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CBD Oil for Gastritis – May 2022

Commonly prescribed medications and over-the-counter drugs for gastritis include omeprazole, rabeprazole, lansoprazole, dexlansoprazole, esomeprazole, and pantoprazole (6) . These drugs are some of the most potent inhibitors of stomach acid.

However, these medications may have side effects , such as iron and B12 deficiency, increased risk of fractures, pneumonia, and Clostridium difficile infections (7) . They can also be quite expensive over the long-term.

Clostridium difficile infections may cause diarrhea and eventually develop into a life-threatening medical condition .

Doctors may also prescribe antacids to treat gastritis by neutralizing stomach acid and providing pain relief. However, these drugs may result in constipation or diarrhea (8) .

A 2020 study in the International Journal of Molecular Sciences outlined CBD’s role in preventing and treating gastrointestinal disorders, like irritable bowel syndrome (IBS) and gastrointestinal cancer (9) .

The study demonstrated CBD’s anti-inflammatory properties in mice models of intestinal inflammation.

Gastritis is a collective term that refers to the inflammation of the lining of the stomach (10) .

Research in the Journal of Molecular Medicine evaluated CBD’s effects on an inflammatory bowel disease like ulcerative colitis (11) .

The authors found that CBD had anti-inflammatory properties beneficial for the inflamed gut. They also reported that CBD, a “likely safe compound,” prevented experimental colitis in mice.

Despite CBD’s purported health benefits on the digestive tract , it is essential to note the side effects of CBD use. These effects include diarrhea, changes in appetite or weight, and tiredness (12) .

CBD for Inflammation

A 2019 review archived in the journal Antioxidants stated that CBD had anti-inflammatory and antioxidant properties (13) .

The authors also mentioned CBD’s promise in treating disorders associated with inflammation and oxidative stress, such as cancer, cardiovascular, metabolic, and neurodegenerative diseases.

Another study documented in the journal Future Medicinal Chemistry discussed CBD’s effects on non-obese and diabetes-prone female rodents (14) .

The researchers found that CBD had anti-inflammatory effects that could help prevent type 1 diabetes.

CBD for Nausea

Common symptoms of gastritis include nausea and vomiting (15) .

Preclinical research showed that CBD might be useful in treating vomiting and nausea caused by chemotherapy and other treatments (16) .

A study archived in the British Journal of Clinical Pharmacology evaluated the effects of a dose containing CBD and tetrahydrocannabinol (THC) on patients with chemotherapy-induced nausea and vomiting (17) .

The researchers found that CBD and THC were well-tolerated and had antiemetic (vomit-preventing) properties.

They also observed that patients who received the cannabis-based medicine had better protection against delayed chemotherapy-induced nausea and vomiting.

CBD and THC are derived from the Cannabis sativa plant. However, unlike CBD, THC may get individuals high because of its psychoactive properties.

THC mainly comes from marijuana, a variant of the cannabis plant. Despite THC’s suggested benefits, medical marijuana use is not legal in the entire United States (18) .

CBD for Ulcers

Untreated gastritis may result in stomach ulcers and bleeding or stomach perforation (19) .

A 2018 study in the journal Phytotherapy Research evaluated CBD’s effects on oral wound healing (20) .

Standardized ulcers were induced in 60 rats. They were injected with 0mg (control), 5mg, and 10mg of CBD per kilogram of each rat’s body weight daily.

The researchers discovered that CBD had anti-inflammatory effects on the early phase of wound healing. However, they noted that their findings were insufficient to conclude that CBD use could improve oral traumatic lesions.

CBD as a Painkiller Substitute

The regular use of painkillers and nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, may result in gastritis and ulcers (21) .

Meanwhile, s tudies showed that CBD products might have analgesic effects. Hence, they may be used as substitutes for painkillers.

A study published in the journal Postgraduate Medicine revealed that CBD improved chronic pain in participants using opioids for pain management (22) .

One hundred thirty-one patients were included in the study. The researchers found that half of the study sample was able to reduce opioid use eight weeks after adding CBD to their medication regimen.

Participants who used CBD reported improvements in their quality of life. Their chronic pain and sleep quality also improved.

