Who to contact for reliability regarding a cbd oil product

Reliable CBD Product Testing: Regulation, Usage and Testing of Cannabis and Cannabinoids

Any discussion of cannabinoids must begin by defining the various terms which will be included in that discussion. Cannabis is a genus of flowering plants that are generally agreed to be comprised of three species: Cannabis sativa, Cannabis indica and Cannabis ruderalis.

Cannabinoids are naturally occurring constituents of the Cannabis plant which can be isolated for specific commercial and medicinal uses. Two of the most commonly discussed cannabinoids are 9-THC (Δ-9-tetrahydrocannabinol) and CBD (Cannabidiol).

Historically, the Cannabis genus of plants have been referred to by many names including “marijuana” and “hemp” but here in the US and especially since 2018, Industrial Hemp has been specifically defined (for regulatory purposes) as Cannabis sativa having a 9-THC content less than 0.3% (on the dried basis) which is sourced from a grower of Industrial Hemp licensed under the Agriculture Improvement Act of 2018 (better known as the 2018 Farm Bill, PL 115-334).

Federal Regulation of Cannabis and Cannabinoids

Prior to 2018, the US Department of Justice categorized all species of Cannabis and cannabinoids derived from them as Schedule I Controlled Substances, meaning they were categorized as being illegal substances having a high potential for abuse and no legitimate medical usage.

The 2018 Farm Bill removed Industrial Hemp (as defined above) from the Schedule I category of Controlled Substances, thereby opening the door for its usage in commercial applications. The Farm Bill however preserved the FDA’s authority over hemp products that fall under its jurisdiction.

Thus products that incorporate Industrial Hemp or cannabinoids derived from Industrial Hemp into their composition must meet any applicable FDA requirements and standards, just like any other FDA-regulated product.

Since the FDA has already approved a New Drug Application for a CBD drug product (Epidiolex) and has already approved several Investigational New Drug Applications for 9-THC, Section 201(ff)(3)(B) of the Food Drug and Cosmetic Act specifically forbids the usage of either CBD or 9-THC as dietary supplements or ingredients for human food or animal food.

Additionally, CBD and 9-THC may not be added to OTC drug products as active ingredients unless first approved by the FDA through a New Drug Application.

Except for CBD and 9-THC, the FDA does not currently restrict the use of any other cannabinoids derived from Industrial Hemp for use in human food or dietary supplements.

It should be noted that in December of 2018, the FDA granted GRAS (Generally Regarded As Safe) status to three hemp-seed derived ingredients for use in human food: hulled hemp seed, hemp seed protein powder, and hemp seed oil.

This decision was based upon the fact that the seeds of the hemp plant do not contain CBD or 9-THC.

State Regulation of Cannabis and Cannabinoids

At the State level, there is tremendous variation in the regulation of Cannabis and cannabinoids.

Some states have legalized all species of Cannabis and the cannabinoids derived from them for use as a medicine, recreational drug, food ingredient or dietary supplement.

Other states simply observe Federal law while others have adopted intermediate positions between total legalization and what Federal law currently allows regarding the use of Industrial Hemp.

This contradicting patchwork of Federal law and State regulations has given rise to many complications affecting members of the marijuana industry.

For example, some banks have adopted policies of not providing loans to industry members participating in activities beyond what Federal law currently allows, even if they are located within a state which has ‘legalized’ all Cannabis species; Some courts refuse to hear cases brought by industry members in attempts to recoup money owed them by vendors or client organizations since they are viewed as participating in “illegal” activities which violate Federal law.

Clearly, until there is a harmonization of Federal and State laws, this legal turmoil will continue to plague the marijuana industry.

Commercial Usage of Cannabis and Cannabinoids

Although Cannabis contains many cannabinoids, terpene compounds and other naturally occurring components of biological interest, 9-THC and CBD have thus far received the most interest for commercial applications.

In States where all species of Cannabis have been legalized, a wide range of products is offered which contain 9-THC and/or CBD including recreational drug “candies” (e.g., gummy bears), food or beverage items and even some dietary supplements – all in direct violation of Federal law and the Food, Drug and Cosmetic Act.

Of a far less controversial nature, many cosmetic and personal care products now include CBD derived from Industrial Hemp as a featured ingredient.

Dietary supplements free of CBD and 9-THC but containing other cannabinoids and components derived from Industrial Hemp (e.g., hemp seed oil) are legal in all jurisdictions and are also growing in popularity.

So What Can We Conclude From All of This?

  1. 9-THC and CBD are only two of the many cannabinoids naturally occurring in all species of the Cannabis plant.
  2. For regulatory purposes, Industrial Hemp is defined as the Cannabis species Cannabis sativa having a 9-THC content less than 0.3% (on the dried basis) which is sourced from a grower of Industrial Hemp licensed under the Agriculture Improvement Act of 2018 (better known as the 2018 Farm Bill, PL 115-334).
  3. Federal law allows the use of Industrial Hemp and constituents derived from it in a wide range of products, however, some uses are restricted by FDA.
  4. The Food, Drug and Cosmetic Actstrictly forbidsthe use of9-THC and/or CBD as dietary supplements and ingredients in human food, animal food and OTC Drugs. (Dietary supplements, human food, animal food and OTC Drugs may contain Industrial Hemp or components derived from Industrial Hemp so long as 9-THC and CBD have been excluded.)
  5. Cosmetic and Personal Care products may legally contain Industrial Hemp and its derivatives including CBDat any level and 9-THC below 0.3%.
  6. Contradictions between Federal and State laws have given rise to significant legal and business issues which currently plague the marijuana industry beyond the usage of Industrial Hemp in regulated products.

Let CPT℠ assist with your CBD Product Testing from your Cannabis-derived raw materials to the final Cannabinoid-containing products.

CPT℠ is an ISO/IEC 17025 accredited laboratory for conducting Cannabinoid Content Testing in raw materials and finished products. We can assist in determining the quality and legality of your raw materials and finished products regardless of their form.

Cosmetic/personal care products, foods, dietary supplements and beverages all fall within our area of expertise when testing for specific cannabinoids such as 9-THC and CBD or compiling a complete cannabinoid profile. Why not contact us today?

What You Need to Know (And What We’re Working to Find Out) About Products Containing Cannabis or Cannabis-derived Compounds, Including CBD

The FDA is working to answer questions about the science, safety, and quality of products containing cannabis and cannabis-derived compounds, particularly CBD.

  • Cannabis is a plant of the Cannabaceae family and contains more than eighty biologically active chemical compounds. The most commonly known compounds are delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). THC is the component that produces the “high” associated with marijuana use. Much interest has been seen around CBD and its potential related to health benefits.
  • Marijuana is different from CBD. CBD is a single compound in the cannabis plant, and marijuana is a type of cannabis plant or plant material that contains many naturally occurring compounds, including CBD and THC.
  • The FDA has approved only one CBD product, a prescription drug product to treat seizures associated with Lennox Gastaut syndrome (LGS), Dravet syndrome (DS), or tuberous sclerosis complex (TSC) in people one year of age and older.
  • It is currently illegal to market CBD by adding it to a food or labeling it as a dietary supplement.
  • The FDA has seen only limited data about CBD safety and these data point to real risks that need to be considered before taking CBD for any reason.
  • Some CBD products are being marketed with unproven medical claims and are of unknown quality.
  • The FDA will continue to update the public as it learns more about CBD.

