What is cbd oil tincture used for

CBD Oil: 9 Science-Backed Benefits

Dr. Bindiya Gandhi is an integrative medicine physician with expertise in functional and holistic medicine based in Atlanta, Georgia.

Commissions we earn from partner links on this page do not affect our opinions or evaluations. Our editorial content is based on thorough research and guidance from the Forbes Health Advisory Board.

Cannabidiol, or CBD, is a chemical compound found in the cannabis sativa plant. When applied topically or consumed through smoke inhalation or edible consumption, CBD interacts with neuroreceptors in your endocannabinoid system, which sends signals between your cells to help regulate your movement, mood, homeostasis and immune system.

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CBD is often extracted from the cannabis sativa plant in oil form and mixed with an inert carrier oil like hemp seed oil for consumption. In fact, of the 60% of U.S. adults who report having used CBD before, 55% of them use CBD oils and tinctures specifically, according to a recent Forbes Health survey of 2,000 U.S. adults conducted by OnePoll.

CBD research is growing, too. Here are nine ways studies suggest CBD oil could benefit your health.

1. Offset Anxiety and Depression

CBD’s ability to calm is perhaps its most popular effect and the reason its use is so widespread. A 2017 study in the Brazilian Journal of Psychiatry tested the anxiety levels of 57 men in a simulated public speaking test. Some received a placebo while others received either 150 milligrams, 300 milligrams or 600 milligrams of CBD before their speeches. Those who received 300 milligrams of CBD experienced significantly reduced anxiety during the test compared to those who received the placebo. Interestingly, participants who received either 150 or 600 milligrams of CBD experienced more anxiety during the test than the 300 milligrams group.

Meanwhile, at least one study in mice revealed CBD had effects similar to the antidepressant imipramine. Human trials are needed, though, to confirm whether CBD can induce this same antidepressant reaction in our bodies.

2. Treat Select Epilepsy Syndromes

In some instances, CBD can be used to treat epileptic seizures.

In 2018, the Food and Drug Administration (FDA) approved the use of CBD under the brand name Epidiolex to treat seizures resulting from Lennox-Gastaut syndrome and Dravet syndrome—two rare forms of epilepsy—in patients at least 2 years old.

Three well-vetted studies provide the basis of support for the FDA’s decision. In these trials, 516 patients with Lennox-Gastaut syndrome or Dravet syndrome received either Epidiolex or a placebo. Epidiolex, when taken along with other prescribed medications, decreased the frequency of participants’ seizures compared to the placebo.

3. Reduce PTSD Symptoms

In a small 2018 study in the Journal of Alternative and Complementary Medicine, 11 people with post-traumatic stress disorder (PTSD) received CBD along with routine psychiatric care for eight weeks in an outpatient psychiatric clinic. Ten of the 11 experienced a decrease in their PTSD symptoms. CBD was generally well tolerated, the researchers write.

Margaret Rajnic, a doctor of nursing practice experienced in medical cannabis and CBD, emphasizes the importance of using therapy in tandem with any type of cannabis or CBD for PTSD. “There is an amount of therapy that is needed for PTSD,” she says. “But CBD will give you that little bit of decreased anxiety.”

Four other human trials from 2012 to 2016 suggest CBD reduces PTSD symptoms, although some include THC, or tetrahydrocannabinol, the main mind-altering element in cannabis. When THC and CBD work together, they create what’s called an “entourage effect,” complementing each other’s benefits and potency. For example, taking the same dose of THC and CBD together tempers the “high” from THC, while just a little THC paired with more CBD enhances the effects of the CBD.

4. Treat Opioid Addiction

Some studies—both preclinical animal and human clinical trials—suggest CBD could be used to help treat people who are dependent on opioids.

In one such study, researchers administered CBD to people with heroin use disorder. Over the course of a week, CBD significantly reduced heroin users’ cue-induced cravings, withdrawal anxiety, resting heart rate and salivary cortisol levels. No serious adverse effects were found.

Other studies find CBD helpful in reducing various psychiatric and medical symptoms like anxiety, insomnia and pain in patients with substance use disorders, indicating that CBD may be an effective treatment for opioid addiction. However, further studies are necessary.

5. Alleviate ALS Symptoms

Amyotrophic lateral sclerosis (ALS) is a disease that causes nerve cells in the brain and spinal cord to deteriorate, resulting in loss of muscle control that worsens over time. It’s not yet understood exactly why ALS occurs, although it can be hereditary in some cases. There’s no known cure, and there are only two FDA-approved medications to help treat ALS symptoms.

