able to reduce inflammatory markers in the subjects (11 ) . THC is also another chemical compound obtained from cannabi s (medical marijuana). THC is often used together with CBD for medical conditions.

The study further showed that this combination of compounds lowered the occurrence of colitis symptoms . Scientists learned that CBD enhanced THC’s effects in alleviating the inflammatory bowel disease in rodents (12 ) .

A study in 2012 showed that applying CBD topically to mice with colitis led to significant improvement in the subjects’ health conditions (13 ) . Meanwhile, rodents in another trial were given CBD orally to treat colitis, resulting in the reduction of injury and bowel movement commonly linked to IBD (14 ) .

The studies mentioned were performed on animals. Further research would be necessary to see if the same outcomes can be obtained from studies conducted in human subjects.

Additionally, CBD is reported to engage with a re ceptor kn own as GPR55, which plays a vital role in intestinal inflammation (15 ) .

Scientists believe that the endocannabinoid system (ECS), which is in charge of numerous body functions, is a potential therapeutic target for treating IBD. They also think that its compatibility with cannabinoids , like CBD , is how these compounds bring about their therapeutic effects.

How CBD Oil Works to Help with Crohn’s Disease

The ECS assumes a crucial role in controlling many fundamental functions of the body. It also affects the gastrointestinal tract (GI tract) by managing gut homeostasis and movement (16 ) .

In people with Crohn’s disease, the ailment interrupts the ECS receptors designed to ensure efficient gastrointestinal operations. These chemical structures are expected to protect the gut by preventing the formation of inflammation and reducing intestinal motility.

One of the main goals of the ECS is to promote balance in the body, primarily through its CB1 and CB2 receptors. CBD, being a cannabinoid that is compatible with these structures, may help in accomplishing this objective.

Scientists believe that dosing with CBD can stimulate the cannabinoid receptors in charge of anti-inflammatory effects (17 ) . By activating these chemicals, cannabis products , like CBD oi l , may inhibit inflammation and provide pain symptom relief.

This reduction in inflammation should contribute to regulating gut pain and irritation while normalizing bowel movement – all of which are clinical signs associated with Crohn’s disease.

The Pros and Cons of CBD Oil for Crohn’s Disease

The Pros
  • Cannabinoids , like CBD , interact with the ECS to bring about their purported therapeutic benefits, one of which is providing balance in the digestive tract .
  • CBD has anti-inflammatory properties, which scientists believe can reduce the common symptoms of IBD.
  • According to a study, cannabinoids, such as CBD, may alleviate abdominal pain and diarrhea, two common symptoms of Crohn’s disease (18 ) .
  • CBD is a natural compound acquired from the cannabis plant. It does not have mind-altering effects, unlike THC.
  • The United States Food and Drug Administration encourages and supports scientifically-based research on CBD (19 ) .
The Cons
  • There is a distinct lack of human clinical trials on CBD for Crohn’s disease, as most of the studies were conducted on rodents.
  • Some of the animal studies show inconclusive results on CBD’s efficacy for IBD.
  • The FDA does not approve a marketing application on cannabis products for treating any disease or health condition (20 ) .
  • Epidiolex is the only CBD product that the FDA allows . It is a prescribed drug for treating two rare forms of epilepsy (21 ) .

How CBD Oil Compares to Alternative Treatments for Crohn’s Disease

Herbal treatments , like aloe vera juice, chamomile, and peppermint , are said to ease the symptoms associated with IBD. Meanwhile, probiotics may help in increasing the naturally good bacteria in the gut and restore balance (22 ) .

Naturopathic therapies involving dietary changes are also said to successfully manage IBD, including Crohn’s symptoms (23 ) .

Meanwhile, studies on CBD have shown that the compound contains properties that might help in alleviating chronic pain and fighting inflammation.

Today, CBD products are mixed with aloe vera, chamomile, peppermint, and other herbs to bring about the maximum effect in counteracting the symptoms of Crohn’s disease activity. CBD infused with probiotics are also popular in helping maintain a healthy intestinal tract.

How to Choose the Best CBD Oil for Crohn’s Disease

There are three main types of CBD products that people can consider in easing IBD and Crohn’s disease symptoms.

Full-spectrum CBD contains all of the chemicals present in cannabis , including varying amounts of THC. These usually are sold as CBD tinctures, vaping oils, creams, and edibles.

According to federal law, this type of CBD is only allowed to have a maximum of 0.3% THC content.

Meanwhile, broad-spectrum CBD also has the compounds of cannabis except for THC. The psychoactive compound is removed to cater to individuals who do not wish to consume it together with their CBD.

Finally, there are CBD isolates that are made of pure cannabidiol. These are often obtained from hemp plants and do not contain the other compounds of medical cannabis .

Users should seek medical advice from a doctor before deciding to use CBD for Crohn’s disease.