Potential harm, side effects and unknowns

  1. CBD has the potential to harm you, and harm can happen even before you become aware of it.
    • CBD can cause liver injury.
    • CBD can affect how other drugs you are taking work, potentially causing serious side effects.
    • Use of CBD with alcohol or other drugs that slow brain activity, such as those used to treat anxiety, panic, stress, or sleep disorders, increases the risk of sedation and drowsiness, which can lead to injuries.
    • Male reproductive toxicity, or damage to fertility in males or male offspring of women who have been exposed, has been reported in studies of animals exposed to CBD.
  2. CBD can cause side effects that you might notice. These side effects should improve when CBD is stopped or when the amount used is reduced.
    • Changes in alertness, most commonly experienced as somnolence (drowsiness or sleepiness).
    • Gastrointestinal distress, most commonly experienced as diarrhea and/or decreased appetite.
    • Changes in mood, most commonly experienced as irritability and agitation.
  3. There are many important aspects about CBD that we just don’t know, such as:
    • What happens if you take CBD daily for sustained periods of time?
    • What level of intake triggers the known risks associated with CBD?
    • How do different methods of consumption affect intake (e.g., oral consumption, topical , smoking or vaping)?
    • What is the effect of CBD on the developing brain (such as on children who take CBD)?
    • What are the effects of CBD on the developing fetus or breastfed newborn?
    • How does CBD interact with herbs and other plant materials?
    • Does CBD cause male reproductive toxicity in humans, as has been reported in studies of animals?

Unanswered questions about the science, safety, and quality

You may have noticed that cannabidiol (CBD) seems to be available almost everywhere, and marketed as a variety of products including drugs, food, dietary supplements, cosmetics, and animal health products. Other than one prescription drug product to treat seizures associated with Lennox Gastaut syndrome (LGS), Dravet syndrome (DS), or tuberous sclerosis complex (TSC) in people one year of age and older, the U.S. Food and Drug Administration (FDA) has not approved any other CBD products, and there is very limited available information about CBD, including about its effects on the body.

The FDA recognizes the significant public interest in cannabis and cannabis-derived compounds, particularly CBD. However, there are many unanswered questions about the science, safety, and quality of products containing CBD. The agency is working on answering these questions through ongoing efforts including feedback from a recent FDA hearing and information and data gathering through a public docket.

Despite the 2018 Farm Bill removing hemp — defined as cannabis and cannabis derivatives with very low concentrations (no more than 0.3% on a dry weight basis) of THC — from the definition of marijuana in the Controlled Substances Act, CBD products are still subject to the same laws and requirements as FDA-regulated products that contain any other substance.

The FDA is concerned that people may mistakenly believe that using CBD “can’t hurt.” The agency wants to be clear that we have seen only limited data about CBD’s safety and these data point to real risks that need to be considered. As part of the drug review and approval process for the prescription drug containing CBD, it was determined that the risks are outweighed by the benefits of the approved drug for the particular population for which it was intended. Consumer use of any CBD products should always be discussed with a healthcare provider. Consumers should be aware of the potential risks associated with using CBD products. Some of these can occur without your awareness, such as:

  • Liver Injury: During its review of the marketing application for Epidiolex — a purified form of CBD that the FDA approved in 2018 for use in the treatment of two rare and severe seizure disorders — the FDA identified certain safety risks, including the potential for liver injury. This serious risk can be managed when an FDA-approved CBD drug product is taken under medical supervision, but it is less clear how it might be managed when CBD is used far more widely, without medical supervision, and not in accordance with FDA-approved labeling. Although this risk was increased when taken with other drugs that impact the liver, signs of liver injury were seen also in patients not on those drugs. The occurrence of this liver injury was identified through blood tests, as is often the case with early problems with the liver. Liver injury was also seen in other studies of CBD in published literature. We are concerned about potential liver injury associated with CBD use that could go undetected if not monitored by a healthcare provider.
  • Drug Interactions: Information from studies of the FDA-approved CBD drug Epidiolex show that there is a risk of CBD impacting other medicines you take – or that other medicines you take could impact the dose of CBD that can safely be used. Taking CBD with other medications may increase or decrease the effects of the other medications. This may lead to an increased chance of adverse effects from, or decreased effectiveness of, the other medications. Drug interactions were also seen in other studies of CBD in published literature. We are concerned about the potential safety of taking other medicines with CBD when not being monitored by a healthcare provider. In addition, there is limited research on the interactions between CBD products and herbs or other plant-based products in dietary supplements. Consumers should use caution when combining CBD products with herbs or dietary supplements.
  • Male Reproductive Toxicity: Studies in laboratory animals showed male reproductive toxicity, including in the male offspring of CBD-treated pregnant females. The changes seen include decrease in testicular size, inhibition of sperm growth and development, and decreased circulating testosterone, among others. Because these findings were only seen in animals, it is not yet clear what these findings mean for human patients and the impact it could have on men (or the male children of pregnant women) who take CBD. For instance, these findings raise the concern that CBD could negatively affect a man’s fertility. Further testing and evaluation are needed to better understand this potential risk.

In addition, CBD can be the cause of side effects that you might notice. These side effects should improve when CBD is stopped or when the amount used is reduced. This could include changes in alertness, most commonly experienced as somnolence (sleepiness), but this could also include insomnia; gastrointestinal distress, most commonly experienced as diarrhea and/or decreased appetite but could also include abdominal pain or upset stomach; and changes in mood, most commonly experienced as irritability and agitation.

The FDA is actively working to learn more about the safety of CBD and CBD products, including the risks identified above and other topics, such as:

  • Cumulative Exposure: The cumulative exposure to CBD if people access it across a broad range of consumer products. For example, what happens if you eat food with CBD in it, use CBD-infused skin cream and take other CBD-based products on the same day? How much CBD is absorbed from your skin cream? What if you use these products daily for a week or a month?
  • Special Populations: The effects of CBD on other special populations (e.g., the elderly, children, adolescents, pregnant and lactating women).
  • CBD and Animals: The safety of CBD use in pets and other animals, including considerations of species, breed, or class and the safety of the resulting human food products (e.g., meat milk, or eggs) from food-producing species.

Unproven medical claims, unsafe manufacturing practices

Some CBD Products are Being Marketed with Unproven Medical Claims and Could be Produced with Unsafe Manufacturing Practices

Unlike the FDA-approved CBD drug product, unapproved CBD products, which could include cosmetics, foods, products marketed as dietary supplements, and any other product (other than Epidiolex) making therapeutic claims, have not been subject to FDA evaluation regarding whether they are effective to treat a particular disease or have other effects that may be claimed. In addition, they have not been evaluated by the FDA to determine what the proper dosage is, how they could interact with other drugs or foods, or whether they have dangerous side effects or other safety concerns.

Misleading, unproven, or false claims associated with CBD products may lead consumers to put off getting important medical care, such as proper diagnosis, treatment, and supportive care. For that reason, it’s important to talk to your doctor about the best way to treat diseases or conditions with available FDA-approved treatment options.

In addition to safety risks and unproven claims, the quality of many CBD products may also be in question. The FDA is also concerned that a lack of appropriate processing controls and practices can put consumers at additional risks. For example, the agency has tested the chemical content of cannabinoid compounds in some of the products, and many were found to not contain the levels of CBD they claimed. We are also investigating reports of CBD potentially containing unsafe levels of contaminants (e.g., pesticides, heavy metals, THC).

CBD products are also being marketed for pets and other animals. The FDA has not approved CBD for any use in animals and the concerns regarding CBD products with unproven medical claims and of unknown quality equally apply to CBD products marketed for animals. The FDA recommends pet owners talk with their veterinarians about appropriate treatment options for their pets.

The FDA’s top priority is to protect the public health. This priority includes making sure consumers know about products that put their health and safety at greatest risk, such as those claiming to prevent, diagnose, treat, mitigate, or cure serious diseases. For example, the agency has warned companies to stop selling CBD products they claim are intended to prevent, diagnose, treat, mitigate, or cure serious diseases such as cancer, Alzheimer’s disease, psychiatric disorders and diabetes. While we have focused on these types of products, we will continue to monitor the marketplace for any product that poses a risk to public health, including those with dangerous contaminants, those marketed to vulnerable populations, and products that otherwise put the public health at risk.