Research suggests people with ALS can benefit from the entourage effect created by the combination of THC and CBD, similar to people with PTSD. In a 2019 study, patients received a combination of THC and CBD in varying doses depending on their needs and preferences. Those with mild, moderate or severe spasticity (muscle tightness and stiffness) due to ALS reported high levels of satisfaction with the treatment, and those with moderate to severe spasticity reported higher satisfaction rates than those with mild spasticity.

6. Relieve Unmanageable Pain

In 2005, Canada approved the use of Sativex, an oromucosal (absorbed in the lining of the mouth) spray with equal proportions of THC and CBD, for the treatment of multiple sclerosis-related central neuropathic pain. In 2007, Canada approved the medicine’s use again for cancer pain that proved unresponsive to other medications.

Meanwhile, continued studies in the U.S. indicate CBD is effective in treating chronic, non-cancer pain. In one 2020 study, researchers administered CBD topically to a group of patients with symptomatic peripheral neuropathy (a result of brain nerve and spinal cord nerve damage) while another group with the same condition received a placebo. Results showed a significant reduction in intense, sharp pains and cold, itchy sensations in those who used the topical CBD compared to those who used the placebo. No participants reported adverse side effects.

When introduced topically, CBD oil doesn’t affect the systemic issue as it might if it were introduced directly into the bloodstream. Instead, topical CBD is more localized and treats pain in a certain area. Since it’s more direct, it may have a more pronounced effect.

7. Ease Diabetic Complications

For starters, tests on human cells found that CBD helps reduce the effects of high glucose levels on other cells in the body, which typically precedes the development of diabetes and various complications. Researchers concluded that with further studies, CBD could have significant benefits when used in patients with diabetes, diabetic complications and plaque buildup in artery walls.

In another small study, 13 patients with type 2 diabetes who weren’t on insulin treatment were given both CBD and a placebo (in lieu of insulin). Researchers found CBD decreased their levels of resistin (which causes resistance to insulin, the protein that regulates sugar levels) and increased their levels of glucose-dependent insulinotropic peptide (a hormone that ensures a sufficient release of insulin from digested food) compared to their baselines before they started the test. These results suggest CBD could be a natural treatment for diabetes by helping the body regulate insulin-related hormone levels.

8. Protect Against Neurological Disease

Preclinical and clinical studies show that CBD has antioxidant and anti-inflammatory properties. Researchers deduce these characteristics can provide significant neuroprotection, or protection against numerous pathological disorders.

Several preclinical studies suggest CBD can produce beneficial effects against Parkinson’s disease, Alzheimer’s disease and multiple sclerosis. Huntington’s disease and cerebral ischemia were also tested, although significant positive results were not recorded. Further clinical studies are needed to confirm CBD’s benefits when used as a treatment for these disorders.

9. Inhibit Arthritis Symptoms

Arthritis involves the deterioration of the tissues in and around your joints. There are several types of arthritis, and symptoms include pain, stiffness and loss of motion. Arthritis treatment usually targets pain relief and improved joint function.

A 2006 study found that Sativex—a CBD-based botanical drug approved in the United Kingdom in 2010—promoted statistically significant improvements in quality of sleep, pain during movement and pain at rest in patients with rheumatoid arthritis when compared to a placebo. It was the first controlled trial of Sativex as a treatment for rheumatoid arthritis, involving 58 patients. CBD was found to have a pain-relieving effect, as well as an ability to suppress disease activity.

In 2018, in a study of more localized treatment, researchers administered a synthetic CBD gel in either 250-milligram or 500-milligram doses daily or a placebo to patients with knee pain due to osteoarthritis. Patients also stopped taking any other anti-inflammatory medications or painkillers, with the exception of acetaminophen, before and during the study period.

The results were interesting, although not entirely conclusive. On one hand, those treated with CBD did not experience much change in pain when compared with placebo patients. On the other hand, there were statistically significant differences between the group receiving the 250-milligram dose and the placebo group when measuring the average weekly improvement of their worst pain levels and their WOMAC (Western Ontario and McMaster Universities Arthritis Index) physical function rating. Additionally, men seemed to benefit from CBD more significantly than women in this test.

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All you need to know about CBD Tincture

Cannabis has three natural varieties namely Sativa, Indica, and Regulars. Cannabis Sativa, popularly called hemp has about 500 naturally occurring chemicals.