  1. Buy high-quality CBD products only and find legitimate brands that sell them. Most reputable companies grow their hemp or purchase them from reliable producers.
  2. Read up on product reviews before buying from an online shop. If they are a physical store or dispensary, check whether the store is allowed by the government to sell.
  3. Compare company claims with third-party lab reports by obtaining a certificate of analysis (COA) for each CBD product purchased.
  4. Be aware of the precise legal stipulations associated with CBD use in the area where one is going to buy and consume the extract.
  5. Look for certification codes for CBD products. There are certification authorities that approve only certain CBD goods after they have undergone thorough screening tests.

CBD Dosage for Crohn’s Disease

Since CBD is a relatively new medical treatment of Crohn’s disease, healthcare providers are still figuring out the right dosage that is both effective and safe for users. It may be helpful to look at the dosage used in past clinical trials to get the proper amount.

One small study concerning CBD for treating ulcerative colitis had its participants take 50 mg of CBD oil twice each day, increasing the dose to as much as 250 mg. Researchers found that users that took CBD had significant clinical remission and improved quality of life (24 ) .

Additionally, the study revealed that the participants did not experience severe side effects after ten weeks of treatment with cannabis use.

Meanwhile, other health experts recommend a starting dose of 40 mg and gradually increase the amount from there.

Like with any medication, the best advice would be to start at the lowest effective dose and gradually increase this as needed. Keep in mind that lower doses often have lower side effects compared to higher ones with increased risk.

How to Take CBD Oil for Crohn’s Disease

  • CBD capsules and pills – Studies done on using CBD capsules for IBD have shown improved quality of life in the human subjects consuming the product daily.
  • CBD edibles – These CBD products may be found as gummies or chocolates. They are ideal for users that have trouble swallowing capsules.
  • CBD oils and tinctures – These are often applied under the tongue and are known to take effect immediately.


Crohn’s disease is an inflammatory bowel disease that is known to affect more than 3 million Americans. This health condition is often linked to a poor quality of life for its patients and regular complications that lead to hospitalization and surgery.

The symptoms that are associated with the disease include abdominal pain, severe diarrhea, malnutrition, weight loss, and fatigue.

Although there is no cure for Crohn’s disease, there are several forms of therapy that could help reduce symptoms and allow IBD patients to function normally. CBD is one promising complementary therapy that, according to research, may alleviate the pain and gut inflammation associated with Crohn’s disease.

However, most of the studies that were made for the disease were carried out on animals. No direct evidence exists that proves CBD is an effective treatment for IBD and Crohn’s disease.

CBD for Crohn’s Disease [Does It Work?]

Medical marijuana is quickly making a big move into the mainstream world. The public support for the legalization of cannabis is increasing rapidly and for very good reason. People are waking up to the fact that cannabis could be the answer to many serious health issues. A recent study found that a staggering 89% of Americans are supporters of medical cannabis.

Crohn’s disease is just one of the many ailments where cannabis could help alleviate the symptoms. Both science and firsthand experiences indicate how CBD helps with Crohn’s disease. This article will cover what Crohn’s disease is, who suffers from it, and how CBD can help. We will also look at ways you can consume CBD for maximum potential therapeutic benefits.

Crohn’s Disease 101

Crohn’s disease is a type of inflammatory bowel disease (IBD). It is a condition that causes inflammation of the gut or digestive system. Although Crohn’s can affect any part of the gut, two of the most common areas are the ileum (the last part of the small intestine) and the colon. Those who have Crohn’s disease suffer from long-term swelling and irritation in the gastrointestinal tract. The result is very painful stomach cramps and diarrhea.

According to the Centers for Disease Control and Prevention, three million people in North America suffer from inflammatory bowel disease. These conditions include Crohn’s disease and ulcerative colitis. Unfortunately, western medication offers no known cure for it, although there are some treatments.

Crohn’s is considered a chronic condition which means that it is ongoing and likely to be life-long.

Crohn’s can result in abdominal pain, severe vomiting (although this is less common), diarrhea and bloody stool, extreme weight loss, and even skin and eye conditions. Anyone who has Crohn’s disease will tell you that it’s a debilitating ailment that causes extreme pain and disruption in day-to-day life.

Also, Crohn’s is considered a chronic condition which means that it is ongoing and likely to be life-long. Those who suffer from the condition may experience periods of good health, followed by times when symptoms are more active or flare up.

The symptoms will vary between individuals, and they often depend on where in the gut the disease is active. These symptoms will range from mild to severe and may change over time. Some of the most common symptoms (along with those we already mentioned above) are the following:

  • Tiredness and fatigue
  • Anemia (a reduced level of red blood cells)
  • Mouth ulcers
  • Loss of appetite and weight loss
  • Feeling generally unwell or feverish

Who Suffers from Crohn’s Disease?

Affecting as many as 780,000 Americans, it’s important to understand who is at risk of developing this disease. Crohn’s can occur at any age, but it tends to onset in adolescents and young adults between 15 and 35. It can affect both men and women, but women are more likely to have Crohn’s disease.