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Evaluation of the regulatory frameworks

The FDA is Continuing to Evaluate the Regulatory Frameworks for Products Containing Cannabis and Cannabis-Derived Compounds

The FDA continues to believe the drug approval process represents the best way to ensure that safe and effective new medicines, including any drugs derived from cannabis, are available to patients in need of appropriate medical therapy. The agency is committed to supporting the development of new drugs, including cannabis and cannabis-derived drugs, through the investigational new drug and drug approval process.

We are aware that there may be some products on the market that add CBD to a food or label CBD as a dietary supplement. Under federal law, it is illegal to market CBD this way.

The FDA is evaluating the regulatory frameworks that apply to certain cannabis-derived products that are intended for non-drug uses, including whether and/or how the FDA might consider updating its regulations, as well as whether potential legislation might be appropriate. The information we have underscores the need for further study and high quality, scientific information about the safety and potential uses of CBD.

The FDA is committed to setting sound, science-based policy. The FDA is raising these safety, marketing, and labeling concerns because we want you to know what we know. We encourage consumers to think carefully before exposing themselves, their family, or their pets, to any product, especially products like CBD, which may have potential risks, be of unknown quality, and have unproven benefits.

Our Consumer Update includes a practical summary of what we know to date. As we learn more, our goal is to update you with the information you need to make informed choices about CBD products. Also, as the regulatory pathways are clarified we will take care to inform all stakeholders as quickly as possible.

10 Best CBD Companies to Buy From in 2022: Honest Reviews & Guide

Once an obscure niche product, CBD is now undoubtedly mainstream. Due to a continuing lack of FDA regulation, however, there are no overarching quality standards in the CBD industry.

Consequently, consumers have to determine which CBD products are high-quality and effective. To make it easier for you to choose CBD oil brands that offer the best value and the safest products, we put together this detailed review of the best CBD brands of 2022 and beyond.

Best CBD Companies Ranked

Other Great Brands

  1. CBDistillery
  2. Charlotte’s Web
  3. Lazarus Naturals
  4. Royal CBD
  5. JustCBD

Which Company Has The Best CBD Oil in 2022?

To find the best CBD oil companies on the market, we devised a set of criteria that we applied to each brand that we considered. Leveraging our own expertise and calling upon the insight of industry experts, we determined the value that each brand in our list provides by thoroughly evaluating the following factors:

1. Brand Credibility

  • How adaptive and well-designed was the brand’s website?
  • How well was their site content written?
  • How quickly did they respond to customer inquiries?

These are just a few examples of the variables we used to determine brand credibility.

2. Hemp Source

U.S. hemp is the highest-quality, and using hemp grown in the United States supports the domestic agricultural economy. Brands that used organically grown hemp cultivated in the United States received the highest grades.

We also took into account factors such as whether a brand’s hemp was U.S. hemp authority-certified or non-GMO. At this point, non-GMO hemp is the standard in the industry, so we disqualified brands that used hemp that was genetically modified.

3. Extraction & Purification

There are a variety of solvents that brands can use to extract CBD from hemp. Some of these solvents are difficult to purge from finished products, however, and they can cause respiratory harm.

Carbon dioxide is widely recognized as the safest extraction solvent for hemp. As a result, brands that use CO2 extraction received high scores, while brands that use butane, ethanol, or acetone extraction were penalized.

4. Lab Reports

In lieu of FDA regulation, third-party lab testing has become the gold standard for determining a hemp product’s safety and quality. CBD products that have been third-party lab tested can be verified as not containing contaminants.

However, there are quite a few different third-party lab test providers on the market, and some are less independent than they seem. In addition to making sure that products were tested, we also looked at which company provided the lab tests for each of the hemp brands we examined.

5. Customer Service

You can learn a lot from how a CBD brand handles its customer service. Obviously, customers are better served by brands that respond quickly and offer courteous customer service.

If a CBD brand’s customer service is lackluster, however, that brand might also be lacking in other ways. We checked each brand’s customer service capabilities to determine its overall integrity and attention to detail.

How Our Experts Chose These Criteria

We’re no strangers to the CBD industry. We’ve watched interest in CBD grow over the years, and we’ve observed the highest and lowest points in the industry’s history.

Over time, the experts who put together this guide have had plenty of chances to compare and contrast CBD companies. We’ve seen which companies have risen to the top, and we’ve seen how they achieved these results.

At the same time, we’ve become familiar with the most common points of failure within the CBD industry. We developed our evaluation criteria based on longitudinal research into the brand factors that are most likely to result in high-quality CBD products.

Best CBD Companies: Detailed Reviews

Colorado Botanicals: Best All-Around & Highest Quality

After extensively considering each brand’s benefits and drawbacks, we determined that Colorado Botanicals offers the best products for the most reasonable prices. This brand offers similar product types to major competitors, but it enhances these products’ benefits by tapping into the hemp plant’s true potential.

Brand Credibility

Colorado Botanicals isn’t a household name, but the company more than holds up against its bigger competitors. Every aspect of the Colorado Botanicals brand met our strict criteria for excellence.

  • Clean, simple website with excellent graphics
  • Detailed product information and site content
  • Highly detailed third-party testing reports
  • Broad-spectrum, THC-free CBD products
  • Extensive focus on the benefits of terpenes

Colorado Botanicals also won our top spot for Best CBD Oil and Best CBG Oil of 2022, proving that quality – not famous branding – determines a product’s success.

Extraction & Purification Standards

Colorado Botanicals uses CO2 extraction to produce its Full and Broad-Spectrum CBD oil products. Using an advanced distillation process that leaves terpenes intact while removing all traces of THC, Colorado Botanicals produces high-quality Broad-Spectrum distillate.

This distillate does not contain waxes, chlorophyll, or unnecessary lipids. It has a mild taste that is made even more pleasant by its high terpene content.

Type of CBD

Most of Colorado Botanicals products are Broad Spectrum but they started offering Full Spectrum CBD oils. In contrast with Full-Spectrum CBD oil, this type of purified and refined CBD is entirely THC-free, assuaging potential concerns regarding THC contamination in CBD products.

What’s most impressive about Colorado Botanicals products is their high terpene concentrations. Often overlooked in the CBD industry, terpenes are beneficial substances found in Cannabis sativa that each has unique properties.

Focus on Terpenes

It’s important to note that the terpenes found in Colorado Botanicals Full and Broad-spectrum CBD oil are not reintroduced into the finished product. Instead, they are the original terpenes present in the CBD-rich hemp flower that Colorado Botanicals naturally retains.

Reintroduced terpenes can cause contamination issues, and they don’t provide the same effects as terpenes that are naturally present in CBD extract. We’re impressed that Colorado Botanicals knows the difference and their ability to naturally retain terpenes in its products.

About Terpenes

Why are terpenes so important? Scientists believe that terpenes may contribute to the entourage effect , which is a theorized form of Cannabis sativa synergy that may occur when cannabinoids and terpenes are used together.

Initially believed to primarily apply to interactions between cannabinoids, researchers have now recognized that terpenes may be just as essential to the activation of the entourage effect. CBD products that contain terpenes may be more effective or provide more benefits than products that do not.

Individual Effects of Terpenes

In addition to potentially contributing to the entourage effect, terpenes also have individual benefits. Found in many other plants aside from Cannabis sativa, terpenes have been studied for decades for their potential beneficial effects.

  • Beta-Caryophyllene – Beta-caryophyllene is one of the only terpenes that acts like a cannabinoid. It stimulates the nervous system’s CB2 receptors , which modulate inflammation. Unlike CB1 receptors, CB2 receptors do not cause intoxication. However, these neuroreceptors have dozens of potential beneficial effects aside from their observed impact on inflammation.
  • Humulene – Like most terpenes, humulene has been studied for its potential antioxidant and anti-inflammatory effects. Humulene is also one of a few terpenes that have been researched for their potential antimicrobial benefits .
  • Linalool – Along with humulene, linalool has been studied for its potential antimicrobial and antioxidant benefits . This terpene is found in lavender as well as hemp.
  • Bisabolol – A rare terpene, bisabolol has been studied for its potential ability to reduce skin inflammation , and the antimicrobial potential of this terpene has also been researched.