In another research, results indicated that CBD had analgesic and anxiolytic (anxiety-reducing) effects (23) .

Three hundred ninety-seven individuals were prescribed CBD. Participants who had non-cancer pain reported improvements in their pain.

Meanwhile, those who had mental health symptoms experienced alleviation of their depression and anxiety symptoms.

CBD was well-tolerated, and the participants did not report any adverse effects. Other CBD benefits include improved sleep and appetite.

How CBD Oil Works to Alleviate Symptoms of Gastritis

A study documented in the PLOS One Journal evaluated how CBD purportedly reduces intestinal inflammation (24) .

Eighteen participants were included in the study. The results revealed that CBD might interfere with enteroglial-mediated interactions in an intestinal inflammatory environment.

Enteric glial cells make up the enteric nervous system, a regulatory system responsible for gastrointestinal function (25) .

According to the study, CBD was involved in the downregulation of the protein S100B, resulting in reduced intestinal damage during acute and intestinal inflammation.

S100 proteins have a vital role in mediating innate and acquired immune response s (26) . These responses significantly contribute to the development of chronic inflammatory diseases.

It is believed that CBD’s interaction with the endocannabinoid system (ECS) may be related to its anti-inflammatory properties.

The ECS has an essential role in maintaining the body’s natural harmony. To fulfill this function, it interacts with several organs and systems in the body, such as the endocrine and immune systems (27) .

A study conducted in 2019 outlined the role of CBD and the ECS’ cannabinoid receptors in inflammation (28) .

Research found that CBD was a weak agonist of the cannabinoid receptor 1 ( CB1 receptor ) in humans and mice. It also stated that CBD demonstrated inverse agonism of the cannabinoid receptor 2 (CB2 receptor) .

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An agonist is a substance that mimics another substance’s action, stimulating an action (29) .

The researchers found that the activation of cannabinoid receptor 2 reduces oxidative stress and inflammation.

They also found that CBD’s anti-inflammatory activity involved the reduction of cytokine levels, the inhibition of T-cell proliferation, the induction of T-cell apoptosis, and the migration of immune cells.

Cytokines are molecules that direct cell movement to sites of inflammation, trauma, and infection (30) .

T cells contribute to sustained inflammation by producing proinflammatory cytokines (31) .

Apoptosis is programmed cell death vital in removing unnecessary or abnormal cells (32) .

The Pros and Cons of CBD Oil for Gastritis

The Pros
  • Previous studies showed CBD’s positive effects on symptoms associated with gastritis and other conditions related to the digestive system .
  • Compared with conventional drugs prescribed for gastritis, CBD’s safety profile is more favorable (33) .
  • There are no reported cases of human or animal dependence on CBD (34) . Hence, individuals considering using CBD to treat their gastritis should not worry about developing a dependence on the substance.
The Cons
    • Researchers should further investigate CBD’s effects on gastritis.
    • Despite the benefits of CBD , it still has side effects, such as diarrhea, tiredness, and changes in weight or appetite (35) .
    • Policies from the United States Food and Drug Administration (US FDA ) do not support CBD as therapy for medical conditions other than epilepsy.

    How CBD Oil Compares to Alternative Treatments for Gastritis

    A study archived in the Sultan Qaboos University Medical Journal investigated honey’s antibacterial effects on the bacterium Helicobacter pylori ( H. pylori) , the common cause of several digestive issues, such as gastritis and a very common contributor to the development of gastric and duodenal ulcers (36) .

    The researchers concluded that some honey brands had antibacterial properties useful in treating H. pylori infections.

    They also noted that when honey was used with antibiotics, such as clarithromycin and amoxicillin, there was no synergy or antagonism.

    They recommend that honey may be useful as an adjunct therapy. It helps reduce the elimination time of H. pylori bacteria from the stomach lining of individuals with gastritis or duodenal ulcer.

    Similarly, CBD was found to have antibacterial properties. Research in 2019 reported CBD’s efficacy in killing a range of Gram-positive bacteria (37) .

    The researchers suggested that, given CBD’s anti-inflammatory properties and proven safety in humans, the substance held promise as a new antibiotic.

    They also noted how CBD retained its efficacy against bacteria that became highly resistant to other traditional antibiotics.