This long list contains quite a lot of cannabinoids, phytonutrients, terpenes, flavonoids, and quite a lot more.

The long list of cannabinoids feature names like Cannabidiol (CBD), Cannabichromene (CBC), Cannabinol (CBN), Cannabigerol (CBG), and Tetrahydrocannabinol (THC).

Hemp contains more than a hundred cannabinoids, and each of them has its unique benefits. As an example, CBD is well-renowned for its medicinal, health, and wellness benefits while THC is popular for its recreational high use and has euphoric, psychoactive, or mind-altering effects.

When we talk about cannabinoids usually we talk about CBD and THC, however, the entire lot has its uses. They bind themselves to the endocannabinoid receptors in our body’s Endocannabinoid System (ECS) and the Central Nervous System (CNS). These reduce pain, inflammation, and mental functions in general. In this article, we will understand CBD and more particularly CBD Tincture.

What is CBD?

Cannabidiol or CBD is one of the most researched cannabinoids and widely used for its medicinal and wellness utilities as classified by the US National Library of Medicine. It is used in a variety of products of edible, inhalant (smoke or vapour), and topical variety.

It is extracted from Cannabis Sativa and since its rediscovery in 1940 by Roger Adams, a chemist trained at Harvard we have a detailed chemical structure of CBD. By 2019, clinical research indicated positive results on people suffering from stress/anxiety, neurological problems, movement disorders, cognition, pain, and inflammation.

The plants become productive with the best benefits and most active natural chemicals between 108 and 120 days. CBD binds with the ECS and provides relief by actively communicating with it.

ECS is probably the most important physiological system involved in establishing and maintaining health. It has a pivotal role to play in the regulation of processes and functions like sleep, appetite, mood, reproduction, memory, and fertility.

CBD is extracted in three main formats or compositions.

This variant contains all of the cannabinoids, nutrients, terpenes, and flavonoids. By definition, this also contains THC along with CBD and other cannabinoids. As per the regulations of the FDA at most this can contain 0.3% of THC. This is to make sure the benefits can be used and at the same time abuse can be controlled as this small amount of THC can’t be used for the high it usually delivers.

This has all the natural compounds from Hemp or Cannabis Sativa except THC. This has the benefits from all of the cannabinoids and the other natural chemicals but has no trace for THC because of obvious reasons. Many people are not well receptive to THC. This is mostly used for edible CBD-based products.

Only Cannabidiol or CBD is further extracted or isolated from all the extracted terpenes, flavonoids, and cannabinoids. This contains the highest concentration of CBD and is very potent when it comes to it. This variant of CBD is used in topical ointments, balms, creams, and other skincare products.

What Is CBD Tincture?

Medications with an alcohol base are classified as Tincture. They are made for edible usage and administered in some drops. CBD is extracted from hemp and infused with distilled alcohol concentrated at 60-70%. In some cases, glycerine is also used.

The presence of alcohol as a carrier gives it a long shelf life and easy absorption through the mouth and intestines. The tincture is predominantly for medicinal use and is bitter owing to its alcohol base.

How to use CBD Tincture?

CBD Tincture is administered in drops, sublingually. Once you drop about 2-3 drops under the tongue, CBD gets absorbed through the sublingual artery, travels to the carotid artery, and through the heart to the bloodstream and entire body.

After holding the tincture in your mouth for about 45 seconds to a minute and absorption through the sublingual artery the rest can be swallowed with saliva. In this way, it reaches the intestines and gets absorbed by the intestinal walls to reach the bloodstream.

CBD reaches the different parts of the body and reacts with the ECS and CNS for benefits to our physical and mental health. They come in small glass bottles with a marked dropper in the cap for easy dosage.

How is CBD Tincture made?

Hemp flowers and leaves are immersed in alcohol concentrated at about 60-70%. In some cases, glycerine is also used. This is the basic process of creating a CBD Tincture. Due to the bitter taste of CBD Tincture and for additional benefits some other nutrients and natural compounds are added.

Some of them include.

  • Water
  • Melatonin
  • Herbs
  • Vitamins B12, D, C, etc.
  • Sweeteners
  • Oils like lavender, basil, etc.

These additional ingredients vary from manufacturer to manufacturer and their resultant products. As an example, OleyHemp produced CBD Tincture contains full-spectrum CBD, is alcohol-based, and only additional cherry or orange flavour is added for the deliciousness aspect to reduce its bitterness.