Terpene Lab Tests

To give you an idea of just how seriously Colorado Botanicals takes terpenes, here are the results from one of this brand’s recent lab tests:

Since testing for terpenes is an added service, most CBD brands fail to determine the exact concentrations of terpenes present in their products. Colorado Botanicals, on the other hand, makes sure that their third-party lab tests contain detailed terpene information.

Price per Milligram of CBD

The price per milligram of CBD varies among Colorado Botanicals products. We’ll use this brand’s 1500mg CBD tincture as a baseline, however, since many brands produce similar tinctures.

This product presently costs $110, so the CBD in this tincture costs $0.073 per milligram. This price is standard within the industry, and Colorado Botanicals tinctures offer added value due to their terpene content.

Lab Reports

Colorado Botanicals lab reports are available in PDF form in a public Google Drive folder that is linked on each product page. They test their products and extracts at FESA Labs and ProVerde Laboratories. They provide detailed information on the cannabinoid, terpene, and contaminant concentrations present in each product.

Customer Support

In our experience, Colorado Botanicals offered excellent customer support. This brand provides a contact form, email address, and phone number you can use to get in touch with customer service.

A representative answered the phone immediately when we called. We received a response to an emailed inquiry on the same day.

Certifications

Colorado Botanicals has received ISO 9001:2015 certification for its production facility. This brand uses cGMP processes to produce its products.

Pros & Cons

Here are the highs and lows of this exemplary CBD brand:

Pros

  • Broad-spectrum, THC-free CBD
  • Offers Full Spectrum CBD Oil now
  • Terpene-rich CBD extract
  • No reintroduced terpenes
  • Reasonable price-per-milligram
  • Detailed lab reports with lab reports page
  • ISO 9001:2015 certification
  • The best customer service we’ve come across in all the audits we did

Cons

  • Products aren’t significantly more affordable than options offered by competitors
  • Shipping is free over $74

Bluebird Botanicals: Best Full-Spectrum

Bluebird Botanicals has been around since 2012, and this brand is still going strong. While the quality of the full-spectrum and CBD isolate products Bluebird Botanicals offers certainly seems satisfactory, we were more impressed by this brand’s prices.

If you’re looking for quality CBD that’s lighter on the wallet, this is probably the best option. Normally, low price a red indicating poor quality. Bluebird Botanicals, however, proves that there are major exceptions to that rule.

Brand Credibility

Any CBD brand that’s been around for more than eight years carries plenty of clout. While the Bluebird Botanicals website was relatively cluttered, it contained plenty of helpful information, and this brand is highly transparent regarding where it sources its hemp and how it produces its products.

Extraction & Purification Standards

Bluebird Botanicals uses a mix of CO2 extraction and ethanol extraction. This brand then uses steam distillation to remove impurities from its extracts. It’s unclear why Bluebird also uses ethanol if this company also has access to CO2 extraction facilities.

Type of CBD

Most of the products Bluebird Botanicals offers include Full-Spectrum CBD. In contrast with Nuleaf, Bluebird uses distillation to remove impurities like chlorophyll from its CBD oil.

However, Bluebird leaves traces of THC behind in its extracts instead of choosing to produce Broad-spectrum CBD. To boost its lineup with THC-free products, Bluebird also provides a few offerings that contain CBD isolate.

Price per Milligram of CBD

Bluebird’s Extra Strength Classic CBD Oil tincture contains 1500mg CBD, and it costs $99.95. As a result, this product’s price-per-milligram is $0.066, making Bluebird Botanicals CBD highly affordable.

Lab Reports

Instead of linking to lab reports on product pages, Bluebird provides them all on a single page, making it difficult to access the report you’re looking for. This brand breaks its third-party lab results into multiple sections, making the process a bit more confusing.

However, Bluebird tests for terpenes, heavy metals, mycotoxins, and a variety of other variables. Even though the reports may be difficult to access, this brand’s lab reports are among the industry’s most thorough.

Customer Support

We found Bluebird’s customer service team to be highly accessible and responsive. This brand provides a contact form, a phone number, and multiple email addresses.

Certifications

Bluebird Botanicals has received a number of certifications, including:

  • B Corporation Certification
  • Leaping Bunny Cruelty-Free Certification
  • U.S. Hemp Authority Certification
  • Glyphosate Residue Free Certification

It does not appear, however, that Bluebird’s production facilities have been ISO certified.

Pros & Cons

Here’s what we liked and disliked about Bluebird Botanicals

Pros

  • An industry veteran with a great reputation
  • Highly certified brand
  • Detailed lab reports
  • Quality products

Cons

  • In THC-free products, CBD isolate is used instead of broad-spectrum CBD
  • Lab reports are hard to find
  • The website is somewhat cluttered

Nuleaf Naturals: Best By Reviews

Full-spectrum CBD can be hit-and-miss, but some CBD users swear by the benefits of Full-spectrum products. With more than 20,000 reviews, Nuleaf Naturals is the most popular provider of Full-spectrum hemp products on the market, and we like the simplicity of this brand’s product lineup.

We noticed positive effects and why it landed so high on the list despite the high cost it comes at.

Brand Credibility

Nuleaf Naturals is highly regarded, and this brand’s website is clean and simple. It’s hard not to feel like a brand has credibility when it has accumulated so many positive customer reviews.

Extraction & Purification Standards

Nuleaf uses CO2 to extract its CBD, further improving our impression of this brand. This brand uses a type of Full-Spectrum oil called winterized CBD, which is more raw than refined.

Type of CBD

Nuleaf Naturals products contain winterized Full-Spectrum CBD, which might appeal to some consumers since it’s so raw and unrefined. Winterized extract, however, contains waxes, chlorophyll, and other substances that might taste unpleasant or impair ingestion.

Price per Milligram of CBD

Nuleaf Naturals offers 1,800mg Full-Spectrum tinctures for $179. As a result, this brand’s CBD costs around $0.099 per milligram, one of the industry’s highest prices.

Lab Reports

Nuleaf’s lab reports are hard to find, and they aren’t product-specific. However, this brand’s third-party testing is provided by Botanacor, a reputable lab.

Customer Support

Nuleaf provides customer support via phone, email, and contact form. Our call was answered immediately since we called during business hours, but it took around 24 hours to receive a response to our email.

Certifications

Nuleaf Naturals doesn’t provide information regarding any certifications this brand might hold.

Pros & Cons

Here are what we considered to be the highs and lows of Nuleaf Naturals:

Pros

  • Offers some of the best full-spectrum CBD on the market
  • Over 20,000 satisfied customer reviews
  • Simple, clean website, & very easy to use
  • Been around for a long time and have built trust

Cons

  • High CBD price per milligram
  • They use Winterized CBD Extract so it isn’t purified like a distillate but winterized extracts do generally contain higher amounts of plant compounds which can be good and bad if not purified properly.
  • Lab results are vague and hard to find

Medterra: Highest Concentration

With more than 5,000 customer reviews, Medterra is one of the nation’s most popular CBD oil brands. The quality of Medterra’s CBD was exceptional, and we did like the cannabinoid content of their oil. They did contain higher amounts of cannabinoids than usually seen in CBD products. However, they didn’t test for terpenes, which doesn’t clarify if their extracts contain the terpene contents like Colorado Botanicals.

When testing out their CBD oil, we did notice it to be one of the most effective ones from this list, hence why we ranked it number 2 out of 10.

Brand Credibility

Medterra is certainly one of the most credible CBD oil brands. This company’s site content is on-point, and Medterra provides plenty of information on each of the products it produces.

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Extraction & Purification Standards

Medterra uses CO2 extraction to produce its products. Based on customer reviews and our own research, Medterra CBD is highly purified, and it doesn’t contain any waxes, excess lipids, or chlorophyll.

Type of CBD

Medterra used to offer Full-Spectrum CBD oil products. Nowadays, however, this brand only produces Broad-Spectrum CBD and CBD isolate products.