    Gram-positive bacteria are called such because they give a positive result when put under the Gram stain test (38) .

    How to Choose the Right CBD for Gastritis

    A previously cited study showed the efficacy of THC or medical cannabis on gastritis symptoms, such as vomiting and nausea. However, as mentioned earlier, THC use is not legal in all US states.

    Full-spectrum CBD oil contains all the Cannabis sativa plant components, including terpenes, flavonoids, fatty acids, essential oils, and trace amounts of THC.

    It is suggested that full-spectrum oils provide full therapeutic benefits because of the synergy of all the active ingredients of the cannabis plant. This mechanism is called the entourage effect.

    The THC content of full-spectrum CBD products (less than 0.30%) is allowed by federal laws. However, this minimal amount may still be detected by drug tests.

    Individuals who want to purchase CBD products free of THC may buy broad-spectrum CBD. This type of CBD oil has all the ingredients of the full-spectrum oil except for THC.

    For pure, isolated cannabidiol, CBD isolates may be purchased.

    Full-spectrum CBD oils are recommended for gastritis treatment. Still, individuals are encouraged to speak to a medical professional before purchasing any CBD product.

    It is also essential to research if a manufacturer or dispensary is credible and authorized by the government to sell CBD to avoid buying illegitimate products.

    CBD Dosage for Gastritis

    Currently, no standard dosage chart has been developed for CBD in treating gastritis. However, it is recommended to begin with a small amount of CBD .

    If no adverse effects are seen, the dosage may be increased gradually until the desired effect is achieved.

    Individuals using CBD for gastritis are encouraged to keep a journal of their reactions to the substance. They may refer to this journal during consultations with their physician.

    Before adding CBD to one’s gastritis medication regimen, it is recommended to inform a medical professional first.

    How to Take CBD for Gastritis

    There are several options when taking CBD for gastritis.

    Some formats, such as CBD oils and tinctures (drops), allow individuals to take CBD directly. Tinctures may be applied sublingually, or under the tongue, for added efficacy.

    CBD oils may be mixed with food or beverages to mask CBD’s naturally grassy taste.

    CBD pills, gelcaps, capsules, edibles, and gummies may be ingested. This format also allows people with gastritis to conveniently bring their CBD medication with them anywhere.

    This format is also appropriate for people with gastritis problems who want to take a consistent dosage of CBD.

    CBD topicals, such as balms, salves, lotions, and ointments, may also be used. During episodes of abdominal pain or upset stomach , these topicals may be massaged into the affected area.

    Some topicals contain soothing ingredients, such as peppermint and menthol, for added pain relief.

    For instantaneous effects, CBD may be inhaled via vape pens. However, vaping CBD may be challenging, as it is hard to determine how much CBD was already taken.

    In some individuals, vaping may also cause lung problems (39) .

    Understanding Gastritis

    According to Johns Hopkins Medicine, gastritis occurs when the stomach lining gets swollen (40) .

    Gastritis may be caused by drinking excessive amounts of alcohol, eating spicy food , extreme stress, smoking, and long-term use of pain and fever medications.

    Bacterial infections , major surgeries, and traumatic injuries or burns may also cause gastritis.

        • Stomach upset or pain
        • Belching and hiccups
        • Bloating or gas
        • Bleeding of the belly or abdomen
        • Loss of appetite
        • Nausea and vomiting
        • Heartburn
        • Blood in the vomit or stool
        • Weight loss

        When untreated, gastritis may also result in other more severe health complications. These conditions include peptic ulcer disease (painful sores in the upper digestive tract) and tumors that could lead to stomach cancer .

        A study also found that gastritis was associated with an increased prevalence of panic attacks, social phobia, major depression, and mood disorders (42) .

        Conclusion

        Previously mentioned studies found that CBD might be useful in treating gastritis symptoms, such as inflammation, nausea, and pain.

        Compared with conventional medications prescribed for gastritis, CBD is generally safe because of its minimal side effects.

        Like honey, CBD was found to have antibacterial properties.

        CBD also comes in different forms and formulations, giving individuals with gastritis several options.

        While CBD has been deemed for its favorable safety profile, in some individuals, CBD oil may be hard on the stomach.