Benefits of CBD Tincture

There are many benefits of orally ingested CBD, specifically CBD Tincture and most of these are medicinal and for health benefits.

CBD is very effective in reducing seizure-type conditions and is used for the treatment of epilepsy. Epidiolex, a drug manufactured by GW Pharmaceuticals has shown proven results in children and adults alike for seizure issues. Epidiolex is a recognized prescription drug for the treatment of seizures from Dravet syndrome, Tuberous Sclerosis, and Lennon Gastaut syndrome.

It is also well-known to reduce seizures from febrile infection-related epilepsy syndrome (FIRES), Sturge-Weber syndrome, and other genetical disorders that may cause epileptic encephalopathy.

Multiple Sclerosis (MS) is chronic and severely affects the CNS (brain, spinal cord, and optic nerves). Full-spectrum CBD can be effective for improving tight or frozen muscles, related pain, and frequency in urination for patients suffering from Sclerosis.

MS causes numbness and tingling limbs, and also blurred vision. In more severe cases, it is also known to cause vision loss, mobility problems, and even paralysis. Though MS has no prescribed fully curable treatment, CBD can reduce the progression of the disease and reduce the resulting pain.

CBD has been very effective in addiction control especially for regular marijuana users. Using CBD Tincture can reduce the THC intake or overall dependency on it. This considerably reduces the use of cannabis and even more so for the people who are looking to quit marijuana or cannabis.

Going through withdrawal is also an important factor when it comes to quitting the regular use of addictive substances like morphine, heroin, or other opioid-based drugs. Using CBD for 3-7 days can reduce anxiety and cravings to a considerable extent.

This involuntary muscle contraction condition can be controlled to a huge extent by CBD’s reactions with the CNS and ECS. As CBD Tincture is edible it reaches the entire body through the bloodstream and has positive effects and improves muscle and motor control.

CBD Tincture is also somewhat effective by relaxing the nervous system and nerve signals and thus control, uncontrollable shaking and tremors in the body.

The pain of chronic, acute, or neurological type can be countered with CBD Tincture. Pain is a result of heavy impact or bruises and inflammation.

Also, muscle damage is caused by strenuous exercise or workouts. Sore muscles and heavy exercise causes muscle fatigue and damage to the fibres. CBD is known to relieve pain and inflammation caused by strain on muscles and heavy exercise.

Learning disabilities conditions that are inherited can be controlled by using CBD Tincture. It effectively reduces anxiety and improves children’s behaviour with a fragile x syndrome condition.

In this case, a body graft or transplant attacks the host body. Graft-versus-host disease (GVHD) mostly occurs after a bone marrow transplant. Using CBD Tincture for 7 days before the graft and continuing for 30 days after the graft can reduce the chances of encountering GVHD.

Early research and studies indicate that using CBD improves the conditions and enhances well-being in people suffering from schizophrenia.

Stress and anxiety is a big factor in many well-being problems. Too much stress can cause depression and many other conditions like insomnia and even impact overall wellness. Too much anxiety can cause problems in speaking and expressing control. CBD can reduce social anxiety disorder and also stress caused by most situations.

Regularly using CBD Tincture reduces psychotic symptoms and anxiety in people suffering from Parkinson’s disease.

In addition to the above, CBD Tincture can help with a lot of other issues like nerve damage, Bipolar disorder, and a lot of other physical, mental and neurological conditions, but they need further detailed research.

The 2018 Farm Bill has legalized hemp and its products in the USA. But necessarily that does not mean all help derived products are legal.

The FDA regulations clearly state that 0.3% of THC is allowed in hemp products. Many organic manufacturers do not clearly state the amount of THC and other cannabinoids present in their products.

Expectant or breastfeeding mothers, people suffering from liver problems, and children should stay away from CBD Tincture till they speak to a medical practitioner as we do not know the full extent of its side effects yet due to limited research. However, it has been observed that CBD does not have any harmful side effects.

CBD Tincture is one of the many ways to consume CBD and reap its benefits. They have an unusually long shelf life, are easy to carry and administer, and measurably dose. As there are many organic manufacturers available you need to choose wisely and choose one that best fits your need.

As an example, OleyHemp produces all its hemp at its farms spread out to more than one state and uses no pesticides or harmful chemicals in the production process. The product manufacturing also is done at its state-of-the-art processing facilities with full emphasis on the output quality.

To gain the most benefits use CBD Tincture from organic product manufacturers with repute and true labels. Visit their sites and see the QC test reports to make sure of what you see is what you