Price per Milligram of CBD

Medterra offers a 1000mg Broad-Spectrum CBD tincture for $59.99. As a result, this brand provides a CBD price-per-milligram of only $0.059, which is one of the lowest prices found in the industry.

Lab Reports

Third-party lab reports from Green Scientific Labs are easy to find on each Medterra product page. While these reports include results for dozens of solvents and pesticides, they do not include results for terpenes.

Unfortunately, it does not appear that Medterra takes the benefits of terpenes very seriously. This lamentable perspective is also clear to see in Medterra’s CBD isolate products, which don’t contain any terpenes whatsoever.

Customer Support

Medterra offers a live chat service. In our experience, however, customer service agents are rarely available for live chat. Instead, customers can contact Medterra by phone, email, or contact form.

Certifications

Medterra products are U.S. hemp authority-certified. However, this brand does not provide any information certifications it may have achieved for its production facilities.

Pros & Cons

Here are the key advantages and disadvantages of Medterra’s products:

Pros

  • Affordable products
  • Over 5,000 customer reviews
  • Easily accessible lab reports
  • Ultra Broad Spectrum CBD Oil has great cannabinoid profile
  • Offers Immune Boost CBD Oil that holds other ingredients

Cons

  • The benefits of terpenes are overlooked
  • Somewhat cluttered product catalog

cbdMD: Best Price

cbdMD is known for its prominent partnerships with athletes and other celebrities. The cbdMD website is remarkably well-built, and this brand produces informative content.

This brand’s products are pretty decent. But while it may not stack up to the above vendors, cbdMD still offers the best price we’ve seen so far. cbdMD also beats its competitors in terms of potency, with up to 7,500mg of CBD in a 30mL bottle.

Brand Credibility

cbdMD operates one of the best CBD eCommerce websites we’ve seen. This brand’s site loads quickly, and it’s full of informative content.

Extraction & Purification Standards

cbdMD uses CO2 extraction to produce its crude hemp extracts. While cbdMD doesn’t provide any information directly stating how it refines its extracts, we assume that this brand uses steam distillation.

Type of CBD

cbdMD products contain Broad-Spectrum CBD extract, though it’s hard to discover this fact without considerable research. This brand sources its hemp from farms located in the United States.

Price per Milligram of CBD

cbdMD offers a 1500mg tincture for $99.99. As a result, this product has a price-per-milligram of $0.067, which is relatively standard within the industry.

Lab Reports

We were very impressed with the procedure cbdMD uses to provide lab reports to consumers. First of all, this brand’s lab reports are conducted by SC Laboratories, one of the nation’s most respected independent labs.

There’s a huge, highlighted button on every product page that you can use to load cbdMD’s lab reports. These reports appear as a popup window, and there are buttons you can use to either download or print the lab report for a particular product.

cbdMD’s lab reports are remarkably detailed, but they reveal that this brand’s products don’t contain considerable concentrations of terpenes. We wish that cbdMD provided lab report archives, not just the results of the latest test.

Customer Support

cbdMD customer support is reachable by live chat, email, contact form, and phone. We found cbdMD’s email support agents to be responsive and helpful.

Certifications

In 2020, cbdMD received NSF International Good Manufacturing Practice (GMP) registration. This certification confirms that cbdMD’s production facilities adhere to the latest cGMP standards. cbdMD is also a member of the U.S. Hemp Roundtable.

Pros & Cons

Here’s a brief summary of the highs and lows of cbdMD:

Pros

  • Big, professional brand with a well-designed website
  • Reasonably priced products
  • Excellent, informative lab reports
  • Wide variety of products to choose from

Cons

  • We didn’t find the pet products to be effective as other pet products we’ve reviewed in the past

Honorable Mentions: Other Great CBD Brands

CBDistillery

We’ve been fans of CBDistillery ever since this brand only offered CBD isolate. Some things about CBDistillery have certainly improved over the years.

In terms of the quality and effectiveness of their oil, we found it effective but not quite enough to be at the top of this list, However, it is a great company to consider purchasing and trying.

Brand Credibility

In our opinion, CBDistillery is a credible company and is well-known in the CBD industry. One thing we noticed is that their lab reports were not easily accessible – they promote third-party testing as a priority.

At the same time, CBDistillery’s website is remarkably responsive and well-designed, and it’s populated with elegant, convincing content. CBDistillery is certainly one of the nation’s biggest CBD companies, which has forced this brand to be reasonably accountable.

Extraction & Purification Standards

CBDistillery uses CO2 extraction to produce its crude CBD extracts. Then, this brand uses steam distillation to produce high-purity isolates and distillates.

Type of CBD

CBDistillery offers a wide selection of Full-Spectrum, Broad-Spectrum, and Isolate CBD products. This brand’s catalog is well-rounded, but CBDistillery offers so many different products that it can be hard to zero in on an ideal formulation.

Price per Milligram of CBD

CBDistillery offers a 1000mg full-spectrum CBD tincture for $60. As a result, the price-per-milligram for this product is $0.06. Like most brands, CBDistillery progressively discounts its higher-dosage products.

Lab Reports

We were unable to find CBDistillery’s lab reports. While this brand claims its products are third-party lab tested, we couldn’t find them with a Google search.

Customer Support

CBDistillery offers a live chat, and this brand is also available by phone and contact form. We found CBDistillery’s customer support to be relatively engaging and responsive.

Certifications

We weren’t able to find any information on certifications that CBDistillery might possess.

Pros & Cons

Let’s summarize the high and low points of CBDistillery:

Pros

  • Veteran brand that has expanded significantly
  • Lots of product options
  • Competitive price-per-milligram
  • Great information easily accessible on their website for new CBD users who wouldn’t mind reading up on them

Cons

  • You have to complete a “Money-Back Guarantee Form” in order to get a refund
  • Third-party lab reports were missing

Charlotte’s Web

Charlotte’s Web rose to fame as one of the first CBD companies to directly target childhood epilepsy. Launched in 2011 as one of the earliest CBD brands, they became popular after helping a little girl named Charlotte Figi. She suffered from Dravet Syndrome, which is a rare form of epilepsy.

Her first seizure occurred when she was just three months old, which was said to have lasted a full 30 minutes. As she grew older, it worsened with multiple seizures per day, and doctors told the parents there was nothing they could do.

Or was there? When the family became introduced to cannabis and CBD, Charlotte’s Web owners, the Stanley brothers, who owned a cannabis dispensary, began supplying products to their family.

Charlotte Figi, who suffered from life-threatening seizures, saw considerable changes in her body as she continued to use the cannabis extract oil that the Stanley Brothers produced. Soon after seeing the positive impact it had on her life, the brothers decided to change the name to Charlotte’s Web in honor of her.

As CBD regulations have evolved, Charlotte’s Web has pivoted to offer a wide range of general-purpose CBD products.

In terms of their CBD oil and products’ quality, we didn’t find it as effective as the other brands listed here. They have a vast customer base and long-time customers, but we think that their customers will move over to other brands if they don’t improve their extracts’ quality.

Their CBD gummies did taste amazing, and we’re one of the more effective CBD gummies we’ve tried. If you’re looking for good-quality sleep gummies with melatonin, then we would highly recommend giving theirs a try.

Brand Credibility

At a glance, Charlotte’s Web website is well-built and content-rich. Charlotte’s Web bills itself as “the world’s most trusted hemp extract,” but it’s unclear whether this brand is also the world’s most trustworthy CBD producer.

Extraction & Purification Standards

Charlotte’s Web uses a combination of CO2 and isopropyl alcohol extraction techniques. It’s unclear why this brand doesn’t simply stick to CO2 extraction, which is cleaner and more reliable.

Type of CBD

Charlotte’s Web products include Full-Spectrum CBD extract. This brand doesn’t provide any information regarding whether its extracts are distilled or crude.