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        Can Cannabis Heal Stomach Ulcers? [Revealed]

        Nowadays, people use cannabis to address a whole range of medical conditions, including digestive issues like stomach ulcers.

        There are some obvious benefits to using marijuana for digestive problems. For example, we know that cannabinoids like THC and CBD can relieve nausea and pain symptoms. But can cannabis heal stomach ulcers, or is this just wishful thinking?

        Read on to find out.

        What Are Stomach Ulcers?

        Stomach ulcers (sometimes called peptic ulcers or gastric ulcers) occur when the stomach acid damages the lining of the digestive tract. When the mucus layer of the stomach is worn away and stops functioning effectively, the acid can damage the stomach tissue, causing the ulcer.

        Stomach ulcers are a common problem and can affect people of any age.

        Ulcers can occur in the esophagus or the duodenum, the upper part of the small intestine.

        Stomach ulcers are a common problem and can affect people of any age. However, they are more common in men and over the age of 60.

        Stomach Ulcer Symptoms

        The most common symptom of a stomach ulcer is abdominal pain. Patients describe the pain as burning or gnawing, and it usually occurs 2–3 hours after eating or at night. It usually starts in the central abdomen but can radiate to the chest, belly button, or back.

        Some other common stomach ulcer symptoms include:

        • Indigestion
        • Heartburn
        • Nausea
        • Loss of appetite
        • Weight loss

        In severe cases, a stomach ulcer can rupture and cause internal bleeding. Seek medical attention immediately if any of the following symptoms occur:

        • Bloody vomit (it may look bright red or brown)
        • Dark, sticky stools
        • Sudden, sharp pain that gets gradually worse over time

        What Causes Stomach Ulcers?

        People can develop stomach ulcers for several different reasons.

        One of the most common causes of stomach ulcers is a bacterium called Helicobacter pylori, or H. pylori for short.

        When these bacteria colonize the stomach, they cause inflammation (gastritis), which can eventually lead to ulceration. H. pylori are responsible for as many as 70–90% of gastric ulcers.

        Another common cause of stomach ulcers is the long-term use of non-steroidal anti-inflammatory drugs (NSAIDs). They include medications such as aspirin, ibuprofen, diclofenac, and naproxen.

        People frequently use NSAIDs to reduce inflammation in and around the body and relieve muscle and joint pain. However, over time, they can irritate the stomach lining and eventually cause ulcers. The risk of ulcers increases if the NSAIDs are taken in high doses or regularly for a long time.

        Some people believe that lifestyle factors such as diet and stress also contribute to stomach ulcers, although evidence is limited. However, things like spicy food, alcohol, and smoking irritate the stomach and could well aggravate pre-existing issues.

        Traditional Stomach Ulcer Treatments (Not Cannabis)

        Clinicians usually treat stomach ulcers with medications called proton pump inhibitors (PPIs). They include drugs like omeprazole and lansoprazole.

        PPIs work by reducing acid production in the stomach. If someone has an H. pylori infection, they will need a course of antibiotics in addition to PPIs.

        Some over-the-counter remedies like antacids may offer temporary relief from stomach ulcer symptoms. However, symptoms will keep returning until the underlying cause resolves.

        Does Cannabis Help Stomach Ulcers?

        In recent years, interest in medical marijuana for digestive issues has increased. Many studies suggest it could help with inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease.

        There is also some evidence that cannabis may help to protect the stomach from ulcers. It all surrounds something known as the endocannabinoid system (ECS). The ECS is a regulatory system present in most of the body’s tissues, including the digestive tract. It includes cell receptors, known as CB1 and CB2, and chemicals called endocannabinoids.

        A 2016 review for Current Neuropharmacology explains that there are high levels of these receptors and chemicals in the digestive system. They play a role in controlling inflammation and protecting the lining of the stomach and intestines from damage.

        The ECS is where the active compounds in cannabis exert their actions. For example, THC has a similar molecular shape to one of our natural endocannabinoids, anandamide. This allows it to bind with the same receptors, especially CB1.

        In recent years, interest in medical marijuana for digestive issues has increased.

        When it binds with CB1 receptors in the brain, THC produces the psychedelic high that has made cannabis so infamous. However, in the digestive system, it has very different effects.