While we do not fully understand the exact causes of Crohn’s, diet and stress appear to be major factors that can aggravate it. Also, the latest research suggests that genetics and a combination of hereditary and environmental factors may contribute to the development of the condition.

The immune system also plays a major role, but it is unclear exactly how. Researchers don’t consider Crohn’s disease an autoimmune disease (in which the body’s immune system attacks itself). Instead, the immune system may be attacking something else, like a virus, in the intestines.

At present, there is no medical cure for Crohn’s disease in mainstream medicine. However, surgery and medication can give long periods of release from symptoms. Unfortunately, pharmaceutical treatments for Crohn’s may have adverse side effects. These could include headaches, vomiting, night sweats, skin diseases, infections, and nausea.

This is where cannabis comes in, and more specifically, CBD. For those who suffer from this debilitating disease, there is hope. CBD is a natural remedy that could provide relief for many medical ailments, including Crohn’s disease.

How CBD Can Help with Crohn’s Disease

Cannabidiol (CBD) is a chemical found in cannabis. Although it comes from the same plant as THC, it doesn’t create any intoxicating effects, meaning it won’t get you high. CBD also has very mild side effects compared to almost all other medications, and it poses no risk of addiction. Thus, it is a great option for patients looking for pain relief – especially those who want to avoid opioids and their adverse effects.

Pharmaceutical medications can help with the symptoms of Crohn’s disease. Unfortunately, some people may feel that the side effects (such as those mentioned above) are too distressing. As research into cannabis intensifies, scientists are discovering how cannabinoids are potentially a less risky way to help patients with Crohn’s disease.

What Does the Research Say?

In an observational study, researchers in Israel monitored and assessed the effects of cannabis use on patients with IBD. One hundred and twenty-seven licensed medicinal cannabis patients took part in the study. The researchers closely monitored these participants using several evaluative measures.

These included methods of consumption and monthly consumption rate, the use of other medications, adverse effects, and the long-term effects of medicinal cannabis use. The authors also measured the exact THC and CBD concentrations these patients consumed.

After undergoing treatment for 44 months, the researchers used the Harvey-Bradshaw Index to evaluate the effects of medicinal cannabis use on patient outcomes. The Harvey-Bradshaw Index score decreased from 11 to 5 (a lower score is indicative of an improvement in the symptoms of Crohn’s Disease). Average daily bowel movements decreased from 7.0 to 3.4. Patients also reported experiencing a significant reduction in pain.

Learn the facts…

Encouragingly, 78% of participating patients reported that they experienced no harmful side effects. Some patients experienced minor side effects, such as a dry mouth and memory decline. However, these patients also stated that the improvement in their symptoms outweighed these side effects.

Naftali et al., who carried out the study, concluded that cannabis use could induce clinical improvement in patients with IBD. The researchers also said marijuana is associated with reduced medication use and weight gain. The researchers noted that these patients responded well to a dose of 30g per month or 21mg THC and 170mg CBD per day.

Ways to consume CBD for Crohn’s Disease

If you decide to try CBD for Crohn’s disease, it is important to remember that you should continue taking all the medications your doctor prescribes. Additionally, discuss any other treatments you are interested in trying (including CBD) with your doctor. If you do end up trying CBD, here are a few of the ways you can take it.


This is possibly the easiest and most precise way to get your daily CBD supplement. It’s a fast and simple answer. It is ideal for people who don’t particularly like the taste of cannabis, the act of vaping, or the process of ingesting raw oils. CBD pills are the #1 choice for busy schedules as they only take seconds to consume.


You can heat and inhale CBD e-liquid through an e-cigarette, vape pen, or vaporizer. CBD e-liquid is also known as vape juice and is specifically made for vaping. This is an important distinction from raw CBD oil, which you ingest by placing it under the tongue and then swallowing.

Ensure your product is free of PG, PEG, and vegetable glycerin and is not an off-market brand that may contain the very dangerous vitamin E acetate.


CBD edibles take a while to affect (usually about 30 minutes but possibly up to 2 hours). However, they present the benefit of longer-lasting effects. CBD edibles are easy to make, and many of the best ones are delicious.

They are a great choice for anyone wanting to combine CBD with their daily diet and nutritional intake. However, as the goal is to decrease inflammation, avoid edibles with inflammatory additives like sugar, high-fructose corn syrup, or vegetable oils.

If you want to give CBD for Crohn’s disease a try, there is no need to worry about smoking it.

There are many ways to consume CBD, including dabbing, which allows for intense potency. However, edibles are by far the most common and most popular product. What matters most is that if you want to give CBD for Crohn’s disease a try, there is no need to worry about smoking it. There are many CBD products available on the market, and it’s all about discovering which one works best for you.

Final Thoughts on CBD for Crohn’s Disease

Researchers must conduct more studies to determine the efficiency and long-term effects of this cannabis-based therapy.

However, with the growing support of medical cannabis, more funds and effort will likely go into conducting additional studies and additional clinical research.

We hope this post proves informative, educational and hopefully cleared up any uncertainties you may have had regarding CBD and Crohn’s disease.