Price per Milligram of CBD

Charlotte’s Web uses creative measurements that make it relatively difficult to determine how much CBD is contained in each bottle of this brand’s tincture. However, after running some calculations, we’ve determined that Charlotte’s Web offers an 1800mg tincture for $119.99, which is priced fairly.

As a result, this product offers a price-per-milligram of $0.067. This price is standard.

Lab Reports

Charlotte’s Web makes it difficult to access lab reports for its products. You have to input the lot number for your product, which is only available on the product’s outer packaging. If you’re trying to look at their lab reports to help determine if you want to purchase over another brand, you won’t be able to.

Furthermore, Charlotte’s Web does its own in-house lab testing. Charlotte’s Web is the only major CBD brand we’re aware of that breaks from conventional testing in this way.

Customer Support

Charlotte’s Web customer service was reasonably responsive. You can contact this brand via live chat, contact form, or phone.

Certifications

Charlotte’s Web is a certified B Corporation.

Pros & Cons

Let’s summarize the best and worst aspects of Charlotte’s Web:

Pros

  • Reasonably priced products
  • Certified B Corp
  • Wide variety of products to choose from including Sleep Gummies, Recovery Gummies, & Calm Gummies.
  • Sleep gummies we’re very effective

Cons

  • No third-party lab reports, and lab reports are very difficult to access
  • Mixture of isopropyl alcohol and CO2 extraction methods
  • Long shipping times

Lazarus Naturals

There’s a lot we like about Lazarus Naturals. This brand exudes a down-to-earth, working-class mystique, and it features high-quality, organic products that appeal to sustainability-conscious consumers.

At the same time, Lazarus Naturals’ headlong focus on wholesale relationships has allowed this brand’s direct-to-consumer side of operations to suffer. The Lazarus Naturals website is relatively slow, and it’s hard to find pertinent information on this company’s products.

In terms of the quality of their CBD oil, we found it to be effective. They also have many long-time loyal customers, which explains a lot.

Brand Credibility

As a major CBD brand, Lazarus Naturals can’t help but be reasonably credible. Most of this brand’s products have a few dozen reviews, and the content featured on lazarusnaturals.com is convincing. We wish that Lazarus would make its product catalog more accessible to consumers.

Extraction & Purification Standards

Lazarus Naturals uses ethanol to produce its crude CBD extract, which is a low-cost option that many brands opt for. From there, this brand uses steam distillation to remove residual solvents, chlorophyll, and other undesirable substances.

Ethanol extraction is inferior to CO2 extraction.

Type of CBD

Lazarus Naturals offers a wide range of full-spectrum and CBD isolate products. The fact that this company does not offer any Broad-Spectrum CBD products casts doubt on the thoroughness of its extract purification process.

With modern distillation methods, it’s relatively easy to make broad-spectrum CBD. It’s possible that Lazarus is using an outdated form of distillation that might offer decreased product purity.

Price per Milligram of CBD

Lazarus Naturals offers a 15ml, 750mg CBD isolate tincture for only $24. This brand is kind enough to provide the price-per-milligram for this product directly on its product page: $0.032.

That’s one of the lowest, if not the lowest price-per-milligram we’ve ever seen. Rather than inspiring confidence, this rock-bottom price makes us wonder what Lazarus Naturals is sacrificing to keep costs so low.

Lab Reports

Third-party lab reports for Lazarus Naturals products are easy to find on every product page. This brand’s lab reports are provided by Columbia Laboratories, a little-known Portland, OR, analytics lab.

Customer Support

Lazarus Naturals is easy to reach by phone or email. We found this brand’s customer service agents to be responsive and helpful.

Certifications

Lazarus Naturals recently upgraded to a 40,000 square foot production facility in Portland. This brand’s new facility is cGMP-certified.

Lazarus Naturals products are also certified kosher. This is a step that other brands usually choose not to take even though almost all CBD products are inherently kosher.

Pros & Cons

Here’s a brief summary of the best and worst aspects of Lazarus Naturals:

Pros

  • Focus on sustainability and organic ingredients
  • Lab tests are third-party, recent, and easy to find
  • Price-per-milligram is very low

Cons

  • Website is relatively cluttered and difficult to navigate
  • Indirect evidence suggests that purification methods may be sub-par

Royal CBD

One of the first things you’ll see on Royal CBD’s website is “no room for mediocrity.” It’s a catchy and intense slogan that the vendor strictly follows.

An excellent source of Full-Spectrum and Broad-Spectrum CBD products, the company sources its extracts from organic, non-GMO hemp.

Brand Credibility

Royal CBD has a smaller online presence than bigger players like Lazarus Naturals or cbdMD. Still, the company boasts a respectable 2700 customer reviews listed on its website.

Royal CBD also deserves points for its well-written blog filled with plenty of relevant information for new CBD users. This resource undoubtedly makes it easier to choose the right product.

Extraction & Purification Standards

Royal CBD uses CO2 extraction to make its products, which leaves behind no trace solvents. But purity always starts at the source, which is why Royal gets its extracts from organically-grown, non-GMO Colorado hemp.

Type of CBD

Royal CBD exclusively offers full-spectrum CBD oils. However, they offer a Broad-Spectrum extract option in their line of gummies.

Price per Milligram of CBD

Royal CBD is one of the priciest brands we’ve seen (although there are some reasons why this is justified). Still, it’s a substantial investment.

For example, their highest concentration of 2500mg offers the best value per milligram. Although currently on sale for $229.00 as of the writing of this review, the original retail price is $289.00. This translates to about $0.12/mg.

That’s a huge price difference, considering our leading choice, Colorado Botanicals, sells a 3,000mg tincture for $199.99, or about $0.07/mg.

Lab Reports

Royal CBD repeatedly states that they perform third-party lab tests available to the public. However, after searching the site’s product pages, FAQ, and navigation tabs – along with a separate Google search – no links to these alleged results were listed.

Customer Support

Royal CBD offers customer support through phone or a generic contact form. Having a chat feature, however, would be helpful for quick, convenient answers.

Certifications

No information is available about any certifications or professional memberships Royal CBD may have.

Pros & Cons

Like all vendors, Royal CBD excels in some areas more than others.

Pros

  • Up to 83mg/ml
  • Organic
  • CO2 extracted
  • 15% subscription discount

Cons

  • Unable to find third-party lab reports
  • Terpenes are added after extraction
  • Very expensive compared to other CBD brands

JustCBD

“JustCBD” is a bit of a misnomer, given that the company offers the biggest variety of CBD products on our list. Aside from oils, creams, capsules, and edibles, JustCBD also sells products like vape juice and cartridges; bath bombs, honey sticks, and the new (albeit controversial) delta-8 THC.

It’s clear that, while the other companies on our list are health-focused, JustCBD caters to a broader audience with a range of therapeutic goals and strategies.

Brand Credibility

JustCBD doesn’t have a huge presence in the CBD community. However, it still has plenty of valuable blog posts with useful CBD-related guides and information. Unfortunately, we did catch them using Wikipedia as a source to describe the entourage effect in their FAQ section. On the other hand, we noticed some of their content is reviewed by a licensed medical doctor.

Extraction & Purification Standards

Extraction methods depend on the product. JustCBD’s Full-Spectrum oils use CO2 extraction. Their tinctures, on the other hand, are processed using alcohol to make them soluble with food and drinks.

Type of CBD

JustCBD offers two liquid options. Customers can choose between two CBD tinctures and a single Full-Spectrum CBD oil product.

Price per Milligram of CBD

JustCBD provides some of the best value on the market. Their 5,000mg 60oz bottle offers the highest concentration, at 83mg/ml.

With a retail price of only $144.99, this Full-Spectrum oil comes to about $0.01/mg. If you take advantage of their 30% discount on repeat orders, the price per milligram dips down to a fraction of a penny.

Lab Reports

JustCBD third-party tests its products. You can quickly find the results using your oil’s batch/lot number. There’s also the option to search by product category.

Customer Support

Clients can contact Customer Care through e-mail or phone. There isn’t a lot of information about the caliber of their service. But the handful of reviews on Trustpilot are mostly positive, with a couple of bad experiences.