        It reduces gastric acid production and slows the rate at which the stomach empties. Because of this decrease in gastric acid, cannabis, in theory, may help offer a sort of protection if an ulcer has formed.

        The authors of the 2016 review concluded: “the ECS can be a potential target to reduce the gastrointestinal mucosal lesions, hemorrhage, and inflammation.”

        Further research from the Journal of Clinical and Translational Science in 2019 supports these conclusions. It looked at a large number of clinical records from cannabis users and non-users. The study’s results suggested that cannabis users had a lower incidence of H. pylori, peptic ulcer disease, and related complications.

        Cannabis for Stomach Ulcer Symptom Relief

        In addition to potentially protecting the stomach lining from damage, cannabis could help with some specific stomach ulcer symptoms.

        Many patients use medical cannabis as a pain reliever. Humans have used the plant for this reason for millennia. Although the research into marijuana for pain provides somewhat mixed results, there is plenty of anecdotal evidence that it helps.

        As well as helping digestive pain, cannabis could provide a safer alternative to NSAIDs for people suffering from conditions like arthritis.

        Nausea

        Nausea is another common stomach ulcer symptom that cannabis may help. Research into cannabis and nausea suggests that both THC and CBD may have some benefits thanks to the way they interact with the ECS.

        Appetite

        Cannabis is well-known for producing a side effect known as ‘the munchies.’ Research indicates that this is due to the way that the ECS interacts with hunger hormones. Therefore, cannabis can both promote appetite and increase food intake for patients with stomach ulcers.

        Is CBD Oil Good for Stomach Ulcers?

        Although many states now have medical marijuana programs, the herb is not legal everywhere. An alternative that is far more widely available is CBD oil from industrial hemp. CBD is non-psychoactive, and experts consider it relatively safe and well-tolerated.

        Helping hundreds worldwide…

        While CBD does not interact directly with CB1 and CB2 receptors like THC does, it may still have some benefits for digestive health. It can increase the levels of our natural endocannabinoids by inhibiting the enzymes that break them down.

        There is currently no research specifically into CBD oil for stomach ulcers or CBD oil for ulcer pain. However, there is plenty of evidence to support its anti-inflammatory properties, and many people use it for everyday pain relief.

        How to Use Cannabis and CBD Oil for Stomach Ulcers

        The most typical way to use cannabis is by smoking it. However, smoking is one factor that may potentially aggravate stomach ulcers. Therefore, it may be better to choose an alternative consumption method.

        We were unable to find any evidence that one way of using cannabis for stomach ulcers is better than another. However, we can hypothesize that marijuana or CBD edibles may be particularly useful. They must pass through the digestive system once they are eaten, meaning that their cannabinoids reach the target area directly.

        Smoking may aggravate stomach ulcers. Therefore, it may be better to choose an alternative consumption method.

        If a person lives in a state where cannabis is legal, it is highly recommended that they purchased products from licensed dispensaries. By doing this, they reduce the risk of purchasing products that may have contaminants from illegitimate sources.

        Likewise, if a person opts for CBD products, they should be sure to buy from a reputable and trustworthy brand. There are a lot of companies selling low-quality products that contain little in the way of active cannabinoids. We recommend buying CBD online from a company that publishes third-party lab reports on its website. These reports ensure consumers are getting a product that is both effective and safe.

        You can read about some of our favorite tried and trusted brands here. Ultimately, it is important for every individual to conduct their own due diligence when researching these various products.

        Can Cannabis Heal Stomach Ulcers? Final Thoughts

        There is some evidence that cannabis could help stomach ulcers, although it may be more useful for prevention than cure. It appears to protect the digestive system through its influence on the body’s endocannabinoid system.

        It may also help with specific symptoms, including nausea, appetite, and pain. Thanks to their anti-inflammatory effects, cannabis and CBD could also help to reduce NSAID use for people concerned about ulcers.

        However, it is essential to exercise some caution and only buy cannabis or CBD products from reputable sources. Finally, if a person intends to use either cannabis or CBD oil for stomach ulcers, they should always consult a knowledgeable clinician first to ensure that it is safe and suitable to do so.

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