Certifications

No information is available about any certifications or professional memberships.

Pros & Cons

JustCBD has a long way to go, with some strong selling points and a few opportunities for improvement.

Pros

  • 30% discount on repeat orders
  • Organic
  • CO2 extracted (full-spectrum oil)
  • Cheaper than any CBD product so far
  • Third-party tested

Cons

  • Offers delta-8 THC, which has been criticized by medical experts for its toxic extraction process
  • Has been the subject of two class-action lawsuits
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How Our Experts Chose the Best CBD Oil Brands of 2022

Toward the start of our guide, we provided some basic information on how we chose the criteria we used to grade each of the brands we examined. Then, with each brand review, we provided more detail on what made particular brands stand out and receive high grades.

We need to go into a little more detail, though, regarding how we came across and ended up choosing the winners in our list. Let’s examine the various methods that our experts used to find out which CBD oil brands offer the best products in the industry:

Customer Reviews

We’ve seen hemp companies brag that they offer the best CBD in existence. We’ve come across almost ludicrously arrogant marketing material and claims that couldn’t possibly be true.

That’s how we learned that sometimes, you need to take a look at reviews from actual customers to determine the quality of a CBD product. We’ll be honest, however, not even customer reviews are perfect.

Selective Reviewing

Unlike eCommerce giants like Amazon and Walmart, which are managed by third parties, CBD brands operate their own eCommerce websites. As a result, they’re able to remove reviews they don’t like.

  • The overall number of reviews a CBD product has received
  • Common themes listed in reviews
  • How reviews compare between brands

Expert Testimony

We’ve developed considerable in-house expertise when it comes to vetting CBD brands. At the same time, we know enough to know that we don’t know everything, which is why we used outside sources to back up some of our research.

To select the best CBD oils on the market today, we consulted with veteran consumers, popular CBD reviewers, and medical doctors. In some cases, we also took what brands had to say about themselves into account.

Original Research

We primarily determined which brands were worth our time by relying on our own research. Having determined a few essential criteria that separate good CBD products from bad, we did original research, and later parsed out our results into the more detailed criteria we’ve listed with each brand we reviewed.

Website Experience

You can learn a lot about a CBD brand within the first three seconds of navigating to its website. These days, there’s no excuse for a website to take longer than three seconds to load.

  • Clutter – If a CBD website was cluttered, visually confusing, or looked like it had been designed in 2004, we moved on immediately.
  • Content – A few spelling or grammatical errors here or there are to be expected. CBD entrepreneurs usually aren’t professional writers, after all. If the content on a website was offensively bad, however, or if it contained blatant claims (CBD cures ALL cancer. ), we knew we weren’t dealing with a reputable company.
  • Mobile-Responsiveness – Wow, this website looks great! Now, load it on your mobile device.

If elements overlap, it’s hard to find the menu, or images are too big, that site that looked so beautiful on a desktop isn’t properly mobile-responsive. Considering the fact that nearly 54% of eCommerce sales are expected to be completed on mobile devices in 2022, mobile optimization is no longer optional.

Brand Responsiveness

We already talked about each brand’s customer support in our reviews. Brand responsiveness, however, is slightly more complex than simply how quickly a brand responds to emails.

  • How developed is this brand’s social media presence?
  • How easy is it to contact that brand?
  • Does this brand offer its email or just a contact form?

These are examples of the questions we asked to determine each brand’s overall responsiveness.

Transparency

CBD companies have learned that they have to provide test results and other detailed product information if they want to succeed. How easy they make it to find this information, however, is up to each brand.

We preferred companies that went out of their way to provide as much information as possible on their products and processes. We avoided companies that made you work to learn what you needed to learn about their products’ quality and reliability.

Value

Value is more complex than simply how much each mg of CBD in your tincture costs. If a brand offers a cheap product, for instance, but makes customer service and returns impossible, for instance, it doesn’t actually provide high value.

This was perhaps the most important factor we considered as we assembled the 10 best CBD oils in this list. By evaluating dozens of different variables, we did our best to select the best overall value companies.

What You Should Know About CBD in 2022

Even though you’re now familiar with the 10 best CBD oil companies on the market, there’s still so much to learn about this non-intoxicating cannabinoid and what it has to offer. In this guide, we’ll provide more information on what CBD does and how to use CBD for a wide range of purposes.

What is CBD?

CBD is short for cannabidiol and is the most abundant active compound found in hemp, while THC is the most in marijuana.

CBD is just one of the 100+ cannabinoids found in hemp and marijuana. Other cannabinoids found in small amounts are Cannabigerol (CBG), Cannabinol (CBN), and Cannabichromene (CBC) to name a few that are similar to CBD but act on different receptors.

  • Isolated in 1940 but identified in 1963.
  • Safe and non-addictive substance.
  • It does not produce a “high” like Tetrahydrocannabinol (THC).
  • CBD can cause side effects such as dry mouth, diarrhea, reduced appetite, drowsiness, and fatigue.
  • CBD works by interacting with multiple receptors in our body that produces different effects.
  • CBD can interact with other medications when taken together since it gets broken down by the CYP450 enzyme that many prescription medications do.

How Does CBD Work?

According to a recent op-ed published in Cannabis Science and Technology, CBD may interact with your body in more than 20 distinct ways. However, scientists have recognized that the most important effects of CBD take place at two specific neuroreceptors.

For instance, researchers have closely researched the activity of CBD at the 5-HT1A receptor , which is the body’s most abundant serotonin receptor. Serotonin is responsible for dozens of critical bodily processes ranging from metabolism to mood regulation.

Scientists have also studied the effects of CBD at the TRPV1 receptor , which is involved in pain, inflammation, and epilepsy. CBD appears to exert the majority of its effects via these two biochemical interactions.

Does CBD Get You High?

CBD does not stimulate the CB1 receptor, which is the component of the endocannabinoid system that causes THC to make you feel high. Instead, CBD acts as an inverse agonist at this receptor, making it harder for your CB1 receptors to bind with THC.

As a result, CBD does not make you feel high. On the contrary, this cannabinoid usually produces a mild, non-intoxicating sense of relaxation.

Does CBD Have Side Effects?

The latest research on this subject , dating to 2019, indicates that CBD does not have any significant side effects. This cannabinoid is also remarkably non-toxic.

A few years ago, reports circulated that CBD causes liver damage. The study responsible for these reports was proven faulty, and its results have never been replicated.

Benefits of CBD

Scientists have researched the potential benefits of CBD for a wide range of diseases and conditions. Here are some examples:

Research into CBD for pain & inflammation

Both the 5-HT1A and TRPV1 receptors are involved in the sensation of pain. This year, researchers published a new study regarding the potential analgesic and anti-inflammatory properties of CBD, and efforts are ongoing to determine the exact analgesic potential of this non-intoxicating cannabinoid.

Research into CBD for depression & anxiety

Both depression and anxiety are largely modulated by the 5-HT1A receptor. In 2015, researchers took a deep dive into the potential antidepressant and anxiolytic properties of CBD, and research into this potential application of CBD is ongoing.

Research into CBD for sleep

Scientists are curious if the benefits of CBD may help you get to sleep at night. In 2019, for instance, a clinical study was conducted to determine the potential connection between CBD, anxiety, and sleep.

Research into CBD for cardiovascular health

Most types of cardiovascular disease are caused by either oxidative stress or inflammation. As a result, scientists have looked into the potential connections between CBD and cardiovascular health . While inconclusive at present, research into the potential cardiovascular benefits of CBD is ongoing.

Types of CBD Products

There are a few different ways to take CBD, and each ingestion method affects your body differently. Familiarize yourself with the four most common ways to use CBD:

Orally ingested CBD

CBD products that you chew up or swallow are considered orally ingested. Examples of orally ingested CBD products include capsules and gummies. While these CBD products are convenient and offer long-lasting effects, they have reasonably low bioavailability.

Sublingually ingested CBD

Because you hold CBD tinctures under your tongue before swallowing, these CBD products are considered sublingually ingested. Like orally ingested CBD, CBD tinctures end up in your digestive tract, but they have a chance to absorb through the thin membrane under your tongue before they enter your gut.

Topically applied CBD

Any CBD product you put on your skin is a topically applied CBD product. Types of topically applied CBD oil products include salves, lotions, and creams, and these products provide benefits in the area where they are applied.

Inhaled CBD

CBD flower and CBD vape cartridges are examples of inhaled CBD oil products. These products offer fast-acting, intense effects, but their benefits don’t last as long. Additionally, you should always exercise caution when allowing substances into your lungs.

How Much CBD Should I Take?

At present, there are no official guidelines regarding how much CBD you should take. Since this cannabinoid is non-toxic, non-intoxicating, and non-addictive, however, feel free to experiment as you determine which CBD dose is right for you.

As a general rule, you should start with a small CBD dose and increase the amount you consume as needed. Keep in mind that, since orally ingested CBD has low bioavailability, you might want to ingest more CBD per session if you use CBD capsules or edibles.

A good CBD dose to start with is 10mg to 20mg for the first 3 to 5 days to test your tolerance levels.

If you don’t feel noticeable effects from that dosage, increase your dose by 5mg to 10mg of CBD every 2 to 3 days to find your optimal dosage.

You may also start with higher doses, which is fine, but it’s essential to know that you may not notice the same effects after a couple of days or sometime after taking high doses. That’s just because you built a tolerance for CBD, and you should take a 3-5 day break from taking any CBD to reset your tolerance levels.

CBD FAQ for 2022 & Beyond

Let’s wrap up with some answers to common CBD questions:

1. Full Spectrum, Broad Spectrum, or CBD Isolate?

What is Full Spectrum CBD Oil?

Full Spectrum is a term used to describe a CBD hemp extract that contains a combination of cannabinoids, terpenes, flavonoids, and other plant oils that are extracted out of hemp. A key feature of Full Spectrum extracts, other than that it contains other compounds than just CBD, holds up to 0.3% THC per gram (1,000mg) of extract.

What is Broad Spectrum CBD Oil?

A Broad Spectrum extract is very similar to Full Spectrum, except they separate the THC using a chromatography system making it THC-Free. This type of product will show no detectable THC levels, and it’s so low that even at very high doses, it won’t cause any psychoactive effects.

What is CBD Isolate?

CBD Isolate is a white crystalline powder form of CBD that is usually 99.8% to 99.9% pure CBD. This type of CBD extract doesn’t contain any other cannabinoids, terpenes, or plant compounds. The purity might look appealing, but without other plant compounds, it can’t produce the Entourage Effect’s synergistic effect, so we recommend Full Spectrum or Broad Spectrum.

2. Which Type of CBD Extract is Best?

Without a doubt, buy Full Spectrum or Broad Spectrum CBD products. Why? These extracts contain other beneficial compounds like those mentioned above that synergically work together to interact with even more receptors than CBD can, producing an “entourage effect.”

3. What is the Entourage Effect?

Entourage Effect, or Whole Plant Extract, is the term used to describe multiple plant compounds working together synergistically. This synergistic effect increases multiple receptor channels’ activity to enhance the benefits of cannabis or CBD oil.

4. Why are terpenes in CBD important?

Terpenes are compounds found in many plants, including hemp. They are created to provide an aroma for plants and to protect plants from threats such as microorganisms, pathogens, predators, and herbivores, to name a few.

Terpenes go back to 1998 when Professors Raphael Mechoulam and Shimon Ben-Shabat found that the endocannabinoid system demonstrated an “ entourage effect ” when they noticed the activity of receptors had noticeably increased versus an isolated cannabinoid.

Besides that, terpenes have a wide range of benefits such as analgesic and/or anti-inflammatory, mood-enhancing, and modulating CBD effects by producing synergy with cannabinoids.

Here are four terpenes we touched upon above:

  • Beta-Caryophyllene – Beta-caryophyllene is one of the only terpenes that acts as a cannabinoid. It stimulates the nervous system’s CB2 receptors , which modulate inflammation. Unlike CB1 receptors, CB2 receptors do not cause intoxication. However, these neuroreceptors have dozens of potential beneficial effects aside from their observed impact on inflammation.
  • Humulene – Like most terpenes, humulene has been studied for its potential antioxidant and anti-inflammatory effects. Humulene is also one of a few terpenes that have been researched for their potential antimicrobial benefits .
  • Linalool – Along with humulene, linalool has been studied for its potential antimicrobial and antioxidant benefits . This terpene is found in lavender as well as hemp.
  • Bisabolol – A rare terpene, bisabolol, has been studied for its potential ability to reduce skin inflammation , and the antimicrobial potential of this terpene has also been researched.

There are noticeable differences in effects between CBD products with extracts containing terpenes versus CBD products without terpenes. Colorado Botanicals was the only company that showed a terpene profile test from a third-party lab while the other companies didn’t.

5. Why is CO2 extraction better for CBD?

Many hemp extraction processes leave residual solvents behind that can be passed along to the purified extract. CO2, however, is a harmless natural substance, so CO2 extraction doesn’t result in residual solvent contamination.

6. Does CBD Oil Show Up on a Drug Test?

Although the chances are low, yes, CBD oil can show up on a drug test if you use Full Spectrum CBD oil every single day or often. The reason why is because CBD oil can contain up to 0.3% THC.

If you’re worried about THC showing up on a drug test from taking CBD oil, you should purchase Broad Spectrum CBD oils as they are THC-Free. Colorado Botanicals, which earned our #1 spot for the best CBD company of 2022, manufactures Broad Spectrum CBD oil, which we believe is probably one of the best we’ve come across.

7. What part of the hemp plant does CBD come from?

CBD, or generally all cannabinoids, terpenes, and flavonoids, are found in the buds, flowers, and leaves of hemp plants but are usually most concentrated in the flowers.

8. Is hemp seed oil the same thing as CBD oil?

No, hemp oil is not the same as CBD oil and if you’re looking to purchase CBD oil and come across “hemp oil” online, on Amazon, or in a store, then make sure to read the label.

If you read the label and don’t see any acknowledgment of “Cannabidiol” or “CBD,” then it’s not CBD oil.

Although CBD oil is technically hemp oil, it’s mainly used to define hemp seed oil, which is entirely different from CBD oil even though they are from the same plant.

Hemp seed oil is from hemp seeds where they are cold-pressed for oil production, which is used in cooking, beauty products, or a nutritional supplement as it contains nutrients, fatty acids, and protein.

On the other hand, CBD oil is extracted from the flower and buds of hemp, usually using CO2 or Ethanol to pull out the beneficial compounds found in CBD products.

This oil includes CBD, minor traces of other cannabinoids such as CBG and CBN, along with terpenes and flavonoids.

9. Why is MCT oil sometimes used in CBD oil?

  • CBD hemp extract at room temperature crystallizes, which is a natural chemical process, so mixing it with a fatty oil, such as MCT oil, it keeps the hemp extract in liquid form.
  • You might come across other CBD tinctures with hemp seed oil or olive oil as the substitute oil, and it’s for this specific reason.
  • Evenly distributes the CBD hemp extract oil in a tincture by using MCT oil, allowing a consumer to simply fill the dropper to their desired CBD dosage.
  • MCT oil is tasteless.
  • MCT oil is a rich source of fatty acids that has health benefits.

10. Can CBD oil be USDA-certified organic?

Many brands cultivate organic hemp without seeking certification. However, according to leading hemp legal scholars , it is technically possible to achieve USDA-certified organic status for CBD products.

11. Can CBD Oil Expire?

Yes, CBD oil does expire and usually lasts for 12 to 18 months until it goes bad. Purchasing quality CBD products from reputable CBD brands, like the best CBD companies recommended above, is critical to avoiding products that degrade in quality sooner than